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Rockefeller scientists shed new light on the neuroscience of sleep

A good night of sleep entails about eight hours of blissful immobility--a state of near paralysis that, though welcome at night, would be inconvenient during the day. In a recent paper published in Cell Reports, Rockefeller scientists shed new light on the transitions between a wakeful, active state and the stillness of sleep.

1 Jun 2018

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

A decay of brain function is a hallmark of Parkinson's disease and dementia with Lewy bodies, or DLB. Specifically, cognitive dysfunction defines DLB, and nearly eight of every 10 Parkinson's patients develop dementia.

11 May 2018

New research sheds light on how neurons in the brain communicate with one another

Researchers from the University of Leicester have shed new light on how neurons in the brain communicate with one another. This could potentially help in our understanding of how and why a range of neurodegenerative diseases occur.

10 Apr 2018

Validating the Diagnosis of Depression

It’s very difficult to diagnose depression. With depression, you can't open the brain to find answers, and the chemistry of the brain is separate from the chemistry of the body.

From Pittcon 10 Apr 2018

New brain cells are added in elderly adult brains too

Scientists have long debated the fact that brains change with age and no new brain cells or neurons are added once an adult is fully grown. With age the number of neurons begins to decline leading to several problems with memory and cognition.

6 Apr 2018

New study identifies key role for particular gene in 16p11.2 deletion syndrome

In a new study of one of the most common genetic causes of autism, neuroscientists at MIT's Picower Institute for Learning and Memory have identified a specific molecular mechanism that appears to undermine the ability of neurons in affected mice to properly incorporate changes driven by experience.

20 Mar 2018

Study reveals mechanisms underlying maintenance of memory during sleep hours

During the hours of sleep the memory performs a cleaning shift. A study led by a Spanish scientist at the University of Cambridge reveals that when we sleep, the neural connections that collect important information are strengthened and those created from irrelevant data are weakened until they get lost.

15 Mar 2018

OIST scientists model molecular basis of learning in the cerebellum

The process we call learning is in fact a well-orchestrated symphony of thousands of molecular reactions, but the exact interplay between these reactions remains largely unknown.

15 Mar 2018

Study highlights divergent molecular mechanisms contributing to depression in men and women

Men and women with major depressive disorder have opposite changes in the expression of the same genes, according to a new postmortem brain study by researchers at the University of Pittsburgh and Centre for Addiction and Mental Health, Toronto, Canada.

14 Mar 2018

Treatments targeted to enhance brain neurotrophic factor signaling may improve memory functions

Treatments targeted to enhance brain neurotrophic factor signaling could improve memory functions in Alzheimer's disease even though they don't alter brain amyloid burden, according to recent research from the University of Eastern Finland.

6 Mar 2018

Receptors crucial for establishing strong memories

When we create a memory, a pattern of connections forms between neurons in the brain. New work from UC Davis shows how these connections can be strengthened or weakened at a molecular level. The study is published Feb. 27 in the journal Cell Reports.

27 Feb 2018

Researchers successfully graft human neural stem cells into monkeys with spinal cord injuries

Led by researchers at University of California San Diego School of Medicine, a diverse team of neuroscientists and surgeons successfully grafted human neural progenitor cells into rhesus monkeys with spinal cord injuries.

27 Feb 2018

Researchers demonstrate novel process to produce cell-sized lipid vesicles

A team of researchers at the University of California in Irvine, California has demonstrated a novel process to produce cell-sized lipid vesicles (CLVs) from microfluidically generated double emulsion templates by investigating the interfacial parameters that control double emulsion stability for storage, and their subsequent dewetting to form multisomes or GUVs (subsets of CLVs).

24 Feb 2018

Study finds novel therapeutic strategy that preserves neuromuscular synapses in ALS mouse model

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig's disease, causes lethal respiratory paralysis within several years of diagnosis. There are no effective treatments to slow or halt this devastating disease.

21 Feb 2018

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Increasing evidence has linked autism spectrum disorder with dysfunction of the brain's cerebellum, but the details have been unclear. In a new study, researchers at Boston Children's Hospital used stem cell technology to create cerebellar cells known as Purkinje cells from patients with tuberous sclerosis complex, a genetic syndrome that often includes ASD-like features.

19 Feb 2018

Synapse News and Research

Rockefeller scientists shed new light on the neuroscience of sleep

UAB researchers unravel brain neuron dysfunction in Parkinson’s disease and dementia with Lewy bodies

New research sheds light on how neurons in the brain communicate with one another

Validating the Diagnosis of Depression

New brain cells are added in elderly adult brains too

New study identifies key role for particular gene in 16p11.2 deletion syndrome

Study reveals mechanisms underlying maintenance of memory during sleep hours

OIST scientists model molecular basis of learning in the cerebellum

Study highlights divergent molecular mechanisms contributing to depression in men and women

Treatments targeted to enhance brain neurotrophic factor signaling may improve memory functions

Receptors crucial for establishing strong memories

Researchers successfully graft human neural stem cells into monkeys with spinal cord injuries

Researchers demonstrate novel process to produce cell-sized lipid vesicles

Study finds novel therapeutic strategy that preserves neuromuscular synapses in ALS mouse model

Lab-grown cerebellar cells may help explain how ASD develops at molecular level

Alzheimer’s study on mice reveals important mechanism behind neural hyperactivity

Discovery offers fresh perspective on how the brain keeps its balance

Scientists uncover proteins in the brain responsible for movement

Caltech researchers develop new method to see neural connections in living flies

Key synaptic proteins could be targets for early interventions in patients with dementias

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The role of UV-Vis in biopharma QC

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