Antibody News and Research

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An antibody is a blood protein that is produced in response to and counteracts an antigen. Antibodies are produced in response to disease and help the body fight against the particular disease. In this way, antibodies help the body develop an immunity to disease.

New clinical trial to test third dose of COVID-19 vaccine for immunocompromised people

A new clinical trial to determine whether a third dose of vaccine will improve the immune response for people who have weakened immune systems is launching in the UK.

24 Aug 2021

Study shows difference in antibody levels in response to SARS-CoV-2 infection and type of vaccination

In a recent study, researchers aimed to monitor the levels of the anti-SARS-CoV-2 spike IgG levels in populations that were subjected to routine tests.

24 Aug 2021

SARS-CoV-2 Delta variant associated with more breakthrough infections

The study highlights that compared to the previously circulating alpha variant, the delta variant is associated with higher infectious virus load and a lower level of humoral immunity in the upper respiratory tract. The study is currently available on the medRxiv* preprint server prior to peer review.

24 Aug 2021

Patients on dialysis show reduced antibody levels four months after COVID-19 vaccination

A new longitudinal study posted to the medRxiv* preprint server suggests vaccinated patients on chronic hemodialysis having waning immunity against severe acute respiratory syndrome 2 (SARS-CoV-2) variants of concern. The German researchers found a drop in neutralizing antibody levels and T cell activity four months after receiving their second Pfizer-BioNTech vaccine.

24 Aug 2021

Broad-spectrum coronavirus neutralization amongst vaccinated SARS-CoV-1 survivors

The potency of neutralizing antibodies in individuals who have recovered from SARS-CoV and received the SARS-CoV-2 vaccine is evaluated.

23 Aug 2021

Non-invasive retinal imaging may be useful for detecting Alzheimer's disease risk

Amyloid plaques are protein deposits that collect between brain cells, hindering function and eventually leading to neuronal death.

23 Aug 2021

Expansion of seasonal betacoronavirus antibodies post-vaccination is associated with reduction in neutralization of the SARS-CoV-2 variants of concern

A new study determined the antibody response to SARS-CoV-2 and seasonal viruses induced by BNT162b2-Comirnaty vaccination in healthcare workers.

23 Aug 2021

New study reveals unique immune responses to SARS-CoV-2, Ebola and respiratory syncytial virus using B cell repertoire analysis

A new study has been published on the bioRxiv* preprint server, which takes a long-read repertoire amplification approach to better understand, compare and contrast B cell responses to emerging or endemic viruses.

23 Aug 2021

Study uses computational modeling of coronavirus spike proteins to examine dynamics responsible for immunogenicity and immune escape

A new study published on the bioRxiv* preprint server focused on the development of dynamic computational models for a large subset of S proteins of SARS-CoV, MERS-CoV, and SARS-CoV-2.

23 Aug 2021

UK Health Security Agency launches antibody surveillance program for the general public

Thousands of adults a day will be given free access to antibody tests through a new national surveillance programme launched by the UK Health Security Agency next week, to help improve our understanding of immunity against COVID-19 from vaccination and infection.

23 Aug 2021

New antibody found to be highly protective against wide range of COVID-19 virus variants

The virus that causes COVID-19 today is not the same as the one that first sickened people way back in December 2019.

20 Aug 2021

A combination of oral bacteria and intranasal vaccine provide protection from influenza A virus and COVID-19

A new study published in the journal mBio focuses on the role of nasal bacteria in eliciting virus-specific adaptive immunity.

20 Aug 2021

MHRA approves first monoclonal antibody treatment for COVID-19 in the UK

Following on from a thorough review of the evidence carried out by the MHRA, and recommendation by the Commission on Human Medicines (CHM), the government's independent expert scientific advisory body, the MHRA has approved Ronapreve as the first monoclonal antibody combination product indicated for use in the prevention and treatment of acute COVID-19 infection for the UK.

20 Aug 2021

SARS-CoV-2 mutations alter dynamics of neutralizing antibodies

A new study describes how monoclonal antibodies raised against SARS-CoV-2 are affected by mutations in the antibody binding site.

20 Aug 2021

SARS-CoV-2 lambda variant escapes immune response via spike mutations

A new study explores the mechanism by which the SARS-CoV-2 lambda variant has acquired immune evasion capabilities above that of the wildtype.

20 Aug 2021

‘We sent a terrible message’: Scientists say Biden jumped the gun with vaccine booster plan

The Biden administration's plans to make covid-19 booster shots available next month has drawn a collective scream of protest from the scientific community.

20 Aug 2021

Study points to a novel strategy for developing broad-spectrum vaccines against coronaviruses

Scientists from Duke-NUS Medical School and the National Centre for Infectious Diseases (NCID) found that 2003 SARS survivors who have been vaccinated with the Pfizer-BioNTech mRNA vaccine produced highly potent functional antibodies that are capable of neutralizing not only all known SARS-CoV-2 variants of concerns (VOCs) but also other animal coronaviruses that have the potential to cause human infection.

20 Aug 2021

Antibody News and Research

Further Reading

New clinical trial to test third dose of COVID-19 vaccine for immunocompromised people

Study shows difference in antibody levels in response to SARS-CoV-2 infection and type of vaccination

SARS-CoV-2 Delta variant associated with more breakthrough infections

Patients on dialysis show reduced antibody levels four months after COVID-19 vaccination

Broad-spectrum coronavirus neutralization amongst vaccinated SARS-CoV-1 survivors

Non-invasive retinal imaging may be useful for detecting Alzheimer's disease risk

Expansion of seasonal betacoronavirus antibodies post-vaccination is associated with reduction in neutralization of the SARS-CoV-2 variants of concern

New study reveals unique immune responses to SARS-CoV-2, Ebola and respiratory syncytial virus using B cell repertoire analysis

Study uses computational modeling of coronavirus spike proteins to examine dynamics responsible for immunogenicity and immune escape

UK Health Security Agency launches antibody surveillance program for the general public

New antibody found to be highly protective against wide range of COVID-19 virus variants

A combination of oral bacteria and intranasal vaccine provide protection from influenza A virus and COVID-19

MHRA approves first monoclonal antibody treatment for COVID-19 in the UK

SARS-CoV-2 mutations alter dynamics of neutralizing antibodies

SARS-CoV-2 lambda variant escapes immune response via spike mutations

‘We sent a terrible message’: Scientists say Biden jumped the gun with vaccine booster plan

Study points to a novel strategy for developing broad-spectrum vaccines against coronaviruses

Vaccines remain the most effective way to protect against COVID-19 Delta variant, study says

Researchers identify antibodies that could protect against alphaviruses

Small study suggests a mix-and-match COVID-19 booster produces robust antibody levels

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