Central Nervous System News and Research

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Rituximab provides new hope for people with lupus

Rheumatologists at the Annual European Congress of Rheumatology in Vienna, Austria heard today (Thursday 9 June) that rituximab is the first drug in a quarter of a century that is making a real impact, and an alternative to previous standard treatments of high-dose steroids, and chemotherapy.

9 Jun 2005

Genetics may play a role in the effectiveness of chemotherapy drugs

Today, the most common childhood cancer is cured in about 80 percent of patients; only forty years ago, this number was closer to five percent. In efforts to further increase the survival rate, researchers from St. Jude Children's Research Hospital, the University of Tennessee, and the University of Chicago studied how an individual's genetics might play a role in the effectiveness of chemotherapy drugs.

3 Jun 2005

Targepeutics issued new U.S patent

Targepeutics has announced the issuance of U.S. Patent No. 6,884,603 for its genetically modified, mutated Interleukin 13 (IL-13) technology platform for the treatment of malignant glioma, a brain tumor (17,500 people annually; $200 million annual market).

31 May 2005

A sudden increase in the number of British cases of Lyme disease

Lyme disease, an infection carried by ticks causes a rash and stiffness in the joints and, if left unchecked, it can affect the central nervous system, causing tingling in hands and feet, or facial palsy. In the worst cases the disease can also affect the heart, liver and spleen and even lead to encephalitis, which can kill.

29 May 2005

Scientists watch agents of brain-wasting diseases invade and move within brain cells

Scientists for the first time have watched agents of brain-wasting diseases, called transmissible spongiform encephalopathies (TSE), as they invade a nerve cell and then travel along wire-like circuits to points of contact with other cells.

25 May 2005

Medical Research Council funds research to look at cannabis based medicines in multiple sclerosis treatment

A trial to determine whether cannabis-based medicines can reduce disability in patients with multiple sclerosis (MS) has been funded by the Medical Research Council (MRC).

24 May 2005

Dextromethorphan temporarily reduces the intensity of fibromyalgia

Dextromethorphan, an over-the-counter medication that silences coughs, may help fibromyalgia patients quiet over-reacting nerves that amplify ordinary touches into agony.

20 May 2005

Researchers prevent post-traumatic brain damage using experimental drug

In animal studies, researchers from Georgetown University Medical Center have shown how traumatic brain injury leads to loss of brain function - and found that an experimental drug can stop the damage and promote recovery.

18 May 2005

Changes in certain brain receptors can affect seizures and anxiety during the menstrual cycle

A new UCLA study shows that changes in certain brain receptors can affect seizures and anxiety during the menstrual cycle--findings that could lead to novel therapies for premenstrual dysphoric disorder (PMDD, formerly known as PMS) and other central nervous system symptoms associated with the menstrual cycle.

16 May 2005

Common antibiotic called minocycline may slow or prevent diabetic retinopathy

The team found that minocycline, often used to treat acne, limits by about 50 percent the retinal damage caused by microglia. Microglia are cells that act as the "cleanup crew" for the Central Nervous System (CNS).

11 May 2005

Discovery reveals how stem cells can be used to help repair acute spinal cord damage

A treatment derived from human embryonic stem cells improves mobility in rats with spinal cord injuries, providing the first physical evidence that the therapeutic use of these cells can help restore motor skills lost from acute spinal cord tissue damage.

10 May 2005

Symptoms of concussion may increase when the outcome of a lawsuit is at stake

The condition known as “postconcussional syndrome” is difficult to define medically but is generally defined as a string of cognitive, physical or behavioral losses that occur after a head injury.

1 May 2005

Antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system

By studying animals, Johns Hopkins researchers have discovered that the antibiotic minocycline might help alleviate HIV's negative effects on the brain and central nervous system, problems that can develop even though antiretroviral therapy controls the virus elsewhere in the body.

1 May 2005

National study to evaluate the effectiveness Targacept

Wake Forest University School of Medicine is one of 15 centers nationwide recruiting participants for a research study to evaluate the effectiveness of an investigational drug as an oral treatment for age associated memory impairment (AAMI), a condition that is marked by memory loss and poor concentration.

27 Apr 2005

Promising new West Nile therapy cures disease in mice

West Nile virus alarmed Americans when it made its first U.S. appearance in New York City in 1999. It has since spread from coast to coast, sickened more than 16,000 Americans and killed more than 600.

27 Apr 2005

Guidelines for research involving human embryonic stem cells

The National Academies today recommended guidelines for research involving human embryonic stem cells, and urged all institutions conducting such research to establish oversight committees to ensure that the new guidelines will be followed.

26 Apr 2005

Antibody for West Nile virus shows promise

Researchers have developed an antibody that can cure mice of West Nile virus (WNV) infection, a disease for which no specific treatment exists, the National Institute of Allergy and Infectious Diseases (NIAID) has announced.

25 Apr 2005

Cigarette smoking may contribute to the progression of multiple sclerosis

Researchers from the Harvard School of Public Health (HSPH) recently discovered that cigarette smoking may contribute to the progression of multiple sclerosis (MS), suggesting that quitting smoking could limit or delay central nervous system deterioration.

20 Apr 2005

Why different tissues in the human body vary in their susceptibility to "amyloid" diseases

Researchers at The Scripps Research Institute are reporting the results of a recent study that addresses why different tissues in the human body vary in their susceptibility to "amyloid" diseases, which include Alzheimer's disease and a cluster of ailments called the familial amyloidoses.

7 Apr 2005

Osteoporosis drug reduces women's risk of mild cognitive impairment

A drug prescribed for the prevention of osteoporosis reduced women's risk of mild cognitive impairment by 33 percent in a worldwide clinical trial led by researchers at San Francisco VA Medical Center (SFVAMC).

6 Apr 2005