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Molecular action of tarantula toxin may hold clues to better control of chronic pain

Oversized, hairy tarantulas may be unsightly and venomous, but surprisingly their hunter toxin may hold answers to better control of chronic pain.

23 Nov 2020

Duke-NUS expert joins international taskforce to study the origins of SARS-CoV-2 virus

Nearly a year since the world first learned of the novel coronavirus disease 2019, COVID-19, many questions remain about SARS-CoV-2, the virus behind this pandemic: Where did it come from, how did it spread so widely and rapidly, and how can we stop similar outbreaks in the future?

23 Nov 2020

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Researchers at The University of Texas MD Anderson Cancer Center have developed a novel targeted therapy, called POMHEX, which blocks critical metabolic pathways in cancer cells with specific genetic defects.

23 Nov 2020

Chicago seroprevalence study shows COVID-19 cases 16 times higher than currently predicted

A startling new case study of Chicago, led by a team of researchers at Northwestern University in Illinois, USA, suggests a 16-fold higher incidence of SARS-CoV-2 infection than previously thought. This is judging from seroprevalence (antibody presence blood testing) figures, rather than the number of RT-PCR-positives reported there (via swab sample testing of symptomatic patients).

23 Nov 2020

Signaling pathway promotes cancer growth by blocking pro-growth signals from second major cancer pathway

Sometimes, too much of a good thing can turn out to be bad. This is certainly the case for the excessive cell growth found in cancer. But when cancers try to grow too fast, this excessive speed can cause a type of cellular ageing that actually results in arrested growth.

23 Nov 2020

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

Thanks to modern medicine, humans tend to live much longer than before. Unfortunately, this also opens a wider window to develop chronic diseases with late onset, such as neurodegenerative diseases.

23 Nov 2020

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

There is growing evidence that adipose tissue plays a key role in the aggravation of COVID-19. One of the theories under investigation is that fat cells (adipocytes) act as a reservoir for SARS-CoV-2 and increase viral load in obese or overweight individuals.

20 Nov 2020

Nursing home residents with medical order forms more likely to have preferences documented

Nursing home residents with medical order forms indicating their treatment preferences were three times more likely to have their current preferences documented in their medical record than residents without the forms, according to a study from Indiana University School of Nursing and IU Center for Aging Research at Regenstrief Institute.

20 Nov 2020

Lancaster University to help control the spread of invasive malaria mosquito

Lancaster University is involved in a major research project which aims to control the spread of an invasive malaria mosquito in Sudan and Ethiopia.

20 Nov 2020

Age is no barrier to losing weight, study shows

Obese patients over the age of 60 can lose an equivalent amount of weight as younger people using only lifestyle changes, according to a new study from the University of Warwick and University Hospitals Coventry and Warwickshire NHS Trust that demonstrates that age is no barrier to losing weight.

20 Nov 2020

Study: More investment is needed to produce, distribute approved COVID-19 vaccines

The success of a COVID-19 vaccine will depend not only on its efficacy but will hinge at least as much on how fast and widely it can be delivered, the severity of the pandemic, and the public's willingness to be immunized, according to a study published in Health Affairs.

20 Nov 2020

New findings support current and planned clinical trials of Janssen SARS-CoV-2 vaccine

Researchers from the United States and The Netherlands have conducted a pre-clinical study supporting the initiation of a Phase 3 trial to test a two-dose regimen of the Janssen Ad26.COV2.S vaccine candidate among adult and elderly individuals.

19 Nov 2020

Researchers report first spectroscopic imaging-based studies of neurological injury in COVID-19 patients

One of the first spectroscopic imaging-based studies of neurological injury in COVID-19 patients has been reported by researchers at Massachusetts General Hospital (MGH) in the American Journal of Neuroradiology.

19 Nov 2020

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Researchers at Tel Aviv University (TAU) have demonstrated that the CRISPR/Cas9 system is very effective in treating metastatic cancers, a significant step on the way to finding a cure for cancer.

19 Nov 2020

Decades of research into racial, ethnic health disparities fail to resolve disproportionate health outcomes

When it comes to understanding why children from non-white race groups have such poor health outcomes compared with their white counterparts, it's time for researchers to look beyond their genes and delve deeper into social factors, according to a commentary published today in the journal Pediatrics.

19 Nov 2020

Scientists identify previously unknown mechanism that drives tumor spread

Any given tumor is composed of a multitude of cell types that can each look or behave differently from its neighbors.

19 Nov 2020

NIH project aims to maximize efficiency of AAV platform for gene therapy

Maximizing the efficiency of the adeno-associated virus (AAV) platform for gene therapy is the aim of a new pilot project of the National Institutes of Health (NIH).

19 Nov 2020

Many hospitals across England exceeded bed occupancy thresholds during first wave of COVID-19

Thirty percent of hospitals in England reached their maximum occupancy levels for beds with mechanical ventilation support during the early stages of the Covid-19 pandemic, while the flagship Nightingale hospitals were under-utilized, according to a new study.

19 Nov 2020

Hearing loss experts urge FDA to permit the sale of OTC hearing aids

Hearing loss experts at Mass Eye and Ear are advocating for the U.S. Food and Drug Administration (FDA) to implement a law passed by Congress permitting the sale of over-the-counter (OTC) hearing aids.

19 Nov 2020

Study provides new insight into the formation of neural crest cells

Last year, researchers at the University of California, Riverside, identified the early origins of neural crest cells -- embryonic cells in vertebrates that travel throughout the body and generate many cell types -- in chick embryos.

18 Nov 2020

Medical School News and Research

Molecular action of tarantula toxin may hold clues to better control of chronic pain

Duke-NUS expert joins international taskforce to study the origins of SARS-CoV-2 virus

Novel targeted therapy blocks metabolic pathways in cancer cells with specific genetic defects

Chicago seroprevalence study shows COVID-19 cases 16 times higher than currently predicted

Signaling pathway promotes cancer growth by blocking pro-growth signals from second major cancer pathway

Researchers discover mechanism by which abnormal proteins unleash toxicity in neurodegenerative diseases

Inflammatory factors that aggravate COVID-19 may come from adipose tissue

Nursing home residents with medical order forms more likely to have preferences documented

Lancaster University to help control the spread of invasive malaria mosquito

Age is no barrier to losing weight, study shows

Study: More investment is needed to produce, distribute approved COVID-19 vaccines

New findings support current and planned clinical trials of Janssen SARS-CoV-2 vaccine

Researchers report first spectroscopic imaging-based studies of neurological injury in COVID-19 patients

CRISPR/Cas9 system is highly effective in treating metastatic cancers

Decades of research into racial, ethnic health disparities fail to resolve disproportionate health outcomes

Scientists identify previously unknown mechanism that drives tumor spread

NIH project aims to maximize efficiency of AAV platform for gene therapy

Many hospitals across England exceeded bed occupancy thresholds during first wave of COVID-19

Hearing loss experts urge FDA to permit the sale of OTC hearing aids

Study provides new insight into the formation of neural crest cells

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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