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Location matters for inflammation clearance

Health conditions that involve inflammation run the gamut, from multiple sclerosis and lupus to arthritis, diabetes, and cancer. While inflammation can serve as a normal response to help the body deal with injury or infection, problems arise when it persists, potentially harming surrounding tissues.

20 Nov 2018

Receptor structure could be key to developing new osteoporosis drugs

Researchers at the University of Zurich have determined the three-dimensional structure of a receptor that controls the release of calcium from bones. The receptor is now one of the main candidates for developing new drugs to treat osteoporosis.

19 Nov 2018

Artificial bone-like substance mimics the way real bone grows at atomic level

Researchers from Chalmers University of Technology, Sweden, have discovered how our bones grow at an atomic level, showing how an unstructured mass orders itself into a perfectly arranged bone structure.

19 Nov 2018

Women can be as resilient as men in undertaking arduous physical activity

Women that underwent extreme physical training and completed a transantarctic expedition did not show any more negative health effects than would be expected in men, according to a study presented at the Society for Endocrinology annual conference in Glasgow.

19 Nov 2018

Scientists equip new virus that kills carcinoma cells with protein

Scientists have equipped a virus that kills carcinoma cells with a protein so it can also target and kill adjacent cells that are tricked into shielding the cancer from the immune system.

19 Nov 2018

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

A majority of the HIV-infected cells that persist in HIV-infected individuals even during suppressive antiretroviral therapy originated from cellular proliferation, not viral replication, according to new research published in Nature Communications.

17 Nov 2018

Infant gut microbes altered by mother's obesity may increase risk for future disease

Infant gut microbes altered by their mother's obesity can cause inflammation and other major changes within the baby, increasing the risk of obesity and non-alcoholic fatty liver disease later in life, according to researchers at the University of Colorado Anschutz Medical Campus.

16 Nov 2018

Treating children with 'bubble baby disease'

An international study published in the journal Blood by researchers led by Dr. Elie Haddad, a pediatric immunologist and researcher at CHU Sainte-Justine and professor at Université de Montréal, highlights the urgent need to develop better treatment strategies for patients suffering from severe combined immune deficiency.

15 Nov 2018

Endocrine Society chooses four Diabetes Caucus leaders as winners of Diabetes Champion Award

The Endocrine Society today announced it has chosen Senator Susan Collins, Representative Tom Reed, Senator Jeanne Shaheen, and Representative Diana DeGette of the Congressional Diabetes Caucus as winners of its prestigious Diabetes Champion Award.

15 Nov 2018

New diabetes drugs linked to increased risk of lower-limb amputation and ketoacidosis

The use of a new class of drugs in the treatment of type 2 diabetes, so called SGLT2 inhibitors, are linked to a twofold increased risk for lower-limb amputation as well as diabetic ketoacidosis, a serious diabetes complication.

14 Nov 2018

Scientists harness power of natural killer cells to treat children with neuroblastoma

Researchers have made rapid advances in understanding how to manipulate the immune system safely to destroy cancer cells. Adoptive transfer of haploidentical natural killer (NK) cells has shown promise as a treatment option to target and kill cancer cells in a less toxic way than conventional therapies.

14 Nov 2018

Study sheds light on mechanisms that prevent autoimmune attack

Understanding the mechanisms that prevent our immune system damaging healthy cells, whilst fighting infection and cancer, could lead to the development of novel immune-regulating treatments.

14 Nov 2018

Lifting weights for less than an hour a week may reduce cardiovascular disease risk

Lifting weights for less than an hour a week may reduce your risk for a heart attack or stroke by 40 to 70 percent, according to a new Iowa State University study. Spending more than an hour in the weight room did not yield any additional benefit, the researchers found.

13 Nov 2018

Survey: Majority of Americans are concerned about health threat posed by antibiotic resistance

Nearly two thirds of Americans (65%) say antibiotic resistance is a public health problem and a strong majority (81%) say they are concerned that antibiotic resistance will make more infections difficult or impossible to treat and even deadly, according to a national public opinion survey commissioned by Research!America in collaboration with the Infectious Disease Society of America.

13 Nov 2018

Cancer stem cells depend on amino acid metabolism, and it's proving to be their Achilles' heel

Think of energy metabolism like a party popper: Ripping something apart releases a bang. Most of your cells rip apart sugar to release the "bang" of energy. Sometimes they rip apart fats, and in a pinch, cells can even metabolize protein.

13 Nov 2018

Study shows novel strategy to reduce breast cancer bone metastasis

Uncovering a novel mechanism that promotes growth of breast cancer bone metastasis has revealed a potential Achilles' heel for these cancer cells. Reported in the journal Cancer Cell, the study shows that interfering with this mechanism can reduce the risk of relapses in animal models.

12 Nov 2018

Fish oil and vitamin D pills no guard against cancer or serious heart trouble

A widely anticipated study has concluded that neither vitamin D nor fish oil supplements prevent cancer or serious heart-related problems in healthy older people, according to research presented Saturday at the American Heart Association Scientific Sessions. Researchers defined serious heart problems as the combined rate of heart attacks, stroke and heart-related deaths.

12 Nov 2018

Study shows benefits of new spinal fusion surgical home pathway

A standardized care pathway for children with adolescent idiopathic scoliosis undergoing spinal fusion surgery reduces the need for opioid pain medications and shortens hospital stays at Children's National Health System.

9 Nov 2018

New oral drug reduces menstrual bleeding for women with common uterine tumors

A new oral drug significantly reduced menstrual bleeding for women with the most common gynecologic tumors in the United States - benign tumors that disproportionately affect African-Americans, an international clinical trial found.

9 Nov 2018

Cells retain memory of chemical signals to which they are exposed

We all start out as a clump of identical cells. As these cells divide and multiply, they gradually take on distinct identities, acquiring the traits necessary to form, for instance, muscle tissue, bone, or nerves. A recent study from Rockefeller scientists offers new insight into how these cellular identities are cultivated over the course of development.

9 Nov 2018

Bone News and Research

Location matters for inflammation clearance

Receptor structure could be key to developing new osteoporosis drugs

Artificial bone-like substance mimics the way real bone grows at atomic level

Women can be as resilient as men in undertaking arduous physical activity

Scientists equip new virus that kills carcinoma cells with protein

Reducing cellular proliferation could help deplete HIV reservoir and lead to a functional cure

Infant gut microbes altered by mother's obesity may increase risk for future disease

Treating children with 'bubble baby disease'

Endocrine Society chooses four Diabetes Caucus leaders as winners of Diabetes Champion Award

New diabetes drugs linked to increased risk of lower-limb amputation and ketoacidosis

Scientists harness power of natural killer cells to treat children with neuroblastoma

Study sheds light on mechanisms that prevent autoimmune attack

Lifting weights for less than an hour a week may reduce cardiovascular disease risk

Survey: Majority of Americans are concerned about health threat posed by antibiotic resistance

Cancer stem cells depend on amino acid metabolism, and it's proving to be their Achilles' heel

Study shows novel strategy to reduce breast cancer bone metastasis

Fish oil and vitamin D pills no guard against cancer or serious heart trouble

Study shows benefits of new spinal fusion surgical home pathway

New oral drug reduces menstrual bleeding for women with common uterine tumors

Cells retain memory of chemical signals to which they are exposed

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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