Infectious Diseases News and Research

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Protein uses two different mechanisms to inhibit viral infections

To protect humans against infection, a protein called MARCH8 tags the vesicular stomatitis virus (VSV) for destruction while it merely holds HIV hostage, a new study in eLife shows.

11 Aug 2020

Public health officials are quitting or getting fired in throes of pandemic

Vilified, threatened with violence or in some cases suffering from burnout, dozens of state and local public health officials around the U.S. have resigned or have been fired amid the coronavirus outbreak, a testament to how politically combustible masks, lockdowns and infection data have become.

11 Aug 2020

Finland joins international organization dedicated to COVID-19 vaccines

The flag of Finland was raised at the International Vaccine Institute (IVI) Headquarters today during a ceremony welcoming the country's accession to IVI.

11 Aug 2020

Specific HIV and tuberculosis medications decrease risk of death in adults with drug-resistant TB

After looking at the health records of over 10,000 patients with both HIV and multidrug resistant Tuberculosis (TB) in over 20 different countries, researchers at the Perelman School of Medicine at the University of Pennsylvania in collaboration with the Centers for Disease Control and Prevention, McGill University, and other institutions around the world, found that implementing antiretroviral therapy (ART) for HIV and newer tuberculosis medications decreased the risk of death for adults with drug-resistant TB.

11 Aug 2020

COVID-19 Prevention Network announces Phase 3 trials to evaluate monoclonal antibodies

The COVID-19 Prevention Network (CoVPN) today announced two Phase 3 trials to determine whether monoclonal antibodies (mAbs) can prevent SARS-CoV-2, the virus that causes COVID-19.

11 Aug 2020

One-third of children hospitalized with COVID-19 admitted to ICU, study finds

Now, new research has found that children are still at a high risk of developing severe COVID-19. The study shows that one-third of children hospitalized due to COVID-19 were admitted to intensive care units (ICU), a rate similar to adults.

11 Aug 2020

Baylor Scott & White Research Institute enrolls first patients in NIH ACTIV-3 clinical trial

On Wednesday, August 5, in Dallas, just one day after the initiative was launched by the National Institutes of Health, Baylor Scott & White Research Institute enrolled the first patient in the world for the ACTIV-3 clinical trial. A second patient was enrolled the following day.

10 Aug 2020

Mouthwashes could lower the transmission of SARS-CoV-2

Sars-Cov-2 viruses can be inactivated using certain commercially available mouthwashes. This was demonstrated in cell culture experiments by virologists from Ruhr-Universität Bochum together with colleagues from Jena, Ulm, Duisburg-Essen, Nuremberg and Bremen. High viral loads can be detected in the oral cavity and throat of some Covid-19 patients.

10 Aug 2020

Speed of Novavax vaccine development does not compromise quality of the SARS-CoV-2 immunogen

A new study by researchers from the Scripps Research Institute and Novavax Inc. in the US affirms the structural integrity of the full-length SARS-CoV-2 spike glycoprotein immunogen. It enables the interpretation of immune responses to this multivalent nanoparticle immunogen. Their results are currently available on bioRxiv preprint server.

9 Aug 2020

Study identifies five immune response markers that may predict COVID-19 patient outcomes

Galit Alter, PhD, Group Leader at the Ragon Institute of MGH, MIT and Harvard and Professor of Medicine at Harvard Medical School, and Helen Chu, MD, Associate Professor of Medicine, Division of Allergy and Infectious Diseases, University of Washington School of Medicine, and UW Medicine physician, have recently published a paper which identifies five immune response markers which, collectively, were able to correctly classify both convalescent COVID-19 patients and those who did not survive the disease.

7 Aug 2020

New test can pinpoint which people with gonorrhea can be cured with ciprofloxacin

A test designed by UCLA researchers can pinpoint which people with gonorrhea will respond successfully to the inexpensive oral antibiotic ciprofloxacin, which had previously been sidelined over concerns the bacterium that causes the infection was becoming resistant to it.

