Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

CoronaVac elicits lower antibody response than natural SARS-CoV-2 infection, study suggests

A recent study from Thailand highlights a rather low degree of neutralization-afforded protection mounted by the inactivated whole-virus CoronaVac vaccine compared to natural infection with SARS-CoV-2 – the virus that causes COVID-19.

30 Aug 2021

Polymeric and lipid nanoparticles in self-amplifying RNA vaccines result in higher protein expression and immunogenicity

Self-amplifying RNA (saRNA) is an advanced platform for nucleic acid vaccine development. The backbone is typically derived from an alphaviral genome and encodes a gene of interest (GOI) and a viral replicase that can amplify the genomic and subgenomic RNA.

30 Aug 2021

Can molecular mimicry impact fertility in female COVID-19 patients?

There exists a possibility that COVID-19 can also affect the reproductive function in the body, which can lead to infertility in infected patients. A study published in the American Journal of Reproductive Immunology explored the impact of SARS-CoV-2 infection on reproductive functions and fertility.

30 Aug 2021

Northwestern researchers continue investigation on all aspects of COVID-19 pandemic

Northwestern Medicine scientists continue to investigate all aspects of the COVID-19 pandemic: from molecular mechanisms of infection, to child hospitalization and single-dose vaccine response.

28 Aug 2021

NIH begins clinical trial to assess extra COVID-19 vaccine dose in people with autoimmune disease

The National Institutes of Health has begun a clinical trial to assess the antibody response to an extra dose of an authorized or approved COVID-19 vaccine in people with autoimmune disease who did not respond to an original COVID-19 vaccine regimen.

27 Aug 2021

Recognizing viral genomes in quick, ‘CRISP’ ways

Researchers from China recently reviewed the latest advancements, applications, and prospects of virus detection using CRISPR-Cas systems.

27 Aug 2021

MS patients on anti-CD20 therapy have robust T cell responses to SARS-CoV-2 vaccination

Scientists have observed that MS patients exhibit a robust T cell response despite a reduced humoral response to COVID-19 vaccines. Read more here.

27 Aug 2021

ACTG announces positive data for monoclonal antibody combination therapy from the ACTIV-2 study

The AIDS Clinical Trials Group, the largest global HIV research network, which has expanded its focus to include evaluating outpatient treatment for COVID-19, today announced positive data for the monoclonal antibody combination therapy BRII-196/BRII-198 from the ACTIV-2 study of Outpatient Monoclonal Antibodies and Other Therapies.

27 Aug 2021

Cytokine APRIL plays a protective role against formation of atherosclerotic plaques

Heart attacks and strokes are the main causes of death and loss of productive years globally. These clinical complications are caused by atherosclerosis, which is a chronic disease that leads to the accumulation of LDL cholesterol and immune cells in the inner layer of arteries and thereby resulting in the build-up of atherosclerotic plaques.

26 Aug 2021

German study shows high protection from COVID-19 in over 80s with Pfizer vaccine

A new observational study in Germany, recently published on the medRxiv* preprint server, found the Comirnaty vaccine to be 68.3% effective against COVID-19 for people over 80. In those fully immunized, the vaccine was found to be 73.2% effective in preventing hospitalization and 80.1% effective against death.

26 Aug 2021

Potential variant of interest in South Africa assigned to the PANGO lineage C.1.2

Continual genomic surveillance of the SARS-CoV-2 strains in South Africa has revealed an increase in the number of sequences belonging to C.1 lineage during the third wave (May 2021) of SARS-CoV-2 infections. This observation was unexpected because C.1 was last reported in January 2021.

26 Aug 2021

Two mRNA vaccines are effective even without post-shot symptoms or prior SARS-CoV-2 infection

Vaccination with the two messenger RNA (mRNA) vaccines for SARS-CoV-2, the virus that causes COVID-19, yields a robust antibody response, even if a person did not develop significant symptoms following vaccination or did not have a prior SARS-CoV-2 infection.

