Genes News and Research

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The role of exercise-induced hormone irisin in amyloid beta reduction

Researchers explored the biological mechanisms by which exercise-induced irisin attenuates amyloid-beta pathology in Alzheimer’s disease.

8 Sep 2023

UTSA researchers study the mechanism of action of Sweet Annie's medicinal compounds

Vibrant green leaves sprout from tall fragrant plants sitting neatly in two rows of terracotta pots in Valerie Sponsel's UTSA biology laboratory.

8 Sep 2023

Promising new cervical cancer test fills in the gap missed by Pap tests

Researchers assessed a novel human papillomavirus (HPV) and host deoxyribonucleic acid (DNA) methylation score for adenocarcinoma in-situ (AIS) and cervical adenocarcinoma (ADC) screening.

8 Sep 2023

NSAID use linked to higher risk of blood clots in women of reproductive age, association stronger in women on high-risk hormonal contraception

A new paper published in The BMJ explores the effect of these drugs used concomitantly on the risk of venous thromboembolism (VTE).

8 Sep 2023

Theabrownin from dark tea may have the potential to treat insulin resistance

The effects of theabrownin (TB) from dark tea treatment on insulin resistance (IR).

8 Sep 2023

Does caffeine interact with genetic risk factors for Parkinson's disease in Asians?

The interaction of caffeine with Leucine rich repeat kinase 2 (LRRK2) genetic risk variants in Asians.

8 Sep 2023

Study uncovers thousands of medication pairings linked to frequent dosage adjustments

Researchers investigated the complexity of polypharmacy and whether frequent dose adjustments were required for co-medications and drug pairs in hospital settings.

7 Sep 2023

Myriad Genetics survey: Women have widespread confusion and misconceptions about ovarian cancer screening

Myriad Genetics, Inc., a leader in genetic testing and precision medicine, today revealed new nationwide survey results indicating widespread confusion and misconceptions about ovarian cancer screening among a majority of women.

7 Sep 2023

New test could detect brain tumors using cerebrospinal fluid

Researchers with the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine and four other institutions have developed a molecular test to identify the presence of brain tumors by measuring abnormal genetic material shed by tumors and circulating in cerebrospinal fluid (CSF).

7 Sep 2023

VAI scientists uncover mechanism that annotates genetic information passed from fathers to offspring

Van Andel Institute scientists and collaborators have identified a key part of a mechanism that annotates genetic information before it is passed from fathers to their offspring.

7 Sep 2023

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Researchers performed a multi-omics evaluation of HSPCs obtained from individuals with myeloproliferative neoplasms transforming to TP53-related secondary forms of acute myeloid leukemia.

7 Sep 2023

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

In a recent study published in Nature, researchers investigated whether glutamatergic gliotransmission was mediated by specialized astrocytes in the central nervous system.

7 Sep 2023

People with traumatic brain injuries in earlier life may be at increased risk of late life cognitive decline

A study of twins shows that having a concussion early in life is tied to having lower scores on tests of thinking and memory skills decades later as well as having more rapid decline in those scores than twins who did not have a concussion, or traumatic brain injury (TBI).

7 Sep 2023

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Rochester Institute of Technology researchers are improving non-invasive treatment options for degenerative disc disease, an ailment that impacts 3 million adults yearly in the U.S., according to the Mayo Clinic.

6 Sep 2023

Study reveals heart failure insights at single-cell level

Researchers examined the cell-intrinsic effects of hematopoietic stem cells with somatic mutations in circulating cells from heart failure patients.

6 Sep 2023

Study identifies potential target for reversing drug resistance in ovarian cancer

For the 314,000 people diagnosed with ovarian cancer each year, hope often comes in the form of platinum-based drugs such as cisplatin.

5 Sep 2023

Cornell biologists shine light on the possible origin of differences in human social behaviors

Male fruit flies don't usually like each other. Socially, they reject their fellow males and zero in on the females they discern via chemical receptors – or so scientists thought.

5 Sep 2023

Sex hormones drive differences in male and female mouse kidneys

Female kidneys are known to be more resilient to disease and injury, but males need not despair. A new USC Stem Cell-led study published in Developmental Cell describes not only how sex hormones drive differences in male and female mouse kidneys, but also how lowering testosterone can "feminize" this organ and improve its resilience.

5 Sep 2023

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

Around 5.2% of the global population carries abnormal hemoglobin genes. Each year, 300,000 to 500,000 children are born with severe hemoglobinopathies worldwide, with approximately 80% of these cases occurring in developing countries.

5 Sep 2023

How SARS-CoV-2 hijacks Fragile X proteins to fuel infection: New clues in COVID-19 and genetic disorders

Study explores the interaction between SARS-CoV-2's non-structural protein 3 (NSP3) and proteins related to Fragile X mental retardation (FMRPs), shedding light on COVID-19 pathophysiology. The research suggests that the virus exploits these host cell proteins for effective infection and possibly interferes with antiviral defense mechanisms, offering new insights into the genetic basis of Fragile X syndrome.

5 Sep 2023

Genes News and Research

The role of exercise-induced hormone irisin in amyloid beta reduction

UTSA researchers study the mechanism of action of Sweet Annie's medicinal compounds

Promising new cervical cancer test fills in the gap missed by Pap tests

NSAID use linked to higher risk of blood clots in women of reproductive age, association stronger in women on high-risk hormonal contraception

Theabrownin from dark tea may have the potential to treat insulin resistance

Does caffeine interact with genetic risk factors for Parkinson's disease in Asians?

Study uncovers thousands of medication pairings linked to frequent dosage adjustments

Myriad Genetics survey: Women have widespread confusion and misconceptions about ovarian cancer screening

New test could detect brain tumors using cerebrospinal fluid

VAI scientists uncover mechanism that annotates genetic information passed from fathers to offspring

Chronic inflammation's influence on TP53 mutations in leukemia evolution explored in new study

Specialized astrocyte subpopulation discovery sheds light on brain health and treatment avenues

People with traumatic brain injuries in earlier life may be at increased risk of late life cognitive decline

RIT researchers use CRISPR to develop new treatment for degenerative disc disease

Study reveals heart failure insights at single-cell level

Study identifies potential target for reversing drug resistance in ovarian cancer

Cornell biologists shine light on the possible origin of differences in human social behaviors

Sex hormones drive differences in male and female mouse kidneys

NGS-based screening identifies rare and novel thalassemia mutations in Ganzhou, China

How SARS-CoV-2 hijacks Fragile X proteins to fuel infection: New clues in COVID-19 and genetic disorders

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