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‘Window for intervention’ to forestall hypertensive cognitive decline

Newly diagnosed hypertension is predictive of cognitive decline in middle-aged individuals and is worse in those with poorly controlled blood pressure, Dutch researchers have found.

16 Dec 2013

BioLineRx reports promising initial results from Phase 2 trial of BL-8040 in AML patients

BioLineRx, a clinical-stage biopharmaceutical company dedicated to identifying, in-licensing and developing promising therapeutic candidates, announced today promising initial results for its BL-8040 drug candidate in a Phase 2 clinical trial for patients with relapsed or refractory acute myeloid leukemia (AML).

16 Dec 2013

MicroBiome Therapeutics announces completion of $1.3M bridge financing

MicroBiome TherapeuticsTM LLC, today announced completion of a $1.3 million bridge financing. It is intended to support completion of the company's two ongoing clinical studies and preparations for further clinical trials of lead product NM504, a microbiome modulator in development for type 2 diabetes and prediabetes. The bridge financing was led by current investor BVM Capital, who was joined in the round by other existing MBT investors.

16 Dec 2013

Two UTHealth professors elected fellows of American Association for the Advancement of Science

Two professors at The University of Texas Health Science Center at Houston - Barry Davis, M.D., Ph.D., and Kevin Morano, Ph.D. - have been elected fellows into the American Association for the Advancement of Science, the world's largest general scientific society and publisher of the journal Science.

16 Dec 2013

Better to fat finger a text than to lose a finger due to the cold

The popular half-gloves that leave fingers uncovered for texting may be good for communicating electronically but they may also lead to permanent loss of fingers due to exposure to the cold. "Fingers are one of the first body parts to feel the effects of the cold and damp and along with toes, ears and the nose are frequently subjected to frostbite and even amputation," says Arthur Sanford, MD, Division of Trauma, Surgical Critical Care and Burns, Loyola University Health System.

16 Dec 2013

Stem cell technology: an interview with Professor Igor Slukvin, University of Wisconsin-Madison and scientific founder of CDI and Cynata

Stem cells have a potential to develop into multiple cell types and divide without limit to replenish cells in human body throughout the life of individual.

16 Dec 2013

Janssen receives complete response letter for canagliflozin/metformin FDC therapy for type 2 diabetes

Janssen Research & Development, LLC (Janssen) today announced it has received from the U.S. Food and Drug Administration (FDA) a complete response letter regarding its New Drug Application (NDA) for a fixed-dose combination (FDC) of canagliflozin and immediate-release metformin to treat adults with type 2 diabetes.

16 Dec 2013

Switching chemotherapy does not improve survival in metastatic breast cancer patients with CTCs

For women with metastatic breast cancer who had elevated amounts of circulating tumor cells (CTCs) in their blood after a first line of chemotherapy, switching immediately to a different chemotherapy did not improve overall survival or time to progression, according to the results of a phase III clinical trial presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

16 Dec 2013

NTU researchers find way to block invasion of Malaria parasite in blood cells

Scientists from Singapore's Nanyang Technological University have discovered a key process during the invasion of the blood cell by the Malaria parasite, and more importantly, found a way to block this invasion.

16 Dec 2013

Red state residents enrolling in Obamacare at lower rates

People in GOP-controlled states are signing up for coverage in the health law's exchanges at lower rates than those in blue states, reports the Associated Press. Meanwhile, news outlets offer snapshots of how signups are going in Montana, Wyoming, Connecticut, Colorado, Oregon and Washington state.

16 Dec 2013

NIH Stroke Trials Network includes UC San Diego Health System as grant recipient

A network of 25 nationally recognized stroke centers has been created to rapidly address the three core features of stroke research and care: prevention, treatment and recovery. The regional coordinating centers, working with nearby satellite facilities, will span the country and have teams of researchers representing every stroke-related medical specialty, with the primary goal of bringing new therapies and strategies to the stroke community more rapidly.

16 Dec 2013

Combination of ramucirumab and docetaxel fails to delay advanced breast cancer progression

Adding the antibody therapy ramucirumab to the chemotherapy drug docetaxel did not delay disease progression for patients with HER2-negative, advanced breast cancer, according to results of a placebo-controlled, randomized, phase III clinical trial presented here at the 2013 San Antonio Breast Cancer Symposium, held Dec. 10-14.

16 Dec 2013

Researchers gather first direct evidence of how microbubbles cause blood clot's demise

Ultrasound-stimulated microbubbles have been showing promise in recent years as a non-invasive way to break up dangerous blood clots. But though many researchers have studied the effectiveness of this technique, not much was understood about why it works. Now a team of researchers in Toronto has collected the first direct evidence showing how these wiggling microbubbles cause a blood clot's demise. The team's findings are featured in the AIP Publishing journal Applied Physics Letters.

16 Dec 2013

Cornell engineers create smartCARD that uses smartphone's camera to read cholesterol level

With a new smartphone device, you can now take an accurate iPhone camera selfie that could save your life - it reads your cholesterol level in about a minute.

16 Dec 2013

Cancer cells that fuse with macrophages play key role in the spread of cancer

Cancer cells that spontaneously fuse with macrophages, the immune system's healthy scavenger cells, play a key role in the metastasis, or spread of the cancer to other areas of the body, according to research to be presented Sunday, Dec. 15, at the American Society for Cell Biology annual meeting in New Orleans.

16 Dec 2013

Blending more ethanol into fuel to reduce air pollution carries hidden risk

Blending more ethanol into fuel to cut air pollution from vehicles carries a hidden risk that toxic or even explosive gases may find their way into buildings, according to researchers at Rice University.

15 Dec 2013

Daily exercise lessens harmful physiological effects of short-term overeating, inactivity, says study

Daily exercise lessens many of the harmful physiological effects of short-term overeating and inactivity, shows a new study [published 15 December] in The Journal of Physiology, which is well timed with the Christmas holiday approaching.

15 Dec 2013

Possible mechanism behind elevated risk of cardiovascular disease discovered in HIV-infected women

A Massachusetts General Hospital research team has discovered a possible mechanism behind the elevated risk of cardiovascular disease in women infected with HIV, a risk even higher than that of HIV-infected men. In the Dec. 1 issue of the Journal of Infectious Diseases the investigators report finding that HIV-infected women had a greater prevalence of the type of coronary artery plaque most vulnerable to rupture than did uninfected women.

14 Dec 2013

Study: Brain blood vessel cells may be therapeutic targets for Alzheimer's disease

A study in mice shows how a breakdown of the brain's blood vessels may amplify or cause problems associated with Alzheimer's disease. The results published in Nature Communications suggest that blood vessel cells called pericytes may provide novel targets for treatments and diagnoses.

14 Dec 2013

New UCSF-led study links obesity to development of chronic kidney disease

A new UCSF-led study of nearly 3,000 individuals links obesity to the development of kidney disease. The work also shows that, when properly measured, declines in kidney function are detectable long before the emergence of other obesity-related diseases such as diabetes and high blood pressure.

14 Dec 2013

Blood News and Research

‘Window for intervention’ to forestall hypertensive cognitive decline

BioLineRx reports promising initial results from Phase 2 trial of BL-8040 in AML patients

MicroBiome Therapeutics announces completion of $1.3M bridge financing

Two UTHealth professors elected fellows of American Association for the Advancement of Science

Better to fat finger a text than to lose a finger due to the cold

Stem cell technology: an interview with Professor Igor Slukvin, University of Wisconsin-Madison and scientific founder of CDI and Cynata

Janssen receives complete response letter for canagliflozin/metformin FDC therapy for type 2 diabetes

Switching chemotherapy does not improve survival in metastatic breast cancer patients with CTCs

NTU researchers find way to block invasion of Malaria parasite in blood cells

Red state residents enrolling in Obamacare at lower rates

NIH Stroke Trials Network includes UC San Diego Health System as grant recipient

Combination of ramucirumab and docetaxel fails to delay advanced breast cancer progression

Researchers gather first direct evidence of how microbubbles cause blood clot's demise

Cornell engineers create smartCARD that uses smartphone's camera to read cholesterol level

Cancer cells that fuse with macrophages play key role in the spread of cancer

Blending more ethanol into fuel to reduce air pollution carries hidden risk

Daily exercise lessens harmful physiological effects of short-term overeating, inactivity, says study

Possible mechanism behind elevated risk of cardiovascular disease discovered in HIV-infected women

Study: Brain blood vessel cells may be therapeutic targets for Alzheimer's disease

New UCSF-led study links obesity to development of chronic kidney disease

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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