Genomic News and Research

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New method can enhance the effectiveness of bacteria used in biotechnological applications

Scientists have developed a new computational technique that can be used to enhance the effectiveness of bacteria used in biotechnological applications.

13 Jul 2020

Researchers develop novel tool to maximize the power of deep learning for genomic studies

Researchers from the MDC have developed a new tool that makes it easier to maximize the power of deep learning for studying genomics.

13 Jul 2020

Newly identified gene variants in Black Americans could lead to precision prostate cancer therapies

Black men in the United States are known to suffer disproportionately from prostate cancer, but few studies have investigated whether genetic differences in prostate tumors could have anything to do with these health disparities.

11 Jul 2020

Establishment of global surveillance network can warn about next pandemic

The virus that causes COVID-19 probably originated in wild bats that live in caves around Wuhan, China, and may have been passed to a second animal species before infecting people, according to the World Health Organization.

10 Jul 2020

Upcoming phase II study to discover personalized therapy for patients at high risk for breast cancer relapse

Indiana University School of Medicine researchers Milan Radovich, PhD, and Bryan Schneider, MD, have discovered that the presence of circulating tumor DNA (ctDNA) and circulating tumor cells (CTCs) in the plasma of women's blood who have undergone chemotherapy prior to surgery for the treatment of stage 1, 2 or 3 triple negative breast cancer are critical indicators for the prediction of disease recurrence and disease-free survival.

10 Jul 2020

Scientists recommend a decentralized biosurveillance system to protect from diseases

The emergence of COVID-19 is a powerful reminder of how unchecked wildlife trade can lead to the spillover spread of viruses between wildlife and humans.

10 Jul 2020

UHN leads first-of-its-kind real world evidence study of medical cannabis

Medical cannabis is finally being put under the microscope, in a first-of-its-kind real world evidence study led by Dr. Hance Clarke, Director of Pain Services, Toronto General Hospital, and a recognized leader in educating Canadians about chronic pain management and the risk factors of continued opioid use.

9 Jul 2020

History of childhood abuse and intimate partner violence worsen women's posttraumatic symptoms

A study assessed the interaction of new and old relationship traumas among women three to 18 months after the birth of their child - one of the most challenging periods of their lives.

9 Jul 2020

DNA hypermethylation correlated with reduced amygdala volume in male patients with schizophrenia

Researchers at Kumamoto University, Japan have revealed that DNA methylation occurs in the gene that codes serotonin transporter (SERT), a protein that regulates neurotransmitter transmission, in schizophrenia and bipolar patients.

9 Jul 2020

ACTIONED consortium aims to transform future treatment of colorectal cancer patients

The Precision Medicine Centre of Excellence (PMC) at Queen's is leading a ground-breaking collaboration with the world's largest biotech company Roche, and Artificial Intelligence (AI) specialist, Sonrai Analytics.

9 Jul 2020

Researchers identify factor that regulates the abnormal growth of heart

The human heart is like a sponge, able to expand and grow, increasing its capacity to take up blood. In theory, an enlarged heart can also squeeze out more blood, with more power, than an average-sized heart. But in reality, for most people, this growth - known as cardiac hypertrophy - is abnormal and signals trouble.

9 Jul 2020

Genomics can perpetuate inequality and structural racism

Genomics is crowding out ways of reducing inequality, has thwarted medicine from advancing justice, and is creating new forms of social classification and surveillance.

9 Jul 2020

Research shows how SARS-CoV-2 alters translation

Now, a new study published on the preprint server bioRxiv in July 2020 shows that the 5’ end of the RNA molecule is capable of inhibiting the binding of mRNA to the ribosomal 40S subunit, thus preventing translation.

9 Jul 2020

Researchers map RNA structure throughout SARS-CoV-2 genome

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is currently at the heart of a pandemic that has cost the world more than 550,000 lives, 12 million infections, and uncounted years of productivity, is an RNA virus with the largest genome among all such viruses. This 30 kb size virus has caused many difficulties for scientists in search of a vaccine.

9 Jul 2020

New method helps pinpoint new potential therapeutic targets for lupus

A team of researchers from Children's Hospital of Philadelphia (CHOP) used a new method of pinpointing potential disease-causing changes in the genome to identify two new potential therapeutic targets for lupus, while also paving the way for more accurately identifying disease-causing variations in other autoimmune disorders.

8 Jul 2020

Tracing adaptation to ACE2 use in sarbecoviruses

A detailed study published on the preprint server bioRxiv in July 2020 argues that recombination accounts for the appearance of the ability of both SARS-CoV and SARS-CoV-2 to use the human angiotensin-converting enzyme (hACE) 2 as the binding receptor mediating viral infection of human cells.

8 Jul 2020

Research sheds doubt on the Pangolin link to SARS-CoV-2

A startling new study by researchers at the Broad Institute of MIT and the University of British Columbia and published on the preprint server bioRxiv* in July 2020 casts doubt on the hypothesis that the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was transmitted from pangolins acting as the intermediate host. Instead, the authors suggest, the pangolins themselves were incidentally infected from other animals in captivity or from humans.

8 Jul 2020

Zebrafish study finds few health impacts of 5G wireless technology

Findings from an Oregon State University study into the effects of radiofrequency radiation generated by the wireless technology that will soon be the standard for cell phones suggest few health impacts.

8 Jul 2020

Fred Hutch joins new clinical trials network to fight COVID-19

Fred Hutchinson Cancer Research Center has been named the coordinating center for vaccine clinical trials of the COVID-19 Prevention Network.

8 Jul 2020

Risk of severe COVID-19 in ~50 kb genomic segment inherited from Neanderthals

Researchers have found that a small fragment of the genetic code that has been inherited by modern humans from Neanderthals could carry the secret of why some people succumb to a severe form of COVID-19 requiring hospitalization, while others recover.

7 Jul 2020

Genomic News and Research

New method can enhance the effectiveness of bacteria used in biotechnological applications

Researchers develop novel tool to maximize the power of deep learning for genomic studies

Newly identified gene variants in Black Americans could lead to precision prostate cancer therapies

Establishment of global surveillance network can warn about next pandemic

Upcoming phase II study to discover personalized therapy for patients at high risk for breast cancer relapse

Scientists recommend a decentralized biosurveillance system to protect from diseases

UHN leads first-of-its-kind real world evidence study of medical cannabis

History of childhood abuse and intimate partner violence worsen women's posttraumatic symptoms

DNA hypermethylation correlated with reduced amygdala volume in male patients with schizophrenia

ACTIONED consortium aims to transform future treatment of colorectal cancer patients

Researchers identify factor that regulates the abnormal growth of heart

Genomics can perpetuate inequality and structural racism

Research shows how SARS-CoV-2 alters translation

Researchers map RNA structure throughout SARS-CoV-2 genome

New method helps pinpoint new potential therapeutic targets for lupus

Tracing adaptation to ACE2 use in sarbecoviruses

Research sheds doubt on the Pangolin link to SARS-CoV-2

Zebrafish study finds few health impacts of 5G wireless technology

Fred Hutch joins new clinical trials network to fight COVID-19

Risk of severe COVID-19 in ~50 kb genomic segment inherited from Neanderthals

The art of CRISPR: The power and promise of gene editing eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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