Sedative News and Research

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A sedative is a substance that induces sedation by reducing irritability or excitement.

New sleep medication Ramelteon shows less potential to foster abuse and dependence

As part of the effort to develop effective behavioral and medical sleep therapies, scientists consider the potential for dependence and abuse associated with prescription sleep drugs.

27 Jun 2006

FDA approves Prezista (darunavir)

FDA approves Prezista (darunavir), a new drug for adults whose infection with the human immunodeficiency virus (HIV) has not responded to treatment with other antiretroviral drugs.

26 Jun 2006

New drug will treat those winter blues

The U.S. Food and Drug Administration (FDA) has given it's approval for a drug to treat a condition known as Seasonal Affective Disorder (SAD).

14 Jun 2006

What is it about grapefruit juice that affects some drugs?

Researchers in the United States say they have identified the compound in grapefruit juice that affects how some drugs are absorbed in the body and produces unwanted side effects.

14 May 2006

Improving care for Alzheimer disease sufferers

Behavioral and psychological symptoms of dementia represent a major challenge in the care of older adults with Alzheimer disease.

12 May 2006

Alcohol use, comorbidity, and mortality

Older men who drink as few as two drinks twice a week and also have diseases that could be worsened by alcohol or cause problems with medications taken while drinking alcohol have higher death rates, as compared to men who either drink less or may drink more but don't have such comorbidities.

11 Apr 2006

Shape and function of the heart improves with apnea treatment

Patients with obstructive sleep apnea have enlarged and thickened hearts that pump less effectively, but the heart abnormalities improve with use of a device that helps patients breathe better during sleep, according to a new study in the April 4, 2006, issue of the Journal of the American College of Cardiology.

4 Apr 2006

Strange behaviour blamed on sleeping pills

Reports of some very strange behavior by insomniacs taking a prescribed sleeping pill have been of concern and have raised safety questions about insomnia medications.

16 Mar 2006

Low pressure and low oxygen factors in DVT and long flights

Researchers say that the risk of deep vein thrombosis (DVT) during flights may not be due simply to sitting still; they say the low pressure and low oxygen environment during air travel may also contribute to the development of deep vein thrombosis in some susceptible individuals.

13 Mar 2006

Women more vulnerable to effects of alcohol use

Although women consume less alcohol than men, they are more susceptible to some of the negative medical consequences of alcohol use, such as cirrhosis of the liver, cardiac disease, and cognitive impairments.

6 Jan 2006

For older people, the risks outweigh the benefits of taking sleeping pills and other sedatives

Insomnia can often affect the quality of life for older people and between 5% and 33% of older people in the UK are prescribed sleeping pills such as benzodiazepine.

14 Nov 2005

Fruits and vegetables can increase or decrease the activity and toxicity of orally-administered drugs

Eating fruits and vegetables is essential to living a long and healthy life, yet research has shown they can cause dangerous interactions with medicines.

5 Oct 2005

First trial of pramipexole for the treatment of fibromyalgia

The mechanism of fibromyalgia, a chronic illness characterized by muscle pain, fatigue, and sleep disturbances, is unknown and medications used to treat it (such as antidepressants, antiepileptics, muscle relaxants, antiinflammatories, sedative hypnotics, pain relievers and nutriceuticals) have had limited success.

28 Jul 2005

Opiates themselves are superior to sedatives for treating infants born to women who used heroin or methadone while pregnant

Opiates appear to better "ameliorate the withdrawal, facilitate feeding and potentially reduce the likelihood of seizures," according to two new systematic reviews done by David Osborn, a neonatologist at the Royal Prince Alfred Hospital in Sydney, Australia, and colleagues.

26 Jul 2005

Exercise and back support improves balance in elderly

By wearing a unique weighted back support device and participating in a special exercise program, women over 60 with osteoporosis-caused curvature of the spine improved their balance and experienced diminished back pain, giving researchers at Mayo Clinic a promising therapy to reduce falls among this population.

6 Jul 2005

The most frequently used drugs for treating chronic insomnia have never been approved for that purpose

Vaughn McCall, M.D., M.S., professor and chairman of the Department of Psychiatry and Behavioral Medicine, told a special consensus panel at the National Institutes of Health (NIH) that he could find no evidence that randomized controlled clinical trials had ever been conducted for five of the 10 pharmaceuticals prescribed most often for chronic insomnia.

14 Jun 2005

Listening to favorite music during surgery lessens need for sedative

Patients listening to their favorite music required much less sedation during surgery than did patients who listened to white noise or operating room noise, according to a Yale School of Medicine study published in May.

26 May 2005

Valium puts humans and amoeba to sleep

Biologists at University of California, San Diego (UCSD) have discovered that the popular sedative Valium has similar effects on the social amoeba Dictyostelium discoideum as it does in humans. Their surprising finding that Valium, as well as a "natural Valium" molecule found in human brains, causes the social amoeba to enter a dormant or "sleep" phase, may provide new insights into how cells in higher organisms, including humans, communicate with each other.

16 May 2005

Soft music at bedtime will help older adults sleep better and longer

Sleep, a vital ingredient in life, can sometimes become difficult as humans get older. But a recent study by researchers at Case Western Reserve University's Frances Payne Bolton School of Nursing and the Buddhist Tzu-Chi General Hospital in Taiwan shows that listening to soft music at bedtime will help older adults sleep better and longer.

6 Apr 2005

Contrary to common wisdom, sleeping pills may not increase fall risk

In nursing homes across the country, elderly people with insomnia often go untreated, because of the perception that sleeping pills increase the risk of falls and injuries that are a bane of old age.

6 Apr 2005