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Discovery sheds light on how forces outside of cells get translated into internal signals

Johns Hopkins researchers used suction to learn that individual "molecular muscles" within cells respond to different types of force, a finding that may explain how cells "feel" the environment and appropriately adapt their shapes and activities.

21 Oct 2013

Anergis reports immunology data from AllerT Phase IIb study for birch pollen allergy

Anergis, a company focusing on proprietary allergy vaccines, today reported immunology data from the Phase IIb study of its lead compound AllerT.

21 Oct 2013

New investigational drug offers potential treatment option for lung cancer

PF-06463922, an investigational drug being developed by Pfizer Inc., has the potential to become a new treatment option for patients who have lung cancer harboring abnormalities in the ALK gene, according to preclinical results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

21 Oct 2013

Certain food and lifestyle habits can turn on or off expression of cancer related genes

Research performed at the Center of Research and Advanced Studies (Cinvestav) has identified that certain food and lifestyle habits can turn on or off the expression of cancer related genes.

21 Oct 2013

Hereditary high blood cholesterol overlooked and untreated worldwide

Hereditary high blood cholesterol leads to premature heart disease. It is overlooked and untreated virtually worldwide -- including in Europe. This is a major problem as the disease is dangerous for health. However, this disease is easy to diagnose and treat, according to the conclusion of a consensus report from the European Atherosclerosis Society.

21 Oct 2013

Genetic mutation found to restore translational balance in mice

In a biological quirk that promises to provide researchers with a new approach for studying and potentially treating Fragile X syndrome, scientists at the University of Massachusetts Medical School (UMMS) have shown that knocking out a gene important for messenger RNA (mRNA) translation in neurons restores memory deficits and reduces behavioral symptoms in a mouse model of a prevalent human neurological disease.

21 Oct 2013

Scientists find unexpected molecular switch that prompts blood stem cells aging

Scientists report in Nature they have found a novel and unexpected molecular switch that could become a key to slowing some of the ravages of getting older as it prompts blood stem cells to age.

21 Oct 2013

Study finds inherited GATA3 gene variation increases risk of developing pediatric leukemia

Research led by St. Jude Children's Research Hospital scientists has linked an inherited gene variation to a nearly four-fold increased risk of developing a pediatric acute lymphoblastic leukemia (ALL) subtype that is associated with a poor outcome.

21 Oct 2013

Tips to overcome feelings of discouragement or blues

Whether it is simply waking up on the wrong side of the bed or a bad week at work, many situations may trigger an onset of the blues. One University of Alabama at Birmingham mental health expert says feeling down is a form of depression and should be addressed.

19 Oct 2013

Community health awareness delivered by paramedics leads to 32% reduction in EMS calls

Emergency Medical Service (EMS) staff are accustomed to responding to emergencies. A study presented today at the Canadian Cardiovascular Congress finds they may be able to prevent many emergencies as well, judging by the preliminary success of a pilot project at a Hamilton building for seniors.

19 Oct 2013

Five Research Units established to uncover physiological basis for cognitive processes, cultural techniques

The Deutsche Forschungsgemeinschaft (DFG, German Research Foundation) is establishing five new Research Units. This was decided by the DFG Senate at its October meeting. The purpose of the research collaborations is to offer researchers the possibility to pursue current, pressing issues in their subject areas and to establish innovative work directions.

19 Oct 2013

New study guides clinicians and policy makers on cost-effectiveness of anticoagulant drugs

Patients who are responding below par to the anticoagulant drug warfarin have several options. They can undergo even more blood tests to monitor their response to the different dosages of this medication which is prescribed to prevent strokes, or they could start using one of the newer, yet more expensive, anticoagulants on the market.

19 Oct 2013

Research roundup: Less savings needed for retirement health expenses; falls as a predictor of surgical outcomes

Each week, KHN compiles a selection of recently released health policy studies and briefs.

19 Oct 2013

Study shows significant link between low dietary fiber intake and cardiometabolic risks

A new study published in the December issue of The American Journal of Medicine shows a significant association between low dietary fiber intake and cardiometabolic risks including metabolic syndrome, cardiovascular inflammation, and obesity.

19 Oct 2013

Opsumit drug receives FDA approval to treat adults with pulmonary arterial hypertension

The U.S. Food and Drug Administration today approved Opsumit (macitentan), a new drug to treat adults with pulmonary arterial hypertension (PAH), a chronic, progressive and debilitating disease that can lead to death or the need for lung transplantation.

19 Oct 2013

Schizophrenic hippocampal abnormalities blamed on glutamate

Elevated glutamate levels correlate with reduced tissue volume in the hippocampus of patients with schizophrenia, a study shows.

18 Oct 2013

Genalyte Gets Grant From NCI To Develop Biomarker Panel For Cancer

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18 Oct 2013

Ariad Ends Phase III Leukemia Drug Trial

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18 Oct 2013

Genalyte receives NCI grant to develop biomarker panel to profile TAA autoantibodies

Genalyte, Inc., today announced that it has received a $1 million SBIR grant from the National Cancer Institute to develop a biomarker panel to profile tumor antigen-associated autoantibodies.

18 Oct 2013

WHO calls on countries to eliminate lead poisoning that affects children globally

Lead poisoning has devastating health consequences, in particular for children, with childhood lead exposure estimated to contribute to 600 000 new cases of children with intellectual disabilities every year. Overall, 99% of children affected by high exposure to lead live in low- and middle-income countries, says WHO on the occasion of International Lead Poisoning Prevention Week of Action, and calls on countries to strengthen national actions to eliminate lead paint.

18 Oct 2013

Blood News and Research

Discovery sheds light on how forces outside of cells get translated into internal signals

Anergis reports immunology data from AllerT Phase IIb study for birch pollen allergy

New investigational drug offers potential treatment option for lung cancer

Certain food and lifestyle habits can turn on or off expression of cancer related genes

Hereditary high blood cholesterol overlooked and untreated worldwide

Genetic mutation found to restore translational balance in mice

Scientists find unexpected molecular switch that prompts blood stem cells aging

Study finds inherited GATA3 gene variation increases risk of developing pediatric leukemia

Tips to overcome feelings of discouragement or blues

Community health awareness delivered by paramedics leads to 32% reduction in EMS calls

Five Research Units established to uncover physiological basis for cognitive processes, cultural techniques

New study guides clinicians and policy makers on cost-effectiveness of anticoagulant drugs

Research roundup: Less savings needed for retirement health expenses; falls as a predictor of surgical outcomes

Study shows significant link between low dietary fiber intake and cardiometabolic risks

Opsumit drug receives FDA approval to treat adults with pulmonary arterial hypertension

Schizophrenic hippocampal abnormalities blamed on glutamate

Genalyte Gets Grant From NCI To Develop Biomarker Panel For Cancer

Ariad Ends Phase III Leukemia Drug Trial

Genalyte receives NCI grant to develop biomarker panel to profile TAA autoantibodies

WHO calls on countries to eliminate lead poisoning that affects children globally

Industry Focus eBook - Cell biology (5th edition) eBook

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

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