Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

New article provides guidance on managing critically ill patients at risk for alcohol withdrawal

Alcohol withdrawal adds challenges to caring for critically ill patients, and nurses must be diligent at each stage of care to minimize complications, according to an article in the February issue of Critical Care Nurse.

3 Feb 2016

Biochemical compound demonstrates increasing potential for use in cancer imaging

In the paper, an international team reviewed studies conducted over the past 30 years on a particular tracer, called “18F-FLT,” and found that it has the potential to improve diagnostic imaging, and thus treatment, of some cancers.

2 Feb 2016

New technology could help identify, characterize biologically active molecules produced by living cells

Gene sequencing company Illumina recently made big waves by announcing a new spinoff, Grail, dedicated to building a test for cancer by sequencing tumor DNA fragments found in blood. The company also reported plans for a separate project to identify single cells and tag them for later analysis.

1 Feb 2016

Research offers novel insights into root causes of schizophrenia

Schizophrenia is a mysterious and devastating disorder that afflicts one percent of the adult population worldwide. Its symptoms — hallucinations, emotional withdrawal, and cognitive impairment — are chronic and typically emerge just as individuals are entering adulthood. Today's medications treat just one of these symptoms (psychosis); treatments for the underlying disease and its many other symptoms have been hard to develop, because no one really understands what causes the disorder.

31 Jan 2016

New partnership aims to study underlying neurobiology and genetics of PTSD, TBI

Cohen Veterans Bioscience today announced two new collaborative partnership efforts that will provide critical research tools for understanding the underlying neurobiology and genetics of post-traumatic stress disorder (PTSD) and traumatic brain injury (TBI) with the goal of accelerating the development of first generation diagnostics and treatments.

31 Jan 2016

UCL-led researchers find way to assess viability of induced pluripotent stem cells

A research team led by scientists from UCL have found a way to assess the viability of 'manufactured' stem cells known as induced pluripotent stem cells (iPSCs). Published today in Nature Communications, the team's discovery offers a new way to fast-track screening methods used in stem cell research.

30 Jan 2016

New prognostic biomarker may help determine risk of prostate cancer-related death

Researchers at the University of Copenhagen have identified a new prognostic biomarker: the neuropeptide pro-NPY, which may help determine the risk of dying from prostate cancer. This particular type of protein is very specific to prostate cancer cells and could help identify whether newly diagnosed patients require radical prostatectomy surgery or if it is safe to delay surgery.

28 Jan 2016

Quest Diagnostics to offer in vitro diagnostic test for use in detection of PD-L1 expression for melanoma

Quest Diagnostics, the world’s leading provider of diagnostic information services, today announced it will offer clinical laboratory testing using the PD-L1 IHC 28-8 pharmDx qualitative test from Dako, an Agilent Technologies company.

From Quest Diagnostics 27 Jan 2016

ROCA Test now available in nine additional U.S. states for early detection of ovarian cancer

Abcodia, a commercial stage company focused on the development of proprietary tests for the early detection of cancer, today announced expanded U.S. availability of the ROCA Test.

26 Jan 2016

Colon cancer patients lacking CDX2 protein more likely to benefit from chemotherapy

Using a new computer science approach, researchers at University of California, San Diego School of Medicine, Columbia University and Stanford University discovered a distinctive molecular feature — a biomarker — that identified colon cancer patients who were most likely to remain disease-free up to five years after surgery.

22 Jan 2016

Researchers identify biomarkers that may influence potential new drug design or alternative treatments of cancer

Researchers have discovered gene-targets (biomarkers) that may enable alternative treatments or the potential design of new drugs that target metastasis-promoting tumor genes.

22 Jan 2016

New study identifies DKK3 as a driver of kidney fibrosis

Chronic kidney disease can develop in response to a variety of insults and is characterized by progressive renal fibrosis and atrophy of kidney tubule. Therapeutic options are limited and the disease is often not detected until later stages.

22 Jan 2016

New imaging test detects prostate cancer much better than any other tests in use today

Researchers at Thomas Jefferson University have found the method they developed to image the prostate appears to be much better at detecting prostate cancer than any other test — radiographical, biopsy or blood — in use today.

20 Jan 2016

Four USF professors selected as AIMBE College of Fellows

Four University of South Florida professors have been elected to the 2016 College of Fellows of the American Institute for Medical and Biological Engineering (AIMBE): Cesario Borlongan and Shyam Mohapatra from the USF Morsani College of Medicine, USF Health; and Robert Frisina, Jr., and Sudeep Sarkar from the USF College of Engineering.

20 Jan 2016

TG4010 vaccine promising in advanced NSCLC

Addition of the TG4010 vaccine to first-line chemotherapy improves outcomes in patients with advanced non-small-cell lung cancer, show the results of a placebo controlled trial.

19 Jan 2016

New QUiPP app could help doctors to better identify women at risk for preterm birth

A new app called QUiPP could help doctors to better identify women at risk of giving birth prematurely. The app, developed at King's College London, was tested in two studies of high-risk women being monitored at ante-natal clinics.

18 Jan 2016

Credit Value Partners closes $12.0 million DIP credit facility with Health Diagnostic Laboratory

Credit Value Partners, LP, as agent for funds and accounts under its management ("CVP"), a registered investment advisor specializing in corporate debt investments, announced that it closed a $12.0 million revolving DIP credit facility with Health Diagnostic Laboratory, Inc.

12 Jan 2016

New Qlucore Omics Explorer software aids researchers to perform deeper data analysis, biomarker discovery

Qlucore, a world leader in the development of bioinformatics software, has today unveiled Qlucore Omics Explorer 3.2, the latest version of its advanced data analysis software.

11 Jan 2016

EORTC study examines DW-MRI in patients with resectable liver metastases from colorectal cancer

Diffusion weighted (DW) magnetic resonance imaging (MRI) is a widely used technique to detect and characterize cancers as well as to monitor response to therapy. DW-MRI offers numerous advantages for patients with cancer and their treating physicians. It is a non-invasive imaging tool which does not require the administration of contrast agents nor ionizing radiation.

5 Jan 2016

Study directly links common variants of Alzheimer's risk genes to atrophy

Two genetic variants previously linked to Alzheimer's disease have been more specifically tied to brain atrophy that is characteristic of the disease.

24 Dec 2015

Biomarker News and Research

Further Reading

New article provides guidance on managing critically ill patients at risk for alcohol withdrawal

Biochemical compound demonstrates increasing potential for use in cancer imaging

New technology could help identify, characterize biologically active molecules produced by living cells

Research offers novel insights into root causes of schizophrenia

New partnership aims to study underlying neurobiology and genetics of PTSD, TBI

UCL-led researchers find way to assess viability of induced pluripotent stem cells

New prognostic biomarker may help determine risk of prostate cancer-related death

Quest Diagnostics to offer in vitro diagnostic test for use in detection of PD-L1 expression for melanoma

ROCA Test now available in nine additional U.S. states for early detection of ovarian cancer

Colon cancer patients lacking CDX2 protein more likely to benefit from chemotherapy

Researchers identify biomarkers that may influence potential new drug design or alternative treatments of cancer

New study identifies DKK3 as a driver of kidney fibrosis

New imaging test detects prostate cancer much better than any other tests in use today

Four USF professors selected as AIMBE College of Fellows

TG4010 vaccine promising in advanced NSCLC

New QUiPP app could help doctors to better identify women at risk for preterm birth

Credit Value Partners closes $12.0 million DIP credit facility with Health Diagnostic Laboratory

New Qlucore Omics Explorer software aids researchers to perform deeper data analysis, biomarker discovery

EORTC study examines DW-MRI in patients with resectable liver metastases from colorectal cancer

Study directly links common variants of Alzheimer's risk genes to atrophy

Industry Focus eBook - Protein Analysis (3rd edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo