Transplant News and Research

RSS

Study demonstrates significant mortality rate among non-adhering heart transplant adolescent patients

After receiving an organ transplant, patients must follow a regimented medication routine to maintain the health of their graft (transplanted organ). Failure to do so, known as non-adherence (NA), can result in life-threatening illness.

4 Jun 2013

Diaxonhit, XDx agree to market and perform AlloMap Molecular Expression Testing in Europe

Diaxonhit, the leading French provider of specialty diagnostic solutions, and XDx, Inc., a U.S. molecular diagnostics company focused on non-invasive tests for transplantation and autoimmune disease, announced today that they have entered into a memorandum of agreement for the exclusive license to market and perform AlloMap Molecular Expression Testing (AlloMap) in Europe.

4 Jun 2013

Scientists work together to optimize the quality, availability of fecal microbiota transplants

Monarch Labs and the BioTherapeutics, Education & Research Foundation announced today their collaboration to develop two fecal microbiota transplantation products.

4 Jun 2013

Researchers solve two longstanding challenges in liver tissue engineering

Prometheus, the mythological figure who stole fire from the gods, was punished for this theft by being bound to a rock. Each day, an eagle swept down and fed on his liver, which then grew back to be eaten again the next day.

3 Jun 2013

RBC transfusion during cardiac surgery can increase risk of postoperative infection

The risk of postoperative infection appears to increase when patients receive red blood cell (RBC) transfusion during or after cardiac surgery, and greater attention to practices that limit red blood cell use could potentially reduce the occurrence of major postoperative infections, according to a study published in the June 2013 issue of The Annals of Thoracic Surgery.

1 Jun 2013

Three easy steps for cancer survivorship

Incorporating just three easy steps into a daily routine can increase a cancer patient's chance at survival, according to a physician who specializes in cancer survivorship.

31 May 2013

Doctors perform investigational procedure on six patients using ADRCs to treat heart failure

Doctors at the Texas Heart Institute at St. Luke's Episcopal Hospital announced that they have performed an investigational procedure on six patients in a new FDA-approved clinical trial to evaluate therapy that uses regenerative cells derived from a patient's own adipose (body fat) tissue to treat a severe form of heart failure.

30 May 2013

Survival rates increased among patients who received blood stem cell transplants: Study

Survival rates have increased significantly among patients who received blood stem cell transplants from both related and unrelated donors, according to a study published in the Journal of Clinical Oncology today.

29 May 2013

Transplantation of human stem cells improves muscle function in rats used to model ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

29 May 2013

New test to predict increased risk of death, hospitalization among kidney dialysis patients

Johns Hopkins scientists report that a 10-minute test for "frailty" first designed to predict whether the elderly can withstand surgery and other physical stress could be useful in assessing the increased risk of death and frequent hospitalization among kidney dialysis patients of any age.

29 May 2013

Lab-based skin test eliminates risk of adverse reactions to new drugs, cosmetics

A simple lab-based skin test which eliminates the risk of adverse reactions to new drugs, cosmetics and household chemicals has been developed by a Newcastle University, UK team.

28 May 2013

Nephrologists rarely discuss estimates of life-expectancy with patients, study finds

Seriously ill patients undergoing hemodialysis are more optimistic about their prognosis and prospects for transplants than their nephrologists, according to a study published online by JAMA Internal Medicine.

28 May 2013

Improved communication could help with end of life decision making, suggests BIDMC research

In any given year, 400,000 Americans suffering from end-stage kidney disease will undergo dialysis, and as many as 20 to 25 percent of those dialysis patients will die, a statistic comparable to many types of cancer.

28 May 2013

Research report examines trends in pediatric organ donation and transplantation

Changes in the circumstances of when organs are donated to pediatric patients has resulted in a decreased number of organ transplant wait-list deaths over the past decade, according to research published online this week in the journal Pediatrics.

24 May 2013

OPKO reports more than 50% enrollment in phase 3 trial of Rayaldy for treatment of secondary hyperparathyroidism

OPKO Health, Inc., has surpassed 50% enrollment in the first phase 3 trial of RayaldyTM to treat patients with secondary hyperparathyroidism (SHPT), stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.

24 May 2013

Liposomal anthracycline-based chemotherapy effective for children with leukemia: Study

Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may result in high survival rates without causing any added heart toxicity, according to the results of a study published online today in Blood, the Journal of the American Society of Hematology.

24 May 2013

Takeda begins MLN9708 phase 3 clinical trial in newly diagnosed myeloma patients

Takeda Pharmaceutical Company Limited today announced the initiation of an international phase 3 clinical trial evaluating once a week MLN9708 in combination with lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma who are not candidates for transplant.

24 May 2013

Findings suggest that a prosaposin-based drug could block metastasis spread

By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces metastatic spread in mouse models of prostate, breast and lung cancer.

22 May 2013

Kidneys discarded for transplant can be used for manufacturing replacement organs, say researchers

Nearly 20 percent of kidneys that are recovered from deceased donors in the U.S. are refused for transplant due to factors ranging from scarring in small blood vessels of the kidney's filtering units to the organ going too long without blood or oxygen. But, what if instead of being discarded, these organs could be "recycled" to help solve the critical shortage of donor organs?

21 May 2013

AbbVie starts Phase 3 clinical study of atrasentan in patients with diabetic nephropathy

AbbVie announced today the initiation of a Phase 3 clinical study called SONAR (Study Of Diabetic Nephropathy with Atrasentan) to assess the effects of the investigational compound atrasentan - when added to standard of care - on progression of kidney disease in patients with stage 2 to 4 chronic kidney disease and type 2 diabetes.

21 May 2013

Transplant News and Research

Study demonstrates significant mortality rate among non-adhering heart transplant adolescent patients

Diaxonhit, XDx agree to market and perform AlloMap Molecular Expression Testing in Europe

Scientists work together to optimize the quality, availability of fecal microbiota transplants

Researchers solve two longstanding challenges in liver tissue engineering

RBC transfusion during cardiac surgery can increase risk of postoperative infection

Three easy steps for cancer survivorship

Doctors perform investigational procedure on six patients using ADRCs to treat heart failure

Survival rates increased among patients who received blood stem cell transplants: Study

Transplantation of human stem cells improves muscle function in rats used to model ALS

New test to predict increased risk of death, hospitalization among kidney dialysis patients

Lab-based skin test eliminates risk of adverse reactions to new drugs, cosmetics

Nephrologists rarely discuss estimates of life-expectancy with patients, study finds

Improved communication could help with end of life decision making, suggests BIDMC research

Research report examines trends in pediatric organ donation and transplantation

OPKO reports more than 50% enrollment in phase 3 trial of Rayaldy for treatment of secondary hyperparathyroidism

Liposomal anthracycline-based chemotherapy effective for children with leukemia: Study

Takeda begins MLN9708 phase 3 clinical trial in newly diagnosed myeloma patients

Findings suggest that a prosaposin-based drug could block metastasis spread

Kidneys discarded for transplant can be used for manufacturing replacement organs, say researchers

AbbVie starts Phase 3 clinical study of atrasentan in patients with diabetic nephropathy

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

Latest News