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Study links menopause hormone therapy to varied heart and blood clot risks

Research on hormone therapy reveals critical insights into cardiovascular disease risks, guiding clinicians in selecting safer treatment options for menopause.

3 Dec 2024

Overcoming challenges in developing cell therapies for heart disease

Pathways to new treatments for heart failure take time - as long as four decades for two now accepted therapies. So, new attempts to repair scar tissue in infarcted hearts using cells or cell products need more time to develop clinical therapies that can reduce risk of death from heart failure after a heart attack.

3 Dec 2024

New food-grade natural solution created for tackling obesity

As obesity rates continue to rise, many are turning to prescription medicines like Ozempic for weight loss. But with significant side effects, accessibility and cost issues, alternatives are needed.

2 Dec 2024

Disrupted sleep patterns identified in patients with metabolic dysfunction-associated steatotic liver disease

The prevalence of MASLD (metabolic dysfunction-associated steatotic liver disease) is exploding in most regions of the world, boosted by increased obesity and sedentary lifestyles.

2 Dec 2024

Hypothalamic deep brain stimulation restores walking after spinal cord injury

Scientists have identified neurons in the lateral hypothalamus that can be targeted through deep brain stimulation to improve walking after spinal cord injury (SCI). This innovative approach shows promise in both animal models and initial human trials, paving the way for groundbreaking treatments.

2 Dec 2024

Understanding the role of sleep in dementia and associated illnesses

A new review was published on the cover of Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 16, Issue 21, titled, "Sleep deprivation in dementia comorbidities: focus on cardiovascular disease, diabetes, anxiety/depression and thyroid disorders."

2 Dec 2024

Hypothalamic DBS therapy improves recovery of lower limb movements after spinal cord injury

Researchers at EPFL and Lausanne University Hospital (CHUV), led by professors Grégoire Courtine and Jocelyne Bloch, have achieved a major milestone in the treatment of spinal cord injuries (SCI).

2 Dec 2024

New study explores heart risks of cancer immunotherapy

A cancer therapy that prompts the body's immune defenses against viruses and bacteria to attack tumors can make patients more vulnerable to heart attack and stroke.

2 Dec 2024

Beta-blocker drugs may slow Huntington's disease progression

A common heart drug may slow the progression of Huntington's disease (HD), according to a new study by University of Iowa Health Care researchers.

2 Dec 2024

IL-15 improves the effectiveness of GPC3 CAR T cells in targeting solid tumors

The study reveals IL-15's role in enhancing GPC3 CAR T cell therapy, improving tumor targeting and T cell survival in patients with solid cancers.

2 Dec 2024

New study explores obecabtagene autoleucel for adults with hard-to-treat leukemia

FELIX study results reveal obe-cel's potential in relapsed B-cell ALL, achieving 77% remission with low severe toxicity, enhancing CAR T-cell therapy outcomes.

2 Dec 2024

Homebound seniors living alone often slip through health system’s cracks

Carolyn Dickens, 76, was sitting at her dining room table, struggling to catch her breath as her physician looked on with concern.

2 Dec 2024

Neural connectivity predicts deep brain stimulation success in essential tremor

Study unveils how specific cortico-thalamic connectivity patterns influence essential tremor suppression with deep brain stimulation (DBS). It highlights the contralateral thalamus as a pivotal driver of tremor modulation and potential pathways for enhanced intervention strategies.

1 Dec 2024

Quabodepistat combo shows promise for safer, faster tuberculosis treatment

Study highlights the safety and early bactericidal activity of quabodepistat when combined with delamanid, bedaquiline, or both, offering potential for shorter and more tolerable tuberculosis treatment regimens.

1 Dec 2024

Phase 1 study finds serine- and glycine-free diet boosts immune response in colorectal cancer

Findings indicate a serine/glycine-free diet can reduce colorectal cancer growth and enhance immune response, offering insights for immunotherapy strategies.

29 Nov 2024

Scientists identify drug-resistant bone marrow cells linked to poor outcomes in fast-growing leukemia

Researchers explore treatment resistance and relapse in T-cell acute lymphoblastic leukemia.

29 Nov 2024

STAG2 loss linked to increased aggression in Ewing sarcoma

Ewing sarcoma is a tumor of the bones and soft tissues that occurs in children and young people. Like all childhood cancers, it is rare – 9 to 10 cases per million inhabitants per year – but it is very aggressive. 25% of patients do not respond well to regular therapy and they often experience relapses.

29 Nov 2024

Research highlights long-term health effects of hormone therapy in transgender individuals

New research from Karolinska Institutet shows that long-term sex hormone treatment in transgender individuals can lead to significant changes in body composition and risk factors for cardiovascular disease, particularly in transgender men.

28 Nov 2024

Study reveals varied risks of hormone treatments for menopausal symptoms

Researchers at Uppsala University have analyzed the effects of seven different hormone treatments for menopausal symptoms on the risk of blood clots, stroke and heart attack.

28 Nov 2024

Specific HRT tablets linked to increased risk of heart disease and blood clots

Certain hormone replacement therapy (HRT) tablets containing both estrogen and progestogen are associated with a higher risk of heart disease and rare but serious blood clots known as venous thromboembolism (VTE) in women around the age of menopause, finds a study from Sweden published by The BMJ today.

28 Nov 2024