7 Aug 2020

Providers participating in intervention resources are more likely to follow chronic opioid therapy guidelines

Results of a new study find that providers participating in an intervention with education and resources to help manage chronic opioid therapy for patients with HIV and chronic pain are more likely to adhere to national chronic opioid therapy guidelines compared to providers who do not take part.

7 Aug 2020

Immune system derails during severe course of COVID-19

Contrary to what has been generally assumed so far, a severe course of COVID-19 does not solely result in a strong immune reaction - rather, the immune response is caught in a continuous loop of activation and inhibition.

6 Aug 2020

Humans promote diseases from the animal kingdom

The coronavirus pandemic, which has now infected nearly 19 million and killed more than 712,000 people, most likely originated from bats. Just like other coronavirus outbreaks in the past, a spill-over event or zoonosis caused the viruses to jump from animals to humans.

6 Aug 2020

Frequent HIV screenings can benefit high-risk young men who have sex with men

A new study has found that HIV screening every three months compared to annually will improve clinical outcomes and be cost-effective among high-risk young men who have sex with men (YMSM) in the United States.

6 Aug 2020

COVID-19: BCG vaccine is safe and possibly has a positive effect

The BCG vaccine, a vaccine originally made against tuberculosis, has a general stimulating effect on the immune system and is therefore effective against multiple infectious diseases - possibly also against COVID-19.

6 Aug 2020

Synthetic peptide can make multidrug-resistant bacteria sensitive to antibiotics

Scientists at Nanyang Technological University, Singapore (NTU Singapore) have developed a synthetic peptide that can make multidrug-resistant bacteria sensitive to antibiotics again when used together with traditional antibiotics, offering hope for the prospect of a combination treatment strategy to tackle certain antibiotic-tolerant infections.

6 Aug 2020

Human encroachment into forest land caused bat CoV spillover and COVID-19 emergence

A new study published on the preprint server medRxiv in August 2020 discusses the root causes underlying the emergence of such infectious diseases following their crossover of the line separating animal viruses from human. This initial event is of enormous significance.

6 Aug 2020

Carefully engineered spike protein can help develop COVID-19 vaccine

The experimental vaccine against SARS-CoV-2 that was the first to enter human trials in the United States has been shown to elicit neutralizing antibodies and a helpful T-cell response with the aid of a carefully engineered spike protein that mimics the infection-spreading part of the virus.

6 Aug 2020

New medical imaging resource center at UChicago will help tackle COVID-19 pandemic

A new center hosted at the University of Chicago -- co-led by the largest medical imaging professional organizations in the country -- will help tackle the ongoing COVID-19 pandemic by curating a massive database of medical images to help better understand and treat the disease.

5 Aug 2020

Infectious Diseases News and Research

Protein uses two different mechanisms to inhibit viral infections

Public health officials are quitting or getting fired in throes of pandemic

Finland joins international organization dedicated to COVID-19 vaccines

Specific HIV and tuberculosis medications decrease risk of death in adults with drug-resistant TB

COVID-19 Prevention Network announces Phase 3 trials to evaluate monoclonal antibodies

One-third of children hospitalized with COVID-19 admitted to ICU, study finds

Baylor Scott & White Research Institute enrolls first patients in NIH ACTIV-3 clinical trial

Mouthwashes could lower the transmission of SARS-CoV-2

Speed of Novavax vaccine development does not compromise quality of the SARS-CoV-2 immunogen

Study identifies five immune response markers that may predict COVID-19 patient outcomes

New test can pinpoint which people with gonorrhea can be cured with ciprofloxacin

Providers participating in intervention resources are more likely to follow chronic opioid therapy guidelines

Immune system derails during severe course of COVID-19

Humans promote diseases from the animal kingdom

Frequent HIV screenings can benefit high-risk young men who have sex with men

COVID-19: BCG vaccine is safe and possibly has a positive effect

Synthetic peptide can make multidrug-resistant bacteria sensitive to antibiotics

Human encroachment into forest land caused bat CoV spillover and COVID-19 emergence

Carefully engineered spike protein can help develop COVID-19 vaccine

New medical imaging resource center at UChicago will help tackle COVID-19 pandemic

Industry Focus: Infectious Diseases eBook

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

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