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Study determines frequency and patterns of T-cell escape mutations in HIV patients undergoing antiretroviral therapy

Immune cells that can recognize residual HIV-infected cells in people living with HIV (PLWH) who take antiretroviral therapy (ART) remain active for years, says a new study published today in eLife.

7 Oct 2020

Binge drinking is increasing, especially in women during COVID-19

Researchers last week released their work studying the pattern of alcohol use and its consequences on Americans during the ongoing COVID-19 pandemic.

6 Oct 2020

Using GWAS and trans-ancestry comparison to accurately predict risk for coronary artery disease

An international group led by researchers from the RIKEN Center for Integrative Medical Sciences have used a combination of genome-wide association analysis--or GWAS--and a trans-ancestry comparison of different GWAS studies, to come up with a more accurate predictor of coronary artery disease based on genetic factors.

6 Oct 2020

Multi-ancestry comparison can accurately predict risk factors for coronary artery disease

An international group led by researchers from the RIKEN Center for Integrative Medical Sciences have used a combination of genome-wide association analysis—or GWAS—and a trans-ancestry comparison of different GWAS studies, to come up with a more accurate predictor of coronary artery disease based on genetic factors.

6 Oct 2020

New findings could improve investigation of T cell response to COVID-19

Researchers in the United States have made an important discovery about the processing and presentation of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral peptides that provides a better understanding of the immune response to coronavirus disease 2019 (COVID-19) and may help facilitate the design of improved vaccines.

5 Oct 2020

Less than 10% of US adults have SARS-CoV-2 antibodies

A new study by researchers at Stanford University and Ascend Clinical Laboratory and published in the journal The Lancet in September 2020 reports the prevalence of antibodies to the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus in a dialysis patient population in the US.

5 Oct 2020

New tools to enhance care for brain metastases

Ambitious efforts at UVA Cancer Center to improve care delivered to patients with cancer that has spread to the brain have yielded important insights and tools that can benefit other hospitals, a new publication reports.

5 Oct 2020

Higher prevalence of SARS-CoV-2 with D614G mutation in Washington State

The study findings also indicate that the 614G viral variant is associated with higher viral load, but not with disease severity. The study is currently available on the medRxiv preprint server.

4 Oct 2020

The implications of COVID-related sexual distancing and clinical service interruption

A recent study conducted in the Atlanta area reveals that coronavirus disease 2019 (COVID-19) related sexual distancing together with clinical service interruption for sexually transmitted diseases can potentially impact the future incidence of human immunodeficiency virus (HIV) and other sexually transmitted infections (STIs). The study is currently available on the medRxiv* preprint server.

4 Oct 2020

Modeling viral clades improves prediction of COVID-19 growth rates

A new study conducted by researchers at the University of Connecticut has revealed a correlation between the prevalence of particular clades of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the growth rate of the associated illness coronavirus disease 2019 (COVID-19).

4 Oct 2020

Study shows overall rate of preoperative stress testing for hip and knee replacements

A new study out of the University of Chicago Medicine shows the overall rate of preoperative stress testing for hip and knee replacements is and has been decreasing consistently since 2006.

1 Oct 2020

Researchers identify 'social cells' in the brain linked to social behavior

A research team led by Professor TAKUMI Toru of Kobe University's Graduate School of Medicine (also a Senior Visiting Scientist at RIKEN Center for Biosystems Dynamics Research) have identified 'social cells' in the brain that are related to social behavior. The cells were identified via Ca imaging conducted using a microendoscope .

1 Oct 2020

Researchers identify a promising method to treat multiple sclerosis

Seema Tiwari-Woodruff, a professor of biomedical sciences in the School of Medicine at the University of California, Riverside, and her colleagues have received a grant of $373,000 from the National Multiple Sclerosis Society for a project in which her lab will select the five best candidate compounds to speed up nerve impulses, a promising new avenue to treat multiple sclerosis.

1 Oct 2020

Genetic heritage from Neanderthals linked to severe COVID-19

Since first appearing in late 2019, the novel virus, SARS-CoV-2, has had a range of impacts on those it infects. Some people become severely ill with COVID-19, the disease caused by the virus, and require hospitalization, whereas others have mild symptoms or are even asymptomatic.

30 Sep 2020

Singaporean study looks at WhatsApp behaviours during COVID-19 pandemic

A team of scientists from Singapore has recently studied the pattern of coronavirus disease 2019 (COVID-19) related WhatsApp usage in a group of people.

30 Sep 2020

Exosomes yield regenerative benefits equivalent to hiPSC-CCs, shows study

Science has long known that recovery from experimental heart attacks is improved by injection of a mixture of heart muscle cells, endothelial cells and smooth muscle cells, yet results have been limited by poor engraftment and retention, and researchers worry about potential tumorigenesis and heart arrhythmia.

30 Sep 2020

Generalized epilepsy patients have higher OSA risk than people with focal epilepsy

People with generalized epilepsy who have seizures arising from both sides of the brain simultaneously, have a higher risk of obstructive sleep apnea (OSA) compared to patients who have focal epilepsy where seizures emanate from one area of the brain, according to a Rutgers study.

29 Sep 2020

Valproic acid can interact with DNA conformation and regulate gene expression

Results of recent studies involving valproic acid, used for decades as an anti-convulsant drug, show that it can interact with the conformation of DNA and regulate gene expression.

29 Sep 2020

Study finds link between screen time, dietary patterns and various health behaviors

The era of the television brought with it the TV dinner -- a fast, convenient meal that, while nutritionally questionable, meant the whole family could gather together on the sofa to enjoy "The Ed Sullivan Show" and eat their Swanson Salisbury steak, too.

28 Sep 2020

Mapping the evolutionary profile of SARS-CoV-2 and COVID-19 using mutation order approach

Several months into the COVID-19 pandemic caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), we still do not know much about the early evolutionary history and order of mutational events of the virus during this pandemic.

28 Sep 2020

Frequency News and Research

Study determines frequency and patterns of T-cell escape mutations in HIV patients undergoing antiretroviral therapy

Binge drinking is increasing, especially in women during COVID-19

Using GWAS and trans-ancestry comparison to accurately predict risk for coronary artery disease

Multi-ancestry comparison can accurately predict risk factors for coronary artery disease

New findings could improve investigation of T cell response to COVID-19

Less than 10% of US adults have SARS-CoV-2 antibodies

New tools to enhance care for brain metastases

Higher prevalence of SARS-CoV-2 with D614G mutation in Washington State

The implications of COVID-related sexual distancing and clinical service interruption

Modeling viral clades improves prediction of COVID-19 growth rates

Study shows overall rate of preoperative stress testing for hip and knee replacements

Researchers identify 'social cells' in the brain linked to social behavior

Researchers identify a promising method to treat multiple sclerosis

Genetic heritage from Neanderthals linked to severe COVID-19

Singaporean study looks at WhatsApp behaviours during COVID-19 pandemic

Exosomes yield regenerative benefits equivalent to hiPSC-CCs, shows study

Generalized epilepsy patients have higher OSA risk than people with focal epilepsy

Valproic acid can interact with DNA conformation and regulate gene expression

Study finds link between screen time, dietary patterns and various health behaviors

Mapping the evolutionary profile of SARS-CoV-2 and COVID-19 using mutation order approach

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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