Whole Genome Sequencing News and Research

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Genetic cause of lupus identified

An international team of researchers has identified DNA mutations in a gene that senses viral RNA, as a cause of the autoimmune disease lupus, with the finding paving the way for the development of new treatments.

27 Apr 2022

Researchers identify five types of bacteria in men with aggressive prostate cancer

Researchers at the University of East Anglia have found a link between bacteria and aggressive forms of prostate cancer.

25 Apr 2022

Species differences in somatic mutations shed light on aging

A recent study published in the journal Nature aimed to elucidate, through a comparative analysis, the diversity in mutagenesis across different species, and the long-established hypothesis regarding evolution in the rates of somatic mutation, as well as their role in cancer and aging.

25 Apr 2022

Discovering Genetic Variants that Significantly Predispose People to Critical COVID-19

We speak with postdoctoral researcher Erola Pairo-Castineira about her recent work which aimed to find the genetic factors that may predispose individuals to critical COVID-19 and learn how COVID-19 affects cells in the body.

22 Apr 2022

Could DNA be linked to Premature Aging in Cancer Survivors?

In this interview, we speak to Dr. Wang about his latest research that investigated accelerated aging in childhood cancer survivors and the underlying genetics causing this.

22 Apr 2022

DNA analysis of tumors uncovers a 'treasure trove' of clues about the causes of cancer

DNA analysis of thousands of tumors from NHS patients has found a 'treasure trove' of clues about the causes of cancer, with genetic mutations providing a personal history of the damage and repair processes each patient has been through.

21 Apr 2022

Association between SARS-CoV-2 Omicron viral load and vaccination history

Researchers analyzed the association between viral loads in SARS-CoV-2 Omicron variant infection and vaccination history.

21 Apr 2022

Study evaluates SARS-CoV-2 whole genome data from patients and staff in the VA Northeast Ohio Healthcare System

Researchers surveyed over 360 COVID-19 patients to characterize the SARS-CoV-2 genomic sequence diversity of individual infections.

21 Apr 2022

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Alzheimer's disease is marked by a loss of functional neurons in the brain. But what causes this loss? Through single-cell genome sequencing, researchers at Boston Children's Hospital, Brigham and Women's Hospital, and the Broad Institute show that people with Alzheimer's have an abundance of newly acquired mutations in their neurons - more than people of the same age without Alzheimer's, and enough to disable genes important to brain function.

20 Apr 2022

Study finds two doses of mRNA or ChAdOx1 vaccines provide excellent protection against severe outcomes of hospitalization and death

Researchers assessed the effectiveness of COVID-19 vaccines against related hospitalizations and death.

18 Apr 2022

Epidemiologic characteristics of SARS-CoV-2 Omicron and Delta variant infection cases in Cantabria, Spain

Researchers performed a comparative assessment of the key epidemiological characteristics such as secondary attack rates, transmission, serial interval, and incubation period of SARS-CoV-2 infections by the Omicron and Delta variants.

12 Apr 2022

Exploring vaccine effectiveness against SARS-CoV-2 Omicron and Delta variants in adolescents

A new study assessed the effectiveness of the BNT162b2 SARS-CoV-2 vaccine against Delta and Omicron variants in adolescents.

12 Apr 2022

Immunocompromised hosts with Delta/Omicron co-infections

A recent study posted to the medRxiv* preprint server examined clinical cases of co-infections of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta/Omicron variants and Omicron BA.1/ BA.2 sublineages in immunocompromised (IC) patients.

10 Apr 2022

CDC report on Omicron infections soon after Delta

A new study identifies ten patients with confirmed SARS-CoV-2 Omicron variant infections within 90 days of a previous Delta variant infection.

10 Apr 2022

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

A variant of the CTLA-4 gene associated with autoimmune disease was found to be more frequent in non-small cell lung cancer (NSCLC) patients who experienced an exceptionally high response to anti-PD-1 immunotherapy and higher immune-related side effects than in a comparable cohort of lung cancer patients and healthy individuals, according to data presented during the AACR Annual Meeting 2022, held April 8-13.

10 Apr 2022

Whole Genome Sequencing News and Research

Genetic cause of lupus identified

Researchers identify five types of bacteria in men with aggressive prostate cancer

Species differences in somatic mutations shed light on aging

Discovering Genetic Variants that Significantly Predispose People to Critical COVID-19

Could DNA be linked to Premature Aging in Cancer Survivors?

DNA analysis of tumors uncovers a 'treasure trove' of clues about the causes of cancer

Association between SARS-CoV-2 Omicron viral load and vaccination history

Study evaluates SARS-CoV-2 whole genome data from patients and staff in the VA Northeast Ohio Healthcare System

Single-cell genome sequencing provides a new way to think about Alzheimer’s disease

Study finds two doses of mRNA or ChAdOx1 vaccines provide excellent protection against severe outcomes of hospitalization and death

Epidemiologic characteristics of SARS-CoV-2 Omicron and Delta variant infection cases in Cantabria, Spain

Exploring vaccine effectiveness against SARS-CoV-2 Omicron and Delta variants in adolescents

Immunocompromised hosts with Delta/Omicron co-infections

CDC report on Omicron infections soon after Delta

Study finds better immunotherapy response in lung cancer patients with genetic variant linked to autoimmune disease

Investigating high rate of Omicron sublineage breakthrough infections in triple vaccinated healthcare workers

Swedish HCW study shows COVID booster shots have limited effect on Omicron

Effectiveness of COVID-19 vaccines against hospitalization in those testing positive for Omicron and Delta variants

BNT162b2 booster vaccine provides equal protection against BA.1 and BA.2

TLR7 and MARK1 genomic variants impact COVID-19 prognosis

The art of CRISPR: The power and promise of gene editing eBook

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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