Clinical Trial News and Research

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Study evaluates efficacy of sarilumab in severe/critical COVID-19 patients

Researchers discuss the results of a clinical trial to assess the efficacy and safety of IV sarilumab for the treatment of hospitalized COVID-19 patients.

27 Mar 2022

New trial examines the effectiveness of a two-pronged immunotherapy for glioblastomas

A new clinical trial at the University of Cincinnati is studying the effectiveness of a new two-pronged immunotherapy treatment procedure to treat the most aggressive and deadly type of brain tumors, called glioblastomas. Originating from healthy brain cells, glioblastomas can form in any area of the brain.

25 Mar 2022

Family-based behavioral treatment improves weight-related outcomes in children with severe obesity

The FABO study showed that delivered at an obesity outpatient clinic, family-based behavioral treatment improved weight-related outcomes significantly more than treatment as usual among children aged 6-18 years with severe obesity.

25 Mar 2022

Tablet containing cannabidiol effectively reduces pain after shoulder surgery

An orally absorbed tablet containing cannabidiol (CBD) effectively reduces pain after shoulder surgery with no safety concerns, a new study finds.

25 Mar 2022

Reduced kidney function caused by antithrombotic therapy can influence bleeding events

Antithrombotic therapy is prescribed to prevent thrombotic (blood clotting inside a blood vessel) events but the treatment also increases the likelihood of experiencing a bleeding event, which can be extremely serious if it occurs in a vital organ.

25 Mar 2022

Study shows third dose of Pfizer-BioNTech vaccine against COVID-19 is both safe and effective

A research paper published in the New England Journal of Medicine has demonstrated how a third dose of Pfizer-BioNTech (BNT162b2) vaccine administered in a median period of 10.8 months after the second one bestowed 95.3% efficacy against coronavirus disease 2019 (COVID-19), in comparison with two doses of the same vaccine during a median follow-up of 2.5 months.

24 Mar 2022

Spinal fluid sampling could provide data about tumors sooner than MRIs

Treatment for glioma has long relied on MRI imaging to track tumor markers and treatment response.

24 Mar 2022

Study evaluates the prevalence of autoantibodies targeting type I interferons in critically-ill COVID-19 patients

Researchers assessed the prevalence of antibodies that neutralize the type I interferon antiviral activity and reactivate herpesviruses such as herpes simplex virus types 1 and 2 and/or cytomegalovirus infections in patients with critical COVID-19.

24 Mar 2022

World Tuberculosis Day 2022: an interview with Dr. Maxine Caws

For World Tuberculosis Day 2022, News Medical spoke to Dr. Maxine Caws to raise awareness of this infectious disease.

24 Mar 2022

Biomarker testing in lung cancer patients has increased in real-world clinical practice, study reveals

More than half of patients diagnosed with advanced non-small cell lung cancer (NSCLC) undergo biomarker testing, and this figure has increased over the last five years, reveal real-world data from a Spanish national registry study reported at the European Lung Cancer Congress, 30 March-2 April 2022.

23 Mar 2022

FDA approves new treatment for patients with metastatic melanoma based on Johns Hopkins research

The U.S. Food and Drug Administration has approved a novel therapy for patients with metastatic or inoperable melanoma, an aggressive type of skin cancer.

23 Mar 2022

Study finds lesser number of female principal investigators in cardiovascular clinical trials

Despite recent efforts to improve women's leadership in cardiovascular clinical trial research over the last decade, the number of female principal investigators (PIs) still falls well below the number of males leading similar heart studies, according to a study presented at the American College of Cardiology's 71st Annual Scientific Session.

23 Mar 2022

Study shows effectiveness of community-based group exercise program for older people with mobility limitations

Results from a major study into the effectiveness of a community-based group exercise program designed for people aged 65 and over with mobility limitations shows that REACT prevents physical decline and is cost-effective to run. The team behind it say it should be rolled out nationwide.

23 Mar 2022

Scientists identify a promising strategy for stopping Ebola virus polymerase

To treat Ebola virus infections, researchers are taking a close look at a key piece of the virus: polymerase.

23 Mar 2022

Novel nanoparticle-based COVID vaccines induce long-term neutralizing antibody response

Researchers report the results for a new SARS-CoV-2 vaccine currently in Phase III clinical trial known as I53-50.

22 Mar 2022

Daily consumption of cranberries for one month improves cardiovascular function

A new clinical trial found daily consumption of cranberries for one month improved cardiovascular function in healthy men.

22 Mar 2022

A psychedelic drug plus psychotherapy could help improve PTSD symptoms

Post-traumatic stress disorder (PTSD) affects millions of people each year, mostly survivors and witnesses of terrifying or shocking events, such as warfare, assaults or disasters. Because existing treatments don't work for everyone, new therapies are urgently needed.

22 Mar 2022

Study evaluates the effectiveness of lactobacilli throat sprays against COVID-19

A recent study evaluated the effectiveness of lactobacilli throat sprays against COVID-19.

22 Mar 2022

Closed Loop Medicine announces completion of precision medicine clinical trial for patients with high blood pressure

Closed Loop Medicine Ltd announced today that the last patient has completed participation in a clinical trial investigating the Company’s integrated precision care product solution for patients with hypertension.

22 Mar 2022

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

The findings of a new study suggest that a ketogenic diet - which is low in carbohydrates and protein, but high in fat - helps to kill pancreatic cancer cells when combined with a triple-drug therapy developed by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

22 Mar 2022

Clinical Trial News and Research

Study evaluates efficacy of sarilumab in severe/critical COVID-19 patients

New trial examines the effectiveness of a two-pronged immunotherapy for glioblastomas

Family-based behavioral treatment improves weight-related outcomes in children with severe obesity

Tablet containing cannabidiol effectively reduces pain after shoulder surgery

Reduced kidney function caused by antithrombotic therapy can influence bleeding events

Study shows third dose of Pfizer-BioNTech vaccine against COVID-19 is both safe and effective

Spinal fluid sampling could provide data about tumors sooner than MRIs

Study evaluates the prevalence of autoantibodies targeting type I interferons in critically-ill COVID-19 patients

World Tuberculosis Day 2022: an interview with Dr. Maxine Caws

Biomarker testing in lung cancer patients has increased in real-world clinical practice, study reveals

FDA approves new treatment for patients with metastatic melanoma based on Johns Hopkins research

Study finds lesser number of female principal investigators in cardiovascular clinical trials

Study shows effectiveness of community-based group exercise program for older people with mobility limitations

Scientists identify a promising strategy for stopping Ebola virus polymerase

Novel nanoparticle-based COVID vaccines induce long-term neutralizing antibody response

Daily consumption of cranberries for one month improves cardiovascular function

A psychedelic drug plus psychotherapy could help