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Low or high levels of hemoglobin may increase risk of dementia

Having either low or high levels of hemoglobin in your blood may be linked to an increased risk of developing dementia years later, according to a study published in the July 31, 2019, online issue of Neurology, the medical journal of the American Academy of Neurology.

1 Aug 2019

Propranolol's target in treating rare vascular syndrome and hemangioma discovered

The discovery of a new target for the blood-pressure medication propranolol may lead to the development of new and safer therapies for vascular diseases, according to new findings published in eLife.

31 Jul 2019

Stem cell study provides insight into development, maintenance of the skin

For the first time, researchers from the University of Copenhagen have studied and outlined the development of sebaceous glands in the skin. The study provides greater insight into the development and maintenance of the skin and how cancer mutations affect the behavior of stem cells.

30 Jul 2019

Cigarette smoke can make MRSA bacterium more resistant to antibiotics

Cigarette smoke can make MRSA bacterial strains more resistant to antibiotics, new research from the University of Bath has shown.

30 Jul 2019

Study finds specific direct targets for lung cancer treatment

A team of researchers at the Salk Institute has found two therapeutic targets for the deadly type of lung cancer, non-small-cell lung carcinomas (NSCLCs), which accounts for 85 percent of all lung cancer cases. They believe that the breakthrough discovery could pave the way for the development of new treatments for a majority of lung cancer patients.

29 Jul 2019

Scientists reverse social traits associated with autism in mouse model

Research has been ongoing in the field of genetic mutations and changes and brain and other neural disorders including Autism Spectrum Disorders (ASD) and a new study in mice models of autism has shown a possible link between mutations or deletions of the SHANK3 gene and a rare disorder called Phelan-McDermid syndrome and ASD.

29 Jul 2019

Whole genome sequencing reveals role of CNVs in insecticide resistance in malaria mosquitoes

Researchers from LSTM, working alongside colleagues from the Wellcome Sanger Institute, Cambridge and the Big Data Institute, University of Oxford, have used whole genome sequencing to understand copy-number variants (CNVs) in malaria mosquitoes and their role in insecticide resistance.

27 Jul 2019

Genetic mutations link rare skin disorder and non-alcoholic fatty liver disease

Fatty liver disease is often associated with alcoholism, but more than a third of Americans have fatty livers despite moderate or absent alcohol consumption.

25 Jul 2019

Research links inherited BRCA2 mutations with increased risk of childhood lymphoma

A report from St. Jude Children's Research Hospital links inherited mutations in the BRCA2 gene with an increased risk of developing non-Hodgkin lymphoma in children and adolescents.

25 Jul 2019

Researchers explore stem cells for answers to how fragile X syndrome develops

The lab of Yongchao Ma, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago, discovered how the genetic defect in fragile X syndrome – a type of autism – delays production of neurons (nerve cells) at a critical time in the embryo's brain development.

24 Jul 2019

Brain protein mutation from an autistic person alters behavior in mice

A de novo gene mutation that encodes a brain protein in a child with autism has been placed into the brains of mice.

24 Jul 2019

Women who inherit BRCA mutations have high risk of developing cancer

Women who inherit harmful mutations in the BRCA1 or BRCA2 gene are at high risk of developing breast and ovarian cancer.

24 Jul 2019

Gene mutation in the brain of autism patients alters behaviors in mice

Autism spectrum disorder (ASD) has a wide range of possible causes, including genetics and environmental factors. Now, a new study suggests that a brain protein mutation may shed light on the mechanism of neurological and developmental illness.

23 Jul 2019

Exosomes can restore health to brain cells affected by developmental disease

Like overpacked suitcases unloaded from the underbelly of a jet, molecular satchels called exosomes are continuously deployed from all cells in the body—each one brimming with an assortment of contents that another cell may unpack and use.

23 Jul 2019

Evolutionary gene loss may explain heightened risk of cardiovascular disease in humans

Researchers at University of California San Diego School of Medicine say the loss of a single gene two to three million years ago in our ancestors may have resulted in a heightened risk of cardiovascular disease in all humans as a species, while also setting up a further risk for red meat-eating humans.

23 Jul 2019

New technology helps develop more personalized treatments for patients with advanced cancers

Being able to identify targets for adoptive cell therapies is one of the first steps in developing personalized treatments for people with hard-to-treat cancers.

22 Jul 2019

Genetic similarities of deadly bone cancer between dogs and children revealed

A bone cancer known as osteosarcoma is genetically similar in dogs and human children, according to the results of a study published today by Tufts University and the Translational Genomics Research Institute, an affiliate of City of Hope.

21 Jul 2019

Group of genes linked to longer lifespan in fruit flies discovered

Alexey Moskalev, Ph.D., Head of the Laboratory of Geroprotective and Radioprotective technologies, and co-authors from the Institute of biology of Komi Science Center of RAS, the Engelgard's Institute of molecular biology of RAS and Moscow Institute of Physics and Technology published a scientific article titled "Transcriptome Analysis of Long-lived Drosophila melanogaster E(z) Mutants Sheds Light on the Molecular Mechanisms of Longevity" in Nature Scientific Reports - the leading international multidisciplinary weekly journal.

19 Jul 2019

Researchers identify brain somatic mutations linked to Alzheimer's disease

Researchers have identified somatic mutations in the brain that could contribute to the development of Alzheimer's disease. Their findings were published in the journal Nature Communications last week.

18 Jul 2019

Researchers develop a more precise version of CRISPR-Cas9 gene-editing system

A gene defect in humans causes progressive hearing loss in humans, resulting in deafness by their mid-20s. The same genetic mutation causes deafness in the Beethoven-mouse model.

18 Jul 2019