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Developing and refining muscle atrophy models for drug discovery

With the intensification of global population aging, muscle atrophy, characterized by the loss of muscle mass and function, has become an important health issue affecting the elderly. Researchers have widely used various animal and cellular models to gain a deeper understanding of the pathophysiological mechanisms of muscle atrophy and develop effective treatment strategies.

9 Jan 2025

A large-scale tongue cancer organoid library for precision oncology

Oral cancer is an increasingly prevalent disease worldwide, with over 300,000 new cases diagnosed each year. Among oral cancers, tongue cancer (TC) is the most common type and often carries a poor prognosis. Surgery combined with chemoradiotherapy is one of the main lines of treatment for high-risk cases of TC.

9 Jan 2025

$20 million grant to explore the role of viruses in human health

For over a decade, scientists have studied the microbiome, the environment of microorganisms that live on and in the body, and how it affects health and disease.

9 Jan 2025

AI-enhanced algorithm improves diagnosis of REM sleep behavior disorder

A Mount Sinai-led team of researchers has enhanced an artificial intelligence (AI)-powered algorithm to analyze video recordings of clinical sleep tests, ultimately improving accurate diagnosis of a common sleep disorder affecting more than 80 million people worldwide.

9 Jan 2025

Simple green synthesis of silver nanoparticles from goji berries

As the search for sustainability permeates all fields, researchers are turning to a unique organic source for creating antibacterial silver nanoparticles (Ag-NPs) – the humble goji berry.

9 Jan 2025

Ingenza partners with HydRegen to advance sustainable biomanufacturing

Ingenza's collaboration with HydRegen focuses on optimizing enzyme expression, paving the way for greener, cost-effective manufacturing of amine chemicals.

From Ingenza Ltd 9 Jan 2025

Geneoscopy closes $105 M in Series C funding round to power next-generation of gastrointestinal diagnostic tests

Geneoscopy, Inc., a life sciences company focused on developing diagnostic tests for the advancement of gastrointestinal health, today announced the closing of a Series C funding round raising $105 million.

9 Jan 2025

Functional characterization of variants improves cancer risk assessment and treatment

Findings from a multi-institutional, international study led by researchers from the Mayo Clinic Comprehensive Cancer Center have significantly advanced the understanding of genetic alterations in the BRCA2 gene, a key player in hereditary cancer risk.

9 Jan 2025

Researchers uncover molecular mechanisms driving RNA processing defects in Huntington's disease

A University of California, Irvine-led research team has discovered intricate molecular mechanisms driving the RNA processing defects that lead to Huntington's disease and link HD with other neurodegenerative disorders such as amyotrophic lateral sclerosis, frontotemporal lobar dementia and Alzheimer's disease.

8 Jan 2025

Robot use associated with increased employee retention, improved quality of care in nursing homes

Facing high employee turnover and an aging population, nursing homes have increasingly turned to robots to complete a variety of care tasks, but few researchers have explored how these technologies impact workers and the quality of care.

8 Jan 2025

New AI system aims to improve real-world application of clinical trial results

A new study led by Winship Cancer Institute of Emory University and Abramson Cancer Center of University of Pennsylvania researchers demonstrates that a first-of-its-kind platform using artificial intelligence (AI) could help clinicians and patients assess whether and how much an individual patient may benefit from a particular therapy being tested in a clinical trial.

8 Jan 2025

3D printed bone scaffolds successfully used to rebuild jawbone

Clinicians have successfully used custom-made 3D printed bone scaffolds, printed on-site at The University of Queensland, to rebuild part of a man's jawbone.

8 Jan 2025

Elderberry juice improves metabolic health and weight management

Elderberry juice may be a potent tool for weight management and enhancing metabolic health, according to a recent Washington State University-led study.

8 Jan 2025

AI analysis reveals optimal follicle sizes for IVF success

During IVF treatment, doctors use ultrasound scans to monitor the size of follicles - small sacs in the ovaries containing eggs - to decide when to give a hormone injection known as the 'trigger' to prepare the eggs for collection and ensure that they are ready to be fertilised with sperm to create embryos.

8 Jan 2025

UiA leads project to integrate robots into healthcare services

Out of a total of 113 applications to the Research Council of Norway, the project "Service robots as work support in municipal health and care services" (SAKO) was one of only ten projects to receive funding in December.

8 Jan 2025

AI technology supports global efforts against antimicrobial resistance

AMR is when microorganisms that cause infections, such as bacteria and viruses, change over time and no longer respond to antibiotic medicines.

8 Jan 2025

Study links glymphatic system damage to vascular dementia

A new study from the Keck School of Medicine of USC has tested a biomarker linked to vascular dementia across four separate groups and proposed an explanation for how cognitive impairment arises.

8 Jan 2025

AI-designed drug shows promise for inflammatory bowel disease

Insilico Medicine ('Insilico'), a clinical-stage generative artificial intelligence (AI)-driven drug discovery and development company, today announces positive results from two Phase I studies in Australia and China of ISM5411, a novel gut-restricted and PHD specific Inhibitor designed and optimized with the support of Insilico's Chemistry42 commercially-available generative reinforcement learning platform, for Inflammatory Bowel Disease (IBD).

8 Jan 2025

AI-based tool identifies subtypes of Type 2 diabetes using glucose monitors

Diabetes has long been lumped into two categories - Type 1, which often appears in childhood, or Type 2, which is associated with obesity and typically develops later in life. But scientists have learned that not all patients with Type 2 diabetes are the same, with some patients varying in body weight, age of onset and other characteristics.

7 Jan 2025