26 Aug 2021

BioPlx sets out to control and combat the rise of antibiotic-resistant superbugs

Antimicrobial Resistance is "one of the greatest threats to society, human and animal health, and economic prosperity." Those are the unequivocal words regarding the gravity of antimicrobial-resistant bacteria from the National Institute of Antimicrobial Resistance Research and Education.

26 Aug 2021

Analysis of antibody titer decay following vaccination or SARS-CoV-2 infection

A new study focused on the decrease in antibody titers following two doses of BNT162b2 vaccine or SARS-CoV-2 natural infection in Israel.

25 Aug 2021

Persistence of Anti-PF4 levels in VITT patients four months after AstraZeneca COVID-19 vaccine

A study published on medRxiv* preprint server reported the over-time changes in the ability of the serum to activate platelets in vitro.

25 Aug 2021

Unconventional T cell and inflammation levels in COVID-19 during pregnancy

A new study published on the medRxiv* preprint server has focused on investigating SARS-CoV-2 immune responses in pregnant women

25 Aug 2021

Hot spots where covid vaccination lags push experimental antibody treatment

For months, Joelle Ruppert was among the millions of Americans who are covid vaccine holdouts. Her reluctance, she said, was not so much that she opposed the new vaccines but that she never felt "compelled" by the evidence supporting their experimental use.

25 Aug 2021

SARS-CoV-2 Delta likely to acquire resistance to wild-type spike vaccines

A new study published on the preprint server bioRxiv* explores the mechanism of the Delta variant's high infectivity and suggests a plausible pathway by which the Delta variant could escape from vaccine-induced immunity.

24 Aug 2021

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

The deadliest time in a viral respiratory illness sometimes is actually after the virus is cleared from the body. Destructive processes that are set in motion during an infection crest in the weeks after the virus is defeated, leading to organ damage that can cause chronic illness or even death.

24 Aug 2021

Breast milk of vaccinated mothers contains antibodies that may protect nursing infants from COVID-19

The breast milk of lactating mothers vaccinated against COVID-19 contains a significant supply of antibodies that may help protect nursing infants from the illness, according to new research from the University of Florida.

24 Aug 2021

Antibody News and Research

Further Reading

CoronaVac elicits lower antibody response than natural SARS-CoV-2 infection, study suggests

Polymeric and lipid nanoparticles in self-amplifying RNA vaccines result in higher protein expression and immunogenicity

Can molecular mimicry impact fertility in female COVID-19 patients?

Northwestern researchers continue investigation on all aspects of COVID-19 pandemic

NIH begins clinical trial to assess extra COVID-19 vaccine dose in people with autoimmune disease

Recognizing viral genomes in quick, ‘CRISP’ ways

MS patients on anti-CD20 therapy have robust T cell responses to SARS-CoV-2 vaccination

ACTG announces positive data for monoclonal antibody combination therapy from the ACTIV-2 study

Cytokine APRIL plays a protective role against formation of atherosclerotic plaques

German study shows high protection from COVID-19 in over 80s with Pfizer vaccine

Potential variant of interest in South Africa assigned to the PANGO lineage C.1.2

Two mRNA vaccines are effective even without post-shot symptoms or prior SARS-CoV-2 infection

BioPlx sets out to control and combat the rise of antibiotic-resistant superbugs

Analysis of antibody titer decay following vaccination or SARS-CoV-2 infection

Persistence of Anti-PF4 levels in VITT patients four months after AstraZeneca COVID-19 vaccine

Unconventional T cell and inflammation levels in COVID-19 during pregnancy

Hot spots where covid vaccination lags push experimental antibody treatment

SARS-CoV-2 Delta likely to acquire resistance to wild-type spike vaccines

Researchers find clues to how lung damage develops in the aftermath of a respiratory infection

Breast milk of vaccinated mothers contains antibodies that may protect nursing infants from COVID-19

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