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Noile-Immune Biotech and C4U team up to develop CRISPR/Cas3 technology

Noile-Immune Biotech Inc., ("Noile-Immune") and C4U Corporation, ("C4U") announced that they have entered into an agreement on joint research and commercialization of next-generation allogeneic gene-modified immune cell therapy combining C4U's CRISPR/Cas3 genome editing technology and Noile-Immune's PRIME (Proliferation inducing and migration enhancing) technology designed to improve proliferation and trafficking of immune cells into solid tumors.

27 Jun 2020

Interactive cloud-based data portal provides access to treasure trove of pediatric solid tumor data

An innovative, interactive cloud-based data portal debuted this week that lets academic researchers mine the world's largest and most comprehensive collection of scientific resources for studying pediatric solid tumors and their related biology.

26 Jun 2020

New rapid genomic testing can improve therapy selection for colorectal cancer patients

Genomic mutation testing is critical to therapeutic selection and management of patients with colorectal cancer. In a new multicenter study, researchers compared a new cartridge-based laboratory testing device called the Idylla automated system (Biocartis) to current standard-of-care testing methods.

26 Jun 2020

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

PrecisionLife’s unique AI platform has found 68 genes associated with risk of developing severe COVID-19 after analysis of the genomes of 929 patients from the UK Biobank who had a severe response to SARS-CoV-2.

26 Jun 2020

SARS-CoV-2 has been evolving for at least 7 years

The burning question is how novel viruses acquire the ability to recognize, bind to and enter human cells for the first time – whether this is dependent only on viral proteins recognizing host cell proteins, or adaptations in other viral processes that allow replication in a human host.

25 Jun 2020

USask researchers receive $900,000 to help strengthen Canada's rapid response to COVID-19

The Canadian Institutes of Health Research has awarded three University of Saskatchewan research teams a total of $900,000 to help strengthen Canada's rapid response to the COVID-19 pandemic which had killed more than 450,000 people worldwide.

25 Jun 2020

Single-cell sequencing method reveals possible evolutionary trajectories of cancer cells

The ability to sequence the genome of a tumor has revolutionized cancer treatment over the last 15 years by identifying drivers of cancer at the molecular level.

25 Jun 2020

Certain genes that predispose to cancer also affect the immune system, study shows

The study shows that the involvement of certain genes that predispose to cancer also affects the immune system, which could facilitate tumor growth.

25 Jun 2020

Whole genome sequencing can improve diagnosis and treatment of patients with rare diseases

A research programme pioneering the use of whole genome sequencing in the NHS has diagnosed hundreds of patients and discovered new genetic causes of disease.

24 Jun 2020

Improving cancer therapies by exploiting drug resistance in cancer

News-Medical talks to Professor David Thomas about his recent research identifying the mechanisms behind cancer cells developing resistance to drugs.

23 Jun 2020

Organoids can help provide new level of accuracy in prescribing anti-cancer therapies

Precision medicine, using the power of the human genome to diagnose and treat patients, is about to get even more precise.

22 Jun 2020

Manipulating macrophages could be a viable strategy for treating cancer

Most traditional cancer therapies target either the tumor cells themselves or indiscriminately kill any rapidly dividing cell.

22 Jun 2020

Patient genetics associated with wound microbiome composition and healing

In a first-of-its-kind study, researchers have determined that genetics may play a role in how wounds heal.

22 Jun 2020

Simple blood test found to accurately diagnose and classify brain tumors

A simple but highly sensitive blood test has been found to accurately diagnose and classify different types of brain tumors, resulting in more accurate diagnosis, less invasive methods and better treatment planning for patients, in the future.

22 Jun 2020

Killifish model helps unravel molecular events that lead to loss of protein homeostasis during brain aging

Aging is the main risk factor for dementia and Parkinson's disease. As age progresses, toxic protein aggregates pile up in the brain and impair neuronal function.

21 Jun 2020

Mutational targets of SARS-CoV-2 receptor-binding domain for vaccine-antiviral development

The COVID-19 pandemic has spread throughout the whole world within six months, causing millions of infections and hundreds of thousands of deaths. Yet there is no effective vaccine or antiviral to deal with it.

18 Jun 2020

Scientists use CRISPR tool to make rapid, precise cuts in genomic material

In a series of experiments using human cancer cell lines, scientists at Johns Hopkins Medicine say they have successfully used light as a trigger to make precise cuts in genomic material rapidly, using a molecular scalpel known as CRISPR, and observe how specialized cell proteins repair the exact spot where the gene was cut.

18 Jun 2020

New combination of biomarkers can benefit patients with advanced bladder cancer

In patients with metastatic bladder cancer, a novel combination of biomarkers from baseline tumor tissues was predictive of improved clinical responses and prolonged survival following treatment with immune checkpoint inhibitors, according to researchers from The University of Texas MD Anderson Cancer Center.

18 Jun 2020

NAU research centers receive grants from Flinn Foundation to support COVID-19 response

Scientists at two Northern Arizona University research centers--the Pathogen and Microbiome Institute and the Center for Health Equity Research--recently received grants totaling $175,000 from the Flinn Foundation in support of projects directed at responding to the COVID-19 threat.

17 Jun 2020

Even brief exposure to certain chemicals can prematurely age the liver epigenome

The epigenome is sometimes referred to as the "software" or "operating system" of the genome. It comprises small chemical modifications to DNA and the proteins that make up our chromosomes, and controls the activity of all the genes within the genome.

17 Jun 2020

Genomic News and Research

Noile-Immune Biotech and C4U team up to develop CRISPR/Cas3 technology

Interactive cloud-based data portal provides access to treasure trove of pediatric solid tumor data

New rapid genomic testing can improve therapy selection for colorectal cancer patients

PrecisionLife scientists identify 68 genes linked to severe COVID-19 risk

SARS-CoV-2 has been evolving for at least 7 years

USask researchers receive $900,000 to help strengthen Canada's rapid response to COVID-19

Single-cell sequencing method reveals possible evolutionary trajectories of cancer cells

Certain genes that predispose to cancer also affect the immune system, study shows

Whole genome sequencing can improve diagnosis and treatment of patients with rare diseases

Improving cancer therapies by exploiting drug resistance in cancer

Organoids can help provide new level of accuracy in prescribing anti-cancer therapies

Manipulating macrophages could be a viable strategy for treating cancer

Patient genetics associated with wound microbiome composition and healing

Simple blood test found to accurately diagnose and classify brain tumors

Killifish model helps unravel molecular events that lead to loss of protein homeostasis during brain aging

Mutational targets of SARS-CoV-2 receptor-binding domain for vaccine-antiviral development

Scientists use CRISPR tool to make rapid, precise cuts in genomic material

New combination of biomarkers can benefit patients with advanced bladder cancer

NAU research centers receive grants from Flinn Foundation to support COVID-19 response

Even brief exposure to certain chemicals can prematurely age the liver epigenome

Industry focus eBook: Genomics (4th edition) eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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