Gene Editing News and Research

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Researchers repurpose gene-editing tool CRISPR to develop better antibiotics

A University of Wisconsin-Madison researcher and his collaborators at the University of California, San Francisco have repurposed the gene-editing tool CRISPR to study which genes are targeted by particular antibiotics, providing clues on how to improve existing antibiotics or develop new ones.

11 Jan 2019

Defective astrocytes linked to alpha-synuclein accumulation in Parkinson's

Researchers have found that defects in brain glial cells called astrocytes are linked to the accumulation of alpha-synuclein in Parkinson's disease.

10 Jan 2019

NYSCF announce partnership with Ngene to develop new disease treatments

The New York Stem Cell Foundation Research Institute today announced a partnership with Ngene Therapeutics Inc. to develop new disease treatments that leverage human stem cell research and novel gene editing techniques.

10 Jan 2019

Researchers identify and overcome barrier in CRISPR gene editing to treat muscular dystrophy

The gene editing technique known as CRISPR is a revolutionary approach to treating inherited diseases. However, the tool has yet to be used to effectively treat long-term, chronic conditions.

9 Jan 2019

Researchers develop CRISPR-based method to control pests with precision-guided genetics

Using the CRISPR gene editing tool, Nikolay Kandul, Omar Akbari and their colleagues at UC San Diego and UC Berkeley devised a method of altering key genes that control insect sex determination and fertility.

8 Jan 2019

Active ingredient in eye drops shows promise for treating aggressive blood cancer

An active ingredient in eye drops that were being developed for the treatment of a form of eye disease has shown promise for treating an aggressive form of blood cancer. Scientists at the Wellcome Sanger Institute, University of Cambridge, University of Nottingham and their collaborators have found that this compound, which targets an essential cancer gene, could kill leukemia cells without harming non-leukemic blood cells.

19 Dec 2018

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

Horizon Discovery Group today announces that it has entered into an exclusive target discovery partnership with C4XD, a pioneering drug discovery company.

From Revvity 19 Dec 2018

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

The CRISPR-Cas9 gene editing system may be able to restore the effectiveness of first-line chemotherapies used to treat lung cancer by deleting or "knocking out" a gene in cancer tumors that helps the tumors develop resistance to the drugs.

18 Dec 2018

Neuroscience-protein that creates borders inside the brain

Boundaries between different regions of the brain are essential for the brain to function. Research to-date has shown that molecular machineries located at the cell membrane such as cell adhesion molecules are responsible for regulating the boundary formation.

18 Dec 2018

Mechanisms behind neonatal diabetes uncovered

Researchers at the University of Helsinki, Finland, have described mechanisms linking chronic cellular stress to the poor development of the insulin-producing cells.

17 Dec 2018

Genetically modified pigs could limit replication of classical swine fever virus, study shows

Researchers have developed genetically modified pigs that are protected from classical swine fever virus, according to a study published December 13 in the open-access journal PLOS Pathogens by Hongsheng Ouyang of Jilin University, and colleagues.

14 Dec 2018

Scientists discover rules that determine precision of CRISPR/Cas9 genome editing in human cells

Scientists at the Francis Crick Institute have discovered a set of simple rules that determine the precision of CRISPR/Cas9 genome editing in human cells.

14 Dec 2018

New research lays out potential path for treatment of Huntington’s disease

New research gives scientists a clearer picture of what is happening in the brains of people with Huntington's disease and lays out a potential path for treatment.

14 Dec 2018

Study uncovers new genetic clues to frontotemporal dementia

Unlike the more common Alzheimer's disease, frontotemporal dementia tends to afflict young people. It accounts for an estimated 20 percent of all cases of early-onset dementia.

13 Dec 2018

New discovery will improve the safety and predictability of CRISPR

Scientists have discovered a simple set of rules that can be used to precisely predict how DNA will be modified by the CRISPR gene editing technique.

13 Dec 2018

Scientists develop new stem cell line to study conversion of stem cells into muscle

To help patients with muscle disorders, scientists at The University of Texas Health Science Center at Houston (UTHealth) have engineered a new stem cell line to study the conversion of stem cells into muscle. Findings appeared in Cell Reports.

13 Dec 2018

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

A Massachusetts General Hospital research team has created a new mouse model of a common form of muscular dystrophy with the potential of rapidly distinguishing promising therapeutic drugs from those unlikely to be successful.

13 Dec 2018

Cancer Research UK and AstraZeneca open new Functional Genomics Centre

Cancer Research UK and AstraZeneca have announced today (Monday) that they are opening a new center in the UK, dedicated to realizing the full potential of functional genomics in the discovery and development of new drugs for patients with cancer.

10 Dec 2018

Researchers create new light-activated tools for controlling neurons

By enabling super-fast remote control of specific cells, light-activated proteins allow researchers to study the function of individual neurons within a large network - even an entire brain. Now one of the pioneers of 'optogenetics' and colleagues have created two new tools - protein pores which when illuminated allow Ca2+ into cells or K+ out - for switching neurons on or off using light.

6 Dec 2018

Xenotransplantation - Pig heart transplants keep baboons alive

A group of researchers have successfully transplanted pig hearts onto baboons and studied then for a long duration to see if the transplant was a success.

5 Dec 2018

Gene Editing News and Research

Researchers repurpose gene-editing tool CRISPR to develop better antibiotics

Defective astrocytes linked to alpha-synuclein accumulation in Parkinson's

NYSCF announce partnership with Ngene to develop new disease treatments

Researchers identify and overcome barrier in CRISPR gene editing to treat muscular dystrophy

Researchers develop CRISPR-based method to control pests with precision-guided genetics

Active ingredient in eye drops shows promise for treating aggressive blood cancer

Horizon Discovery partners with C4XD to validate novel synthetic lethal oncology targets

CRISPR may restore effectiveness of chemotherapies used to treat lung cancer

Neuroscience-protein that creates borders inside the brain

Mechanisms behind neonatal diabetes uncovered

Genetically modified pigs could limit replication of classical swine fever virus, study shows

Scientists discover rules that determine precision of CRISPR/Cas9 genome editing in human cells

New research lays out potential path for treatment of Huntington’s disease

Study uncovers new genetic clues to frontotemporal dementia

New discovery will improve the safety and predictability of CRISPR

Scientists develop new stem cell line to study conversion of stem cells into muscle

New mouse model shows potential for rapid identification of promising muscular dystrophy therapies

Cancer Research UK and AstraZeneca open new Functional Genomics Centre

Researchers create new light-activated tools for controlling neurons

Xenotransplantation - Pig heart transplants keep baboons alive

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Expanding research and clinical options for children with cancer

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