B Cell News and Research

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An evolutionary ancient brain region drives modern-day cognition

The superior colliculus is a midbrain region that is traditionally thought to help animals orient themselves toward important locations in space, like directing their eyes and head toward a bright flash of light. New research from the University of Chicago shows that this part of the brain also plays a role in complex cognitive tasks like visual categorization and decision making.

19 Sep 2024

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Researchers have discovered that remodeling of extracellular matrix (ECM) in the hypothalamus, specifically around AgRP neurons, drives insulin resistance and metabolic disease. Disrupting this ECM buildup improves insulin sensitivity and may be a promising treatment for obesity and diabetes.

19 Sep 2024

Do long genes hold the key to understanding the genetic underpinnings of aging?

Review highlights the growing evidence that aging is linked to reduced expression of long genes, offering insights into potential anti-aging therapies based on gene length.

19 Sep 2024

Study reveals MYC gene's role in prostate cancer initiation and progression

By tracking the changes in prostate cancer cells over time, researchers at the Johns Hopkins Kimmel Cancer Center have found that activation of the MYC gene - a well-known cancer-causing gene - sets off a cascade of events that leads to both initiation and progression of the disease.

19 Sep 2024

Study reveals biomarkers that predict disability worsening in multiple sclerosis

A pioneering study presented today at ECTRIMS 2024 has identified critical biomarkers that can predict disability worsening in multiple sclerosis (MS).

19 Sep 2024

FORT-2 trial shows promising results for bladder cancer immunotherapy combination

Findings from the international FORT-2 clinical trial showed that a combination treatment including immunotherapy is safe and tolerable in patients with locally advanced or metastatic bladder cancer.

19 Sep 2024

Study reveals impact of human breast milk on infant microbiome and respiratory health

Human breast milk regulates a baby's mix of microbes, or microbiome, during the infant's first year of life. This in turn lowers the child's risk of developing asthma, a new study shows.

19 Sep 2024

Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma

A team of researchers from City of Hope®, one of the largest and most advanced cancer research and treatment organizations in the U.S., and The University of Texas M.D. Anderson Cancer Center, have reported safety and efficacy results from a Phase 1 trial that featured a personalized vaccine to treat lymphoplasmacytic lymphoma, a rare and slow-growing type of blood cancer, according to a study published recently in Nature Communications.

19 Sep 2024

New method identifies biomarkers in wastewater using origami-paper sensors

Researchers at Cranfield University have developed an innovative new method for identifying biomarkers in wastewater using origami-paper sensors, enabling the tracking of infectious diseases using the camera in a mobile phone.

19 Sep 2024

New model reveals mechanisms of lung injury from mechanical ventilation

For the first time, scientists are able to directly compare the different kinds of injury that mechanical ventilation causes to cells in the lungs.

19 Sep 2024

Hypoxia's hidden role in boosting anti-cancer immunity

In the complex landscape of cancer, tumors create their own microenvironment, often marked by low oxygen levels, a condition known as hypoxia.

19 Sep 2024

Chan Zuckerberg initiative joins Scale Bio's ‘100 Million Cell Challenge’ to accelerate single cell genomics research

The '100 Million Cell Challenge' invites proposals for large-scale single cell studies, with CZI funding 50 million cells to accelerate scientific discoveries.

19 Sep 2024

Rice and Baylor receive $2.8 million to suppress inflammation and lung damage in ARDS patients

Rice University and Baylor College of Medicine have received $2.8 million in funding from the National Heart, Lung, and Blood Institute (NHLBI), a division of the National Institutes of Health (NIH), for research on reducing inflammation and lung damage in acute respiratory distress syndrome (ARDS) patients.

19 Sep 2024

Study highlights the importance of placental evaluation in pregnancy outcomes

In an opinion article publishing September 18 in the Cell Press journal Trends in Molecular Medicine, physician-scientists argue that with most placentas discarded after birth, placental pathology is underutilized clinically, should be a routine part of obstetric and neonatal care, and also deserves more research attention.

19 Sep 2024

New kidney chip offers breakthrough for drug development and personalized medicine

Developing advanced drug screening tools is crucial for the advancement of personalized medicine and the creation of more effective treatments. One organ receiving particular attention in this area is the kidney.

19 Sep 2024

Researchers uncover receptor that dampens sensory input

Signals in our brain are not always processed in the same way: Certain receptors modulate these mechanisms, influencing our mood, perception, and behavior in various ways. One of these is the 5-HT2A receptor, which has a recently discovered unique characteristic.

18 Sep 2024

Asimov launches AAV Edge, a suite of AI models, host cells, and genetic tools for end-to-end gene therapy development

Asimov, the synthetic biology company advancing the design and production of therapeutics, today announced the launch of the AAV Edge System, a comprehensive suite of tools for adeno-associated viral (AAV) gene therapy design and manufacturing.

18 Sep 2024

Scientists investigate the rise in early-onset cancers and propose new strategies to combat growing epidemic

Researchers explore the global rise in early-onset cancers, linking environmental exposures and lifestyle changes to the surge, and advocate for tailored prevention and treatment strategies.

18 Sep 2024

Leptin variations may influence brain health and dementia development

New research is more closely linking obesity to dementia. Higher levels of leptin, a hormone that helps maintain normal body weight, is associated with better signal-transmitting brain white matter in middle-aged adults, according to a study by The University of Texas Health Science Center at San Antonio (UT Health San Antonio).

18 Sep 2024

Direct breastfeeding boosts microbial transfer to very-low-birth-weight infant guts

Researchers found that 30-40% of the very-low-birth-weight infant's gut microbiota came from the mother’s milk, and direct breastfeeding enhances microbial transmission despite antibiotic exposure.

18 Sep 2024

B Cell News and Research

An evolutionary ancient brain region drives modern-day cognition

Hypothalamic ECM remodeling drives insulin resistance, contributing to obesity and diabetes

Do long genes hold the key to understanding the genetic underpinnings of aging?

Study reveals MYC gene's role in prostate cancer initiation and progression

Study reveals biomarkers that predict disability worsening in multiple sclerosis

FORT-2 trial shows promising results for bladder cancer immunotherapy combination

Study reveals impact of human breast milk on infant microbiome and respiratory health

Phase 1 trial shows safety and efficacy of personalized vaccine for lymphoplasmacytic lymphoma

New method identifies biomarkers in wastewater using origami-paper sensors

New model reveals mechanisms of lung injury from mechanical ventilation

Hypoxia's hidden role in boosting anti-cancer immunity

Chan Zuckerberg initiative joins Scale Bio's ‘100 Million Cell Challenge’ to accelerate single cell genomics research

Rice and Baylor receive $2.8 million to suppress inflammation and lung damage in ARDS patients

Study highlights the importance of placental evaluation in pregnancy outcomes

New kidney chip offers breakthrough for drug development and personalized medicine

Researchers uncover receptor that dampens sensory input

Asimov launches AAV Edge, a suite of AI models, host cells, and genetic tools for end-to-end gene therapy development

Scientists investigate the rise in early-onset cancers and propose new strategies to combat growing epidemic

Leptin variations may influence brain health and dementia development

Direct breastfeeding boosts microbial transfer to very-low-birth-weight infant guts

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