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People with heart disease can receive high-dose or standard-dose flu vaccines for protection

People with heart disease can receive either the high-dose or standard-dose flu vaccines for protection from heart or lung-related deaths or hospitalizations, according to late breaking research presented today at the American Heart Association's Scientific Sessions 2020.

18 Nov 2020

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

A team of researchers at the Medical University of South Carolina (MUSC) has found that the molecule lysyl oxidase (LOX) plays a number of important roles in promoting skin and organ fibrosis in scleroderma, a connective tissue disorder.

17 Nov 2020

Study finds more than half of in-hospital COVID-19 deaths among Black, Hispanic patients

More than half of all in-hospital deaths due to COVID-19 during the first six months of 2020 were among Black and Hispanic patients, according to a new study led by researchers at the Stanford University School of Medicine and Duke University.

17 Nov 2020

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

Researchers affiliated with the Center for Cell-Based Therapy in Ribeirão Preto, Brazil, have identified for the first time a non-hereditary mutation in blood cells from a patient with GATA2 deficiency, a rare autosomal disease caused by inherited mutations in the gene that encodes GATA-binding protein 2 (GATA2).

17 Nov 2020

Stronger relationships between nursing homes and health systems can enhance patient care

In a new editorial in the Journal of the American Geriatrics Society, Kathleen Unroe, M.D., MHA, a geriatrician, is advocating for stronger relationships between health systems and nursing homes to provide better care for patients in times of crisis and during day-to-day operations.

17 Nov 2020

New program can remotely improve cardiovascular health for broad population of patients

Despite being known risk factors for poor cardiovascular outcomes, blood pressure and low-density lipoprotein (LDL) cholesterol remain undertreated among a large proportion of patients.

17 Nov 2020

Study examines healthy food labels that work and don't work

Want that packet of biscuits? That'll be 17 minutes of jogging to burn off one serving (and there's probably more than one serving in there).

17 Nov 2020

Novel drug reduces the risk of cardiovascular events for patients with Type 2 diabetes, kidney disease

A novel diabetes medication significantly reduces the risk of hospitalization for heart failure, heart attack and stroke, in patients with Type 2 diabetes and chronic kidney disease, according to late breaking research presented today at the American Heart Association's Scientific Sessions 2020.

17 Nov 2020

Discovery of 'Achilles heel' in protein crucial to HIV virulence could lead to new class of drugs

The discovery of a potential "Achilles heel" in Nef, the protein that is crucial to HIV virulence and its capacity to trigger AIDS, paves the way for the development of a new class of drugs against the virus.

17 Nov 2020

Clinical trials show SGLT2 inhibitor may benefit patients with type 2 diabetes

Less than a decade ago, the Food and Drug Administration approved drugs for treating type 2 diabetes in an entirely new way.

16 Nov 2020

Study shows limited influence of BMI on shaping SARS-CoV-2 antibody responses

A new study by researchers at the Harvard Medical School and the Ragon Institute of MGH, MIT and Harvard showed that obesity is not tied to the increased risk of SARS-CoV-2 infection. However, the team demonstrated that obesity is associated with increased manifestations of symptoms in mild COVID-19 infections, suggesting that obesity impacts the pathophysiology of COVID-19.

16 Nov 2020

Short bursts of exercise elicit widespread changes in the body's levels of metabolites

Short bursts of physical exercise induce changes in the body's levels of metabolites that correlate to, and may help gauge, an individual's cardiometabolic, cardiovascular and long-term health, a study by Massachusetts General Hospital has found.

16 Nov 2020

Health care workers have a higher prevalence of COVID-19 than non-health care workers

Health care workers -- particularly nurses -- have a higher prevalence of SARS-CoV-2 infection than non-health care workers, according to researchers at Rutgers, which released baseline results from a large prospective study of participants at Rutgers and affiliated hospitals recruited during the early phase of the COVID-19 pandemic.

16 Nov 2020

Modifiable risk factors in the first 1000 days of life predict higher adiposity and cardiometabolic risk

Early life risk factors in the first 1000 days cumulatively predict higher obesity and cardiometabolic risk in early adolescence, according to new research led by the Harvard Pilgrim Health Care Institute.

16 Nov 2020

Study could pave the way for potential urine test to diagnose liver fibrosis

Fifty fragments of proteins, termed peptides, have been identified in the urine of liver fibrosis patients in a new study that could pave the way for a potential diagnostic urine test for the condition if further validated.

16 Nov 2020

CEAT project for improving ovarian cancer diagnosis, treatment shows promise

Porvair Sciences reports, due to promising results, it has agreed with its collaborative partners to make additional investment in the CEAT project which aims to dramatically improve the diagnosis and treatment of ovarian cancer.

From Porvair Sciences Limited 16 Nov 2020

New drug reduces LDL cholesterol in patients with severe hypercholesterolemia

The investigational drug evinacumab reduced low-density lipoprotein (LDL) cholesterol--the so-called "bad" cholesterol--by 50 percent in patients with severe hypercholesterolemia whose condition is resistant to standard treatments, a phase 2 study from the Icahn School of Medicine of Mount Sinai and other global academic sites has found.

16 Nov 2020

New data highlights safety concerns on rAAV vectors used in gene therapy

New data highlight safety concerns for the replication of recombinant adeno-associated viral (rAAV) vectors commonly used in gene therapy.

16 Nov 2020

Community-wide resuscitation program demonstrates 100% success rate in cannulation

Published today in the EClinicalMedicine Journal, a study from the University of Minnesota found that the first four months of the Minnesota Mobile Resuscitation Consortium (MMRC) was 100% effective in cannulation for out-of-hospital sudden cardiac arrests.

15 Nov 2020

Promising new compounds to potentially treat novel coronaviruses identified

Researchers at the University of Maryland School of Medicine and School of Pharmacy have discovered new drug compounds to potentially treat the novel coronavirus that causes COVID-19.

15 Nov 2020

Medical School News and Research

People with heart disease can receive high-dose or standard-dose flu vaccines for protection

LOX plays a number of key roles in promoting skin and organ fibrosis in scleroderma

Study finds more than half of in-hospital COVID-19 deaths among Black, Hispanic patients

Somatic mutation may act as a natural gene therapy in patients with rare autosomal disease

Stronger relationships between nursing homes and health systems can enhance patient care

New program can remotely improve cardiovascular health for broad population of patients

Study examines healthy food labels that work and don't work

Novel drug reduces the risk of cardiovascular events for patients with Type 2 diabetes, kidney disease

Discovery of 'Achilles heel' in protein crucial to HIV virulence could lead to new class of drugs

Clinical trials show SGLT2 inhibitor may benefit patients with type 2 diabetes

Study shows limited influence of BMI on shaping SARS-CoV-2 antibody responses

Short bursts of exercise elicit widespread changes in the body's levels of metabolites

Health care workers have a higher prevalence of COVID-19 than non-health care workers

Modifiable risk factors in the first 1000 days of life predict higher adiposity and cardiometabolic risk

Study could pave the way for potential urine test to diagnose liver fibrosis

CEAT project for improving ovarian cancer diagnosis, treatment shows promise

New drug reduces LDL cholesterol in patients with severe hypercholesterolemia

New data highlights safety concerns on rAAV vectors used in gene therapy

Community-wide resuscitation program demonstrates 100% success rate in cannulation

Promising new compounds to potentially treat novel coronaviruses identified

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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