immunity News and Research

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SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Researchers from the US recently reported the preclinical development of a self-amplifying mRNA (SAM) vaccine that encodes a prefusion-stabilized SARS-CoV-2 spike glycoprotein.

12 Nov 2021

Immune responses with and without previous SARS-CoV-2 infection following single BNT162b2 vaccine dose

The Protective Immunity from T-cells to COVID-19 in Healthcare workers (PITCH) is a prospective, cohort, multi-center study enclosed within the SIREN study designed to assess the effectiveness of the BNT162b2 vaccine in healthcare workers.

12 Nov 2021

More than 11.4 million people in the UK receive COVID-19 booster jabs

The vital booster program has reached another milestone as more than 11.4 million people in the UK have now received their top-up jabs to maintain protection ahead of the winter months.

11 Nov 2021

New Delta sublineage shows no additional resistance to neutralization

Researchers are attempting to determine the ability of this new sublineage to avoid neutralization by antibodies elicited from vaccination.

11 Nov 2021

Immunity following COVID-19 vaccination and natural infection in India

The researchers evaluated immune response markers in a cross-section of people from the Indian state of West Bengal, including those vaccinated with either Covishield or Covaxin, the unvaccinated cohort, and the naturally infected.

11 Nov 2021

Corrected method for more accurate estimation of SARS-CoV-2 reproduction number

Scientists have recently proposed and applied a correction to EpiEstim, a statistical method to estimate the time-dependent transmission of infectious disease during an epidemic.

11 Nov 2021

Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

In an attempt to study the safety and effectiveness of sotrovimab in more vulnerable patients suffering from mild to moderate symptoms of COVID-19, a multinational team of researchers conducted the COVID-19 Monoclonal antibody Efficacy Trial-Intent to Care Early (COMET-ICE) trial.

11 Nov 2021

New discovery could lead to the creation of a pan-coronaviruses vaccine

Next generation vaccines for Covid-19 should aim to induce an immune response against 'replication proteins', essential for the very earliest stages of the viral cycle, concludes new research carried out by UCL scientists.

10 Nov 2021

Emergence of SARS-CoV-2 immune escape variants in an immunocompromised patient

A German case study recently published in the journal Nature Communications has characterized a long-term severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection dynamics in an immunosuppressed kidney transplant recipient and provided evidence for the evolution of SARS-CoV-2 into potentially harmful immune escape mutants during persistent infections.

10 Nov 2021

Global progress toward measles elimination continues to decline amidst the pandemic

While reported measles cases have fallen compared to previous years, progress toward measles elimination continues to decline and the risk of outbreaks is mounting, according to a new report from the World Health Organization and U.S. Centers for Disease Control and Prevention.

10 Nov 2021

The immune response elicited by an inactivated SAR-CoV-2 vaccine

A team of researchers assessed antibody responses to the inactivated SARS-CoV-2 vaccine among vaccine recipients in Shenzhen, China.

10 Nov 2021

How effective are mask-wearing and social distancing in UK universities?

A new paper describes the effects of various non-pharmaceutical interventions in dealing with the spread of this virus among students, faculty, and staff on university campuses following the reopening of these institutions.

10 Nov 2021

Mechanism of SARS-CoV-2 antibody transfer into breastmilk

A recent study aimed to understand better the mechanism of antibody transfer to breastmilk in the setting of SARS-CoV-2 infection.

10 Nov 2021

How one health center is leading Chicago on kid covid shots

As the medical assistant put on rubber gloves and readied the syringe, 5-year-old Victoria Macias, wearing a pink Minnie Mouse mask and white blouse, turned her head away and closed her eyes.

10 Nov 2021

Finnish study highlights the need for mRNA COVID vaccine booster shots

A register-based cohort study of the effectiveness of COVID-19 vaccines was performed to help decision-making on providing booster doses to social and healthcare workers (HCWs) like nurses, physicians, dentists, and other professionals in Finland. In addition, it estimated the vaccine effectiveness after the second dose. This study is published on the medRxiv* preprint server.

9 Nov 2021

COVID-19 vaccination strategies that minimize R0 may offer greater protection to vulnerable age groups

In this study, researchers aimed at finding the minimum vaccination rate for each age group that guaranteed the basic reproduction number R0 was less than 1, thus stabilizing the dynamics at the disease-free equilibrium.

9 Nov 2021

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

A new study explores the potential of MV-based vaccines targeting the S protein of SARS-CoV-2.

9 Nov 2021

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

Leonard Imbula of the Healthy Mind Lab at Washington University School of Medicine in St. Louis holds a bottle of fluvoxamine, a psychiatric drug that has been shown, in a pair of studies conducted on two continents, to be an effective treatment for people sick with COVID-19.

9 Nov 2021

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

The current analysis indicates that cTfh cells react to the spike antigen following vaccination are associated with anti-S protein neutralizing antibodies.

9 Nov 2021

Pregnant women’s humoral response is dependent on SARS-CoV-2 strain

The current study from Israel discusses the change in antibody response with the trimester of infection and the infecting variant.

9 Nov 2021

immunity News and Research

SARS-CoV-2 self-amplifying mRNA vaccine demonstrates cellular and humoral immune responses

Immune responses with and without previous SARS-CoV-2 infection following single BNT162b2 vaccine dose

More than 11.4 million people in the UK receive COVID-19 booster jabs

New Delta sublineage shows no additional resistance to neutralization

Immunity following COVID-19 vaccination and natural infection in India

Corrected method for more accurate estimation of SARS-CoV-2 reproduction number

Effectiveness of sotrovimab demonstrated in patients with mild to moderate COVID-19

New discovery could lead to the creation of a pan-coronaviruses vaccine

Emergence of SARS-CoV-2 immune escape variants in an immunocompromised patient

Global progress toward measles elimination continues to decline amidst the pandemic

The immune response elicited by an inactivated SAR-CoV-2 vaccine

How effective are mask-wearing and social distancing in UK universities?

Mechanism of SARS-CoV-2 antibody transfer into breastmilk

How one health center is leading Chicago on kid covid shots

Finnish study highlights the need for mRNA COVID vaccine booster shots

COVID-19 vaccination strategies that minimize R0 may offer greater protection to vulnerable age groups

A measles-vectored COVID-19 vaccine induces strong immunity in animal model

Psychiatric drug prevents some of the most serious complications of COVID-19, study finds

The role of T follicular helper cells in the humoral immune response to SARS-CoV-2

Pregnant women’s humoral response is dependent on SARS-CoV-2 strain

Exploring Strategies for Targeting Kinases in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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