Efficacy News and Research

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In the wake of Chantix's recall, Varenicline use for nicotine dependence dropped by 75%

The recent JAMA Network Open study evaluated how the Chantix recall influenced prescribing varenicline and other nicotine dependency medications. For this cross-sectional study, a large US-based national cohort was used. All relevant data between January 1, 2021, and June 30, 2022, was obtained from the national pharmacy benefit database.

7 Feb 2023

UC researcher aims to develop better treatments for KRAS-mutated pancreatic cancer

Pancreatic cancer diagnoses are increasing more rapidly than any other cancer type while remaining one of the most deadly cancers.

7 Feb 2023

AI can be a powerful tool to help identify lung nodules on chest X-rays

In a pioneering, randomized controlled study evaluating the effect of artificial intelligence (AI)-based software in real clinical practice, researchers found that AI significantly improved the detection of lung nodules on chest X-rays.

7 Feb 2023

Understanding the relationship between SARS-CoV-2 infection and periodontitis

In a recent review published in the journal International Journal of Molecular Sciences, researchers reviewed existing data on the association between periodontitis and coronavirus disease 2019 (COVID-19).

7 Feb 2023

Mucoactive drugs block SARS-CoV-2 infection

Researchers evaluate the effects of mucociliary active molecules on SARS-CoV-2 infection in vitro.

7 Feb 2023

How does vaping affect your health?

According to the significant review, using nicotine e-cigarettes increases the risk of various adverse health outcomes, especially in youth, including taking up smoking, addiction, poisoning, seizures, burns, and lung injury.

6 Feb 2023

Gut hormone receptor polyagonists show promise for obesity and diabetes

A new paper in the Journal of Clinical Investigation describes drugs that could help lose weight and manage type 2 diabetes mellitus (T2DM).

6 Feb 2023

Recent therapeutic strategies for renal cell carcinoma and the effects of the tumor microenvironment on systemic therapy

Researchers explored the association between the human microbiome and improved renal cell carcinoma outcomes.

6 Feb 2023

Virus Watch: A cohort study of COVID-19 in households of England and Wales

A new study posted on the pre-print medRxiv* aimed to discuss how Virus Watch provided public health approaches that were effective for the investigation of community incidence, symptom profiles, and the transmission of COVID-19, as well as the effectiveness of the COVID-19 vaccines.

5 Feb 2023

Experimental vaccine completely protects cynomolgus macaques against lethal Sudan virus

A National Institutes of Health research group with extensive experience studying ebolavirus countermeasures has successfully developed a vaccine against Sudan virus (SUDV) based on the licensed Ebola virus (EBOV) vaccine.

3 Feb 2023

The effectiveness of intranasal COVID-19 vaccination in healthy adults

A recent study discusses the safety profiles and immunogenicity of the nasal BBV154 COVID-19 vaccine in healthy adults.

3 Feb 2023

World Cancer Day 2023: Perspectives from The Institute of Cancer Therapeutics

To commemorate World Cancer Day, we spoke to a multidisciplinary team of researchers from The Institute of Cancer Therapeutics (ICT) based at the University of Bradford about their work in cancer research.

3 Feb 2023

Structural analysis of main protease from delta and gamma coronaviruses

A team of US-based scientists has recently determined the inhibitor-bound crystal structures of the Main proteases (Mpro) of delta and gamma coronaviruses isolated from mammals.

3 Feb 2023

The relationship between natural plant extracts and SARS-CoV-2

Researchers explored plants as an extensive resource of molecules with potential therapeutic action against SARS-CoV-2 and debunked misconceptions.

3 Feb 2023

Pitavastatin plus ezetimibe can help decrease blood lipid levels in patients with coronary heart disease

Announcing a new article publication for Cardiovascular Innovations and Applications journal. According to the findings of randomized controlled trials, blood lipid levels in patients with coronary heart disease (CHD) can be significantly decreased through a combination of pitavastatin and ezetimibe; however, the effects and clinical applications of this treatment remain controversial.

2 Feb 2023