Protein News and Research

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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Take 2: What protein and where it is located are important for drug design

Drugs that target a single signaling pathway that drives tumor development and/or progression have been developed successfully to treat a few forms of cancer.

23 Feb 2009

Scientists identify lab-made proteins that neutralize a broad range of influenza A viruses

Scientists have identified a small family of lab-made proteins that neutralize a broad range of influenza A viruses, including the H5N1 avian virus, the 1918 pandemic influenza virus and seasonal H1N1 flu viruses.

23 Feb 2009

Significant Rett syndrome discovery

A paper published online today in Nature Neuroscience reveals the presence of methyl CpG binding protein 2 (MeCP2) in glia. MeCP2 is a protein associated with a variety of neurological disorders, including Rett Syndrome, the most physically disabling of the autism spectrum disorders.

23 Feb 2009

Mechanisms that prevent Alzheimer's Disease: Enzymatic activity plays key role

In a project involving the collaboration of several institutes, research scientists of the Johannes Gutenberg University Mainz have succeeded in gaining further insight in the functioning of endogenous mechanisms that protect against the development of Alzheimer's disease.

23 Feb 2009

Metastasis-promoting protein identified; could provide a prognostic test or target for breast cancer

Tumors that are about to progress and metastasize go through a process also seen in normal embryonic development, known as the epithelial to mesenchymal transition (EMT).

23 Feb 2009

Discovery of gene that controls the production of tooth enamel

Researchers have identified the gene that ultimately controls the production of tooth enamel, a significant advance that could some day lead to the repair of damaged enamel, a new concept in cavity prevention, and restoration or even the production of replacement teeth.

23 Feb 2009

Enhanced skin cancer risk linked to defects in cellular aging controls

Cell lifespan is limited by telomeres, DNA sequences that cap chromosomes and control the number of times a cell may be copied.

23 Feb 2009

Statins may lessen brain function

Research by an Iowa State University scientist suggests that cholesterol-reducing drugs known as statins may lessen brain function.

23 Feb 2009

Scientists shed light on how proteins find their shapes

Researchers from the California Institute of Technology (Caltech) and the University of California at San Diego (UCSD) have brought together UCSD theoretical modeling and Caltech experimental data to show just how amino-acid chains might fold up into unique, three-dimensional functional proteins.

23 Feb 2009

Redesign technique for proteins

Proteins are widely viewed as a promising alternative to synthetic chemicals in everything from medications to hand lotion.

23 Feb 2009

Oxford Nanopore announces publication of DNA analysis paper

Oxford Nanopore Technologies ("Oxford Nanopore") today announced the publication of new research in Nature Nanotechnology, demonstrating accurate and continuous identification of DNA bases using nanopores.

From Oxford Nanopore Technologies 23 Feb 2009

Better sequence searches of genes and proteins

Since the sequencing of the human genome eight years ago, enormous progress has been made in analyzing and understanding it. Nevertheless, the function of most human genes is still barely understood.

23 Feb 2009

Scientists identify lab-made proteins that neutralize multiple strains of seasonal and pandemic flu

22 Feb 2009

Scientists identify human monoclonal antibodies effective against bird flu

Researchers at the Dana-Farber Cancer Institute (Dana-Farber), Burnham Institute for Medical Research (Burnham) and the Centers for Disease Control and Prevention (CDC) have reported the identification of human monoclonal antibodies (mAb) that neutralize an unprecedented range of influenza A viruses, including avian influenza A (H5N1) virus, previous pandemic influenza viruses, and some seasonal influenza viruses.

22 Feb 2009

Calculating protein and gene connections in a Parkinson's model

Researchers have created an algorithm that meshes existing data to produce a clearer step-by-step flow chart of how cells respond to stimuli.

22 Feb 2009

Aching back? cholesterol drug Lovastatin might help

Back pain, a hallmark of degenerative disc disease, sends millions of people to their doctor. In fact, more than 80 percent of patients who undergo spine surgery do so because of disc degeneration.

22 Feb 2009

States expand newborn screening for life-threatening disorders

Regardless of where they are born in the United States, nearly all newborns now receive mandated screening for many life-threatening disorders, a remarkable public health advance of the last four years, according to a new report issued today by the March of Dimes.

20 Feb 2009