Fibrosis News and Research

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Fibrosis is the growth of fibrous tissue.

Acologix demonstrates improved bone architecture in rat model of chronic kidney disease

Acologix, Inc. will present data indicating that its therapeutic product candidate AC-200 improved bone architecture in a rat model of chronic kidney disease.

8 Nov 2008

Australian-led global initiative to improve diagnosis of genetic disorders

An Australian-led global initiative to improve the diagnosis of genetic disorders and reduce errors in the reporting of genetic variations has been published today in the prestigious scientific journal Science.

7 Nov 2008

Healing process found to backfire in idiopathic pulmonary fibrosis patients

A mechanism in the body which typically helps a person heal from an injury, may actually be causing patients with idiopathic pulmonary fibrosis (IPF) to get worse, researchers at the National Institute of Environmental Health Sciences (NIEHS), a part of the National Institutes of Health (NIH), and their collaborators have found.

27 Oct 2008

Universal test for genetic diseases in unborn children in the pipeline

A team of British scientists have developed a ground-breaking new test to screen for genetic diseases in unborn children.

27 Oct 2008

Simple gene-based blood test, quicker, more accurate evaluation for cystic fibrosis

Researchers at National Jewish Health have identified a simple gene-based blood test that more accurately and quickly measures cystic fibrosis patients' response to therapy than current tests.

26 Oct 2008

Resveratrol shows promise for treating human alcoholic fatty liver disease

The accumulation of fat in the liver as a result of chronic alcohol consumption could be prevented by consuming resveratrol, according to a new study with mice. The research found that resveratrol reduced the amount of fat produced in the liver of mice fed alcohol and, at the same time, increased the rate at which fat within the liver is broken down.

14 Oct 2008

Kamada reports positive data with inhaled Alpha-1 Antitrypsin in cystic fibrosis

Kamada has announced today positive data from its Phase II study evaluating inhaled Alpha-1 Antitrypsin (AAT) delivered via an Investigational eFlow Nebulizer System (PARI Pharma GmbH), in the treatment of cystic fibrosis. The results demonstrate the product has an excellent safety profile and shows promising signs of efficacy, as indicated by a reduction in lung inflammation.

12 Oct 2008

Children with cystic fibrosis not well covered by guidelines for vitamin D needs

Existing recommendations for treating vitamin D deficiency in children with cystic fibrosis (CF) are too low to cover the serious need, leaving most at high risk for bone loss and rickets, according to researchers at Johns Hopkins Children's Center.

12 Oct 2008

New pig model of cystic fibrosis provides better understanding of human disease

For the first time, researchers have developed a genetically altered animal model for cystic fibrosis (CF) that closely matches the characteristics of the disease in humans. By studying the complex and multi-organ disease process in the pig model, researchers can now better understand how the complications of CF develop, an advancement that may lead to new avenues for research in prevention and treatment.

25 Sep 2008

Some cases of breast cancer overtreated

According to a new study standard radiation therapy for some breast cancer patients may not be medically required and may, therefore, be causing unnecessary serious side effects.

24 Sep 2008

Protein opens hope of treatment for cystic fibrosis patients

Scientists have finally identified a direct role for the missing protein that leaves cystic fibrosis patients open to attack from lung-damaging bacteria, the main reason most of them die before their 35th birthday, scientists heard today (Thursday 11 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at Trinity College, Dublin.

10 Sep 2008

New drug hope for cystic fibrosis patients

A science conference in the UK has heard some good news which offers hope to cystic fibrosis (CF) patients worldwide.

10 Sep 2008

New drug hope for cystic fibrosis patients

A new drug therapy may represent a tremendous step forward in the treatment of some 70,000 cystic fibrosis (CF) patients worldwide, Dr David Sheppard from the University of Bristol told an audience at the BA Festival of Science in Liverpool today [9 September].

9 Sep 2008

Rattlesnake-type poisons used by superbug bacteria to beat our defences

Colonies of hospital superbugs can make poisons similar to those found in rattlesnake venom to attack our bodies' natural defences, scientists heard today (Monday 8 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at Trinity College, Dublin.

7 Sep 2008

Second phase 3 trial of Bronchitol in cystic fibrosis sufferers begins

Pharmaceutical company Pharmaxis today announced that it has enrolled the first subject into its second pivotal Phase 3 clinical trial evaluating Bronchitol in cystic fibrosis sufferers.

4 Sep 2008

Clinical trial advances cystic fibrosis therapy

Axentis Pharma AG has initiated a clinical phase IIa trial to assess the safety and tolerability of a new therapeutic formulation for the treatment of severe pulmonary infection in cystic fibrosis patients. The new formulation allows an established therapeutic agent to be delivered directly to the site of infection. The forthcoming trial will also compare the effects of two different doses of the new drug.

4 Sep 2008

Non-invasively measuring liver stiffness with transient elastography accurately identifies advanced liver disease without biopsy

Non-invasively measuring liver stiffness with transient elastography accurately diagnoses patients with late-stage liver disease, reports a new study in Clinical Gastroenterology and Hepatology, the official journal of the American Gastroenterological Association (AGA) Institute.

1 Sep 2008

Scientists engineer first drug-delivery particles capable of passing through human mucus

Chemical engineers from Johns Hopkins University have broken the "mucus barrier," engineering the first drug-delivery particles capable of passing through human mucus - regarded by many as nearly impenetrable - and carrying medication that could treat a range of diseases. Those conditions include lung cancer, cervical cancer and cystic fibrosis, the research noted in a presentation scheduled for the 236th National Meeting of the American Chemical Society.

20 Aug 2008

Breakthrough drug FT-11 has the potential to end the need for dialysis in kidney disease

Australian scientists say they have developed a drug with the potential to save millions of lives from kidney disease.

18 Aug 2008

New drug targets main culprit in common colds

The Melbourne drug company Biota has announced trials of a drug to treat the human rhinovirus (HRV) which is the main culprit in the common cold.

12 Aug 2008

Fibrosis News and Research

Further Reading

Acologix demonstrates improved bone architecture in rat model of chronic kidney disease

Australian-led global initiative to improve diagnosis of genetic disorders

Healing process found to backfire in idiopathic pulmonary fibrosis patients

Universal test for genetic diseases in unborn children in the pipeline

Simple gene-based blood test, quicker, more accurate evaluation for cystic fibrosis

Resveratrol shows promise for treating human alcoholic fatty liver disease

Kamada reports positive data with inhaled Alpha-1 Antitrypsin in cystic fibrosis

Children with cystic fibrosis not well covered by guidelines for vitamin D needs

New pig model of cystic fibrosis provides better understanding of human disease

Some cases of breast cancer overtreated

Protein opens hope of treatment for cystic fibrosis patients

New drug hope for cystic fibrosis patients

New drug hope for cystic fibrosis patients

Rattlesnake-type poisons used by superbug bacteria to beat our defences

Second phase 3 trial of Bronchitol in cystic fibrosis sufferers begins

Clinical trial advances cystic fibrosis therapy

Non-invasively measuring liver stiffness with transient elastography accurately identifies advanced liver disease without biopsy

Scientists engineer first drug-delivery particles capable of passing through human mucus

Breakthrough drug FT-11 has the potential to end the need for dialysis in kidney disease

New drug targets main culprit in common colds

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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