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New “GPS nanoparticle” delivers a genetic punch to the protein implicated in tumor spread

A newly developed "GPS nanoparticle" injected intravenously can home in on cancer cells to deliver a genetic punch to the protein implicated in tumor growth and spread, according to researchers from Penn State.

11 Mar 2024

LAG-3 protein structure may be the key to unlocking new cancer treatments

A molecular “snapshot” of a protein can be critical to understanding its function. Scientists at Stanford and NYU have published and investigated a new structure of the protein LAG-3 which could enable the development of new cancer treatments.

11 Mar 2024

Study highlights potential therapeutic target for immune-related disorders

A new study highlights a potential therapeutic target for immune-related disorders, such as multiple sclerosis and asthma.

11 Mar 2024

Scientists find answers about cardiovascular diseases by probing the cellular "glue"

University of Virginia School of Medicine scientists have found important answers about strokes, heart attacks and cardiovascular diseases by probing the biological glue our bodies create to protect us from those deadly dangers.

11 Mar 2024

UCLA and UAMS teams secure $3.2 million NIH grant for melanoma research

A team of investigators from the UCLA Health Jonsson Comprehensive Cancer and the University of Arkansas for Medical Sciences (UAMS) Winthrop P. Rockefeller Cancer Institute was awarded a $3.2 million grant from the National Institutes of Health to identify new ways to prevent and overcome treatment resistance to targeted therapy in patients with all sub-types of cutaneous melanoma, an aggressive form of skin cancer.

11 Mar 2024

Wristwatch-like devices detect early signs of Alzheimer's

Monitoring daily activity patterns using a wrist-worn device may detect early warning signs of Alzheimer's disease, according to a new study led by researchers at the Johns Hopkins Bloomberg School of Public Health.

11 Mar 2024

Ubiquigent enters agreement with Astellas subsidiary, Nanna Therapeutics

Agreement leverages Ubiquigent’s DUB-focused drug discovery platform to support the development of novel therapeutic candidates for multiple disease targets selected by Nanna Therapeutics.

From Ubiquigent Limited 11 Mar 2024

Researchers identify cold-sensing protein in mammals

University of Michigan researchers have identified the protein that enables mammals to sense cold, filling a long-standing knowledge gap in the field of sensory biology.

11 Mar 2024

Study finds plant proteins improve rest, animal proteins may disrupt

Plant protein intake is associated with improved sleep quality, while animal protein, particularly from processed red meat and poultry, is linked to worse sleep, with no significant effect from total protein intake on sleep quality.

10 Mar 2024

Nutrition's crucial role in Alzheimer's progression revealed

Study highlights the strong association between nutrition, particularly malnutrition, and the risk and progression of Alzheimer's disease, emphasizing early dietary interventions as key to reducing AD's global burden.

10 Mar 2024

mRNA vaccines train T cells in waves, study shows

mRNA vaccines developed against the spike glycoprotein of severe acute respiratory syndrome type 2 coronavirus (SARS-CoV-2), displayed remarkable efficiency in combating coronavirus 19 (COVID-19).

9 Mar 2024

Key protein identified in protecting women from fatty liver disease

New research from Karolinska Institutet in Sweden shows how oestrogen protects against MASLD, a fatty liver disease that has increased dramatically during the current obesity epidemic.

9 Mar 2024

Researchers develop precise drugs to target HIV's Nef protein

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

9 Mar 2024

Study reveals key mechanism of PD-1 function

Insights into the workings of an immune cell surface receptor, called PD-1, reveal how treatments that restrict its action can potentially be strengthened to improve their anticancer effect, a new study shows.

9 Mar 2024

Sleep boosts immune cell mobility toward lymph nodes

Researchers at LMU Munich have shown that sleep enhances the migratory potential of T cells toward lymph nodes.

8 Mar 2024

U-M research offers a new path forward in the development of anti-HIV drugs

A team of University of Michigan researchers has successfully modified a naturally occurring chemical compound in the lab, resulting in advanced lead compounds with anti-HIV activity.

8 Mar 2024

Link between nutrient intake and multimorbidity risk reported in recent study, more research is needed

In a recent study published in BMC Public Health, researchers explored potential associations between nutrient intake and multimorbidities.

8 Mar 2024

Tryptophan digestion by gut microbiome spurs arthritis inflammation

A University of Colorado Department of Medicine faculty member says she and her colleagues have identified the means in which bacteria in the digestive system can break down tryptophan in the diet into an inflammatory chemical that primes the immune system towards arthritis.

7 Mar 2024

Man takes 217 COVID vaccines with no ill effects, shows immune boost

A case report of a 62-year-old man receiving 217 SARS-CoV-2 vaccinations over 29 months reveals no adverse effects, increased T-cells, and spike-specific antibodies, providing unique insights into the effects of hyper-vaccination on immune responses.

7 Mar 2024