Lipids News and Research

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Lipids are a broad group of naturally-occurring molecules which includes fats, waxes, sterols, fat-soluble vitamins (such as vitamins A, D, E and K), monoglycerides, diglycerides, phospholipids, and others. The main biological functions of lipids include energy storage, as structural components of cell membranes, and as important signaling molecules.

Tea, apples, and chocolate proven to support liver health

A flavonoid-rich diet, including apples, tea, and dark chocolate, significantly lowers the risk of non-alcoholic fatty liver disease (NAFLD) and improves liver health biomarkers. These findings highlight the potential of dietary flavonoids in combating liver fat accumulation and inflammation.

9 Dec 2024

Researchers identify key mechanisms behind heart disease in type 2 diabetes

People with type 2 diabetes have a higher risk of developing cardiovascular disease and dying prematurely due to atherosclerosis.

9 Dec 2024

New insights into the mechanisms of "Niemann-Pick type C" in children

In the journal "Science Translational Medicine", scientists from DZNE and LMU Hospital report on new insights into the mechanisms of "Niemann-Pick type C" (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood.

6 Dec 2024

Liver conversion of fructose fuels cancer growth by supplying lipids for tumor proliferation

This research highlights the indirect role of fructose in cancer, revealing how liver metabolism enhances tumor growth through lipid-mediated mechanisms.

5 Dec 2024

Fructose consumption linked to accelerated tumor growth in cancer models

Fructose consumption has increased considerably over the past five decades, largely due to the widespread use of high-fructose corn syrup as a sweetener in beverages and ultra-processed foods.

4 Dec 2024

Higher plant-based protein intake linked to lower heart disease risk

Eating a diet with a higher ratio of plant-based protein to animal-based protein may reduce the risk of cardiovascular disease (CVD) and coronary heart disease (CHD), according to a new study led by researchers at Harvard T.H. Chan School of Public Health.

2 Dec 2024

Can beef fit in a heart-healthy diet? Review provides new insights

A systematic review suggests unprocessed beef has minimal impact on cardiovascular health markers.

1 Dec 2024

Research sheds light on how fat cells safely enlarge to store energy

A team at the Centro Nacional de Investigaciones Cardiovasculares (CNIC), led by Professor Miguel Ángel del Pozo Barriuso, who heads the Mechanoadaptation and Caveolae Biology group at the CNIC, has identified an essential mechanism in fat cells (adipocytes) that enables them to enlarge safely to store energy.

28 Nov 2024

Atlas maps plasma proteins to transform disease diagnosis and treatment

Researchers have developed the most comprehensive atlas linking plasma proteins to diseases and traits in over 53,000 individuals, offering groundbreaking insights for precision medicine. This resource uncovers 168,100 protein-disease associations and identifies new therapeutic targets.

25 Nov 2024

Pioneering protocol sheds light on NMDA receptor distribution in Alzheimer's brains

Researchers from the Institute for Neurosciences (IN), a joint center of the Miguel Hernández University of Elche (UMH) and the Spanish National Research Council (CSIC), who are also part of the Network Center for Biomedical Research in Neurodegenerative Diseases (CIBERNED) and the Alicante Institute for Health and Biomedical Research (ISABIAL), have developed a cellular fractionation protocol.

22 Nov 2024

Penn engineers cook up a new way for safer, more effective mRNA therapies

Penn Engineers have cooked up a new way to improve mRNA delivery, developing an optimal "recipe" for ionizable lipids - key ingredients in lipid nanoparticles (LNPs), the molecules behind the COVID-19 vaccines and other innovative therapies.

22 Nov 2024

Decoding the genetic roots of stroke and heart attack

In a new study published in the European Heart Journal, researchers at Karolinska Institutet show that genetic traits influence the cellular composition of atherosclerotic plaques, which over time will affect the risk of such lesions to cause a stroke or heart attack. The new knowledge can be used to improve the risk assessment and treatment of patients with atherosclerosis in the future.

20 Nov 2024

Barcoding small extracellular vesicles with new CRISPR-based system

Cell-to-cell communication through nanosized particles, working as messengers and carriers, can now be analyzed in a whole new way, thanks to a new method involving CRISPR gene-editing technology.

20 Nov 2024

New research links sphingolipids to heart disease and atherosclerosis

Excess cholesterol is known to form artery-clogging plaques that can lead to stroke, arterial disease, heart attack, and more, making it the focus of many heart health campaigns.

19 Nov 2024

Researchers make progress toward inhalable mRNA medicines

Most people don't enjoy getting shots for treatments or vaccines. So, researchers are working to create more medicines, such as those made from messenger RNA (mRNA), that can be sprayed and inhaled.

14 Nov 2024

Primary care clinicians key to achieving optimal cardiovascular health

Primary care clinicians and practices are uniquely positioned to help people achieve optimal cardiovascular health through screening, diagnosing and treating the health behaviors and factors outlined in the American Heart Association's Life's Essential 8 health metrics to reduce the risk for heart disease and stroke, according to a new scientific statement published today in the Association's peer-reviewed journal Circulation: Cardiovascular Quality and Outcomes.

13 Nov 2024

UAB researchers reverse liver disease in mice with gene therapy

UAB researchers have reversed metabolic dysfunction-associated steatohepatitis (MASH) in mouse models. MASH is a severe liver disease associated with obesity and type 2 diabetes that affects more than 40 million people.

13 Nov 2024

Study provides new insights into the central role of goblet cells

In a recent study, researchers at the University of California, San Diego, have provided new insights into the central role of goblet cells - specialized cells that line the gut - in maintaining a healthy and balanced immune environment within the gastrointestinal (GI) tract.

12 Nov 2024

Adipo Therapeutics shares results of studies on potential obesity treatment

Adipo Therapeutics LLC, a late-stage, preclinical biopharmaceutical company developing a potential treatment for obesity and related metabolic disorders, presented data from two studies at the annual meeting of The Obesity Society in San Antonio.

7 Nov 2024

UCD leads major EU project on extracellular vesicles for biomedical research

A major EU project coordinated from UCD is set to push the frontiers of biomedical research by exploring the transformative potential of extracellular vesicles (EVs).

7 Nov 2024