Genes News and Research

RSS

Scientists identify mutations in 11 genes associated with aggressive forms of prostate cancer

An international research team led by scientists in the Center for Genetic Epidemiology at the Keck School of Medicine of USC and USC Norris Comprehensive Cancer Center has singled out mutations in 11 genes that are associated with aggressive forms of prostate cancer.

21 Sep 2023

New method detects microRNA targets at the level of single cells

MicroRNAs are small molecules that regulate gene activity by binding to and destroying RNAs produced by the genes.

21 Sep 2023

Study sheds light on the cause of craniosynostosis in infants

Craniosynostosis, the premature fusion of the top of the skull in infants, is caused by an abnormal excess of a previously unknown type of bone-forming stem cell, according to a preclinical study led by researchers at Weill Cornell Medicine.

21 Sep 2023

Manipulating mitochondrial electron flow enhances immune response, reduces tumor growth

Immunotherapy, which uses the body's own immune system to fight cancer, is an effective treatment option, yet many patients do not respond to it.

21 Sep 2023

Compound found in hops can combat metabolic syndrome by reducing Oscillibacter population

Researchers have shown in a mouse model and lab cultures that a compound derived from hops reduces the abundance of a gut bacterium associated with metabolic syndrome.

21 Sep 2023

AlphaMissense revolutionizes genetic mutation analysis for disease prediction

AlphaMissense, an adaptation of AlphaFold, offers a highly accurate model for predicting the pathogenicity of human proteome-wide missense variants at the single amino acid level. The model outperforms existing methods, providing valuable insights for diagnosing rare diseases and developing targeted therapies.

20 Sep 2023

Creating CAR-T cells with enhanced immune memory to fight cancer

Among available immunotherapies, the use of «CAR-T» cells is proving extremely effective against certain blood cancers, but only in half of patients.

20 Sep 2023

Doctors need better guidance on treating ADHD in over 50s

Doctors urgently need better international guidance on treating attention deficit hyperactivity disorder (ADHD) in the over 50s, conclude world-leading experts reviewing current research on this increasing issue globally.

20 Sep 2023

Newborn screening for neurodevelopmental disorders may cause more harm than good

Expanding newborn screening (NBS) to include identifying genes associated with an increased risk for neurodevelopmental disorders (NDD) would cause more harm than good, according to an article published in Pediatrics.

20 Sep 2023

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

A team of Dana-Farber researchers has identified a potential new way to assess clinically valuable features of clear cell renal cell carcinoma (ccRCC), a form of kidney cancer, using image processing with deep learning.

20 Sep 2023

Unlocking the potential of the ketogenic diet: studies reveal health benefits

Researchers reported on the effects of the ketogenic diet (KD) on various aspects of metabolic and endocrinal health.

20 Sep 2023

New study sheds light on vitamin D's role in cardiovascular health

Researchers conducted a prospective population-based analysis to understand whether vitamin D levels were associated with cardiovascular disease events and mortality, and overall mortality.

20 Sep 2023

Game-changing point-of-care assay could revolutionize Mpox detection worldwide

Researchers developed a point-of-care assay for the rapid detection of mpox virus.

20 Sep 2023

Subclonal neoantigens present a key roadblock in MMRd tumor immunotherapy success

Researchers evaluated sensitivity to immune checkpoint blockade (ICB) therapy.

20 Sep 2023

DeepMind develops new tool to predict pathogenicity of missense variants

DeepMind is releasing AlphaMissense, a tool researchers can use to learn more about the effects that missense mutations – which make up the majority of "variants of uncertain significance" – have on disease.

19 Sep 2023

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

Regular and intense aerobic exercise may reduce the risk of colorectal cancer in patients with Lynch Syndrome (LS) by improving the immune system's ability to detect and remove potentially harmful cells, according to researchers at The University of Texas MD Anderson Cancer Center.

19 Sep 2023

Study offers new insight into increased risk of blood clots in women

New research from Queen Mary University of London, published in iScience, shows an increased risk of blood clots in women who have any combination of a particular gene mutation, estrogen use, or common medical conditions - specifically: obesity, high blood pressure, high cholesterol, and kidney disease.

19 Sep 2023

Scientists uncover potential key risk factors for melanomas in children and adolescents

A recent eBioMedicine study found key risk factors associated with the development of melanoma in children and adolescents.

19 Sep 2023

Ongoing gene therapy trials have driven increased use of ALS genetic testing, finds study

Researchers at The Ohio State University Wexner Medical Center and College of Medicine led the creation of evidence-based consensus guidelines for genetic testing and counseling for patients with amyotrophic lateral sclerosis (ALS), a neurodegenerative disease that affects the cells in the brain and spine.

19 Sep 2023

New research offers insight about the reason mitochondrial DNA is maternally inherited

New research provides insight about the bedrock scientific principle that mitochondrial DNA - the distinct genetic code embedded in the organelle that serves as the powerplant of every cell in the body - is exclusively passed down by the mother.

19 Sep 2023

Genes News and Research

Scientists identify mutations in 11 genes associated with aggressive forms of prostate cancer

New method detects microRNA targets at the level of single cells

Study sheds light on the cause of craniosynostosis in infants

Manipulating mitochondrial electron flow enhances immune response, reduces tumor growth

Compound found in hops can combat metabolic syndrome by reducing Oscillibacter population

AlphaMissense revolutionizes genetic mutation analysis for disease prediction

Creating CAR-T cells with enhanced immune memory to fight cancer

Doctors need better guidance on treating ADHD in over 50s

Newborn screening for neurodevelopmental disorders may cause more harm than good

AI-based tool can assess pathology slides to identify valuable features of clear cell renal cell carcinoma

Unlocking the potential of the ketogenic diet: studies reveal health benefits

New study sheds light on vitamin D's role in cardiovascular health

Game-changing point-of-care assay could revolutionize Mpox detection worldwide

Subclonal neoantigens present a key roadblock in MMRd tumor immunotherapy success

DeepMind develops new tool to predict pathogenicity of missense variants

High-intensity exercise may reduce colorectal cancer risk in Lynch Syndrome patients

Study offers new insight into increased risk of blood clots in women

Scientists uncover potential key risk factors for melanomas in children and adolescents

Ongoing gene therapy trials have driven increased use of ALS genetic testing, finds study

New research offers insight about the reason mitochondrial DNA is maternally inherited

eBook: Using iPSCs models for human disease research and drug discovery eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo