Heart Failure News and Research

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Heart failure (HF) is a condition in which a problem with the structure or function of the heart impairs its ability to supply sufficient blood flow to meet the body's needs. It should not be confused with cardiac arrest or myocardial infarction.

New system uses ECG and blood markers for Takotsubo Syndrome

It's often mistaken for a heart attack, but Takotsubo cardiomyopathy – previously known as Broken Heart syndrome – is a serious and sometimes fatal heart condition increasingly reported in intensive care units (ICUs). Yet without a clear clinical pathway in ICUs, it's often missed, putting critically ill patients at risk.

19 Aug 2025

Early puberty and childbirth tied to accelerated aging and higher disease risk

Reproductive timing matters when it comes to aging and age-related disease. In a study now online at eLife¸ Buck researchers determine that girls who go through puberty (the onset of menstruation) before the age of 11 or women who give birth before the age of 21 have double the risk of developing type 2 diabetes, heart failure and obesity and quadruple the risk of developing severe metabolic disorders.

18 Aug 2025

Community pop-up screenings uncover hidden cardiovascular risk factors

Pop-up screening for atherosclerotic cardiovascular disease (ASCVD) risk held at community pharmacies and large-scale sporting events can identify people with uncontrolled cardiovascular risk factors, according to a study published in JACC, the flagship journal of the American College of Cardiology, and simultaneously presented at the 73rd Annual Scientific Meeting of the Cardiac Society of Australia and New Zealand.

17 Aug 2025

Trial finds no cardiovascular benefit and higher safety risks with spironolactone in dialysis patients

A large international study has found that spironolactone, a medication for high blood pressure and heart failure, does not reduce the risk of heart-related death or hospitalizations in people with kidney failure receiving dialysis, despite earlier smaller studies suggesting benefit.

17 Aug 2025

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Preventing and managing high blood pressure with healthy lifestyle behaviors, such as following a heart-healthy diet including reducing salt intake, staying physically active, maintaining a healthy weight and managing stress—combined with early treatment with medication to lower blood pressure if necessary—are recommended to reduce the risk of heart attack, stroke, heart failure, kidney disease, cognitive decline and dementia, according to a new clinical guideline published today in the American Heart Association's peer-reviewed journals Circulation and Hypertension, and in JACC, the flagship journal of the American College of Cardiology.

14 Aug 2025

Pregabalin raises heart failure risk in older adults compared to gabapentin, study finds

A large Medicare cohort study found that older adults prescribed pregabalin had a significantly higher risk of developing heart failure compared to those prescribed gabapentin. The elevated risk was most pronounced in individuals with pre-existing cardiovascular disease, especially women and White patients.

13 Aug 2025

New research highlights combined impact of genes and lifestyle on dilated cardiomyopathy

An international team, led by scientists from the Victor Chang Cardiac Research Institute has studied around 3000 people affected by the heart disease dilated cardiomyopathy (DCM) – a driver of heart failure and sudden cardiac arrest.

12 Aug 2025

Study identifies risk factors that increase risk of death in children with Fontan circulatory failure

A multi-center study has identified critical risk factors that increase the likelihood of death in children with a heart defect who are awaiting or have recently undergone heart transplantation, according to findings published in Circulation.

11 Aug 2025

New Canadian guideline highlights expanded role of obesity medications

"Pharmacotherapy can help people living with obesity improve overall health, not just lose weight," says Dr. Sue D. Pedersen, MD, endocrinologist and obesity medicine specialist in Calgary, and lead author of this guideline. "The goal of obesity medications is to improve metabolic, mechanical, and/or mental health, and improve quality of life, incorporating treatment goals that are important to each individual patient."

11 Aug 2025

Fetal procedure dramatically reduces mortality in high-risk Vein of Galen Malformation cases

Building upon the success of the first in utero brain surgery for Vein of Galen Malformation (VOGM) reported in 2023, new data published today in JAMA provides further evidence for the potential use of fetal embolization for this condition.

11 Aug 2025

Vital role of physical activity in early type 2 diabetes care

New research to be presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD) in Vienna, Austria (15-19 September) shows, among people recently diagnosed with type with type 2 diabetes and no previous cardiovascular disease, a clear association exists between a person's self-reported physical activity and their risk of all-cause mortality and major adverse cardiac events (MACE), that include heart attacks and strokes.

8 Aug 2025

Faster and further walking lowers heart disease and stroke risks

Analysis of over 36,000 people with high blood pressure has shown that taking more steps, even below the recommended daily target of 10,000 steps, and walking faster, is associated with a significant reduction in the risk of major problems of the heart and blood vessels.

6 Aug 2025

Air purifiers can lower blood pressure in at-risk adults

Using portable high-efficiency particulate air (HEPA) purifiers at home can significantly lower systolic blood pressure (SBP) in adults with elevated baseline readings — even in areas with relatively low overall air pollution levels, according to a study published today in JACC, the flagship journal of the American College of Cardiology.

6 Aug 2025

Alzheimer’s risk factors look different for men and women

Research on Alzheimer's risk factors shows significant sex differences, with implications for diagnosis and treatment in early-onset and late-onset cases.

6 Aug 2025

TEER shows promising outcomes in elderly patients with atrial functional mitral regurgitation

The mitral valve controls blood flow between the heart's left atrium and ventricle. When structural changes affect the atrium or valve, it may not close fully-causing blood to leak backwards, a condition known as atrial functional mitral regurgitation (AFMR).

6 Aug 2025

Researchers uncover PSAT1 gene as key to heart repair post-heart attack

Heart attacks remain a leading cause of death and disability worldwide. The permanent loss of heart muscle cells-known as cardiomyocytes-and the heart's limited regenerative capacity often led to chronic heart failure.

1 Aug 2025

Brisk walking for just 15 minutes a day cuts death risk in low-income adults, study shows

Fast walking for as little as 15 minutes per day was linked to a nearly 20% reduction in mortality among predominantly Black and low-income American adults. Slow walking showed minimal benefit, but prolonged slow walking reduced the risk of death from ischemic heart disease.

30 Jul 2025

Most US adults have older heart age than actual age

Most U.S. adults have a "heart age" several years older than their chronological age - sometimes by more than a decade.

30 Jul 2025

Exercise-based cardiac rehab benefits atrial fibrillation

Exercise-based cardiac rehabilitation lessens the severity, frequency, and recurrence of the most common form of irregular heart rhythm, atrial fibrillation, or AF for short, finds a pooled data analysis of the available research, published online in the British Journal of Sports Medicine.

30 Jul 2025

How a leaky gut could be putting your heart at risk

Researchers reviewed recent studies showing that gut dysbiosis contributes to heart failure by weakening the gut barrier, enabling harmful metabolites like TMAO to trigger inflammation and cardiac damage. The review highlights a bidirectional “gut-heart axis” and points to new avenues for dietary and microbial therapies.

28 Jul 2025

Heart Failure News and Research

Further Reading

New system uses ECG and blood markers for Takotsubo Syndrome

Early puberty and childbirth tied to accelerated aging and higher disease risk

Community pop-up screenings uncover hidden cardiovascular risk factors

Trial finds no cardiovascular benefit and higher safety risks with spironolactone in dialysis patients

New 2025 guidelines focus on early intervention and lifestyle to manage high blood pressure

Pregabalin raises heart failure risk in older adults compared to gabapentin, study finds

New research highlights combined impact of genes and lifestyle on dilated cardiomyopathy

Study identifies risk factors that increase risk of death in children with Fontan circulatory failure

New Canadian guideline highlights expanded role of obesity medications

Fetal procedure dramatically reduces mortality in high-risk Vein of Galen Malformation cases

Vital role of physical activity in early type 2 diabetes care

Faster and further walking lowers heart disease and stroke risks

Air purifiers can lower blood pressure in at-risk adults

Alzheimer’s risk factors look different for men and women

TEER shows promising outcomes in elderly patients with atrial functional mitral regurgitation

Researchers uncover PSAT1 gene as key to heart repair post-heart attack

Brisk walking for just 15 minutes a day cuts death risk in low-income adults, study shows

Most US adults have older heart age than actual age

Exercise-based cardiac rehab benefits atrial fibrillation

How a leaky gut could be putting your heart at risk

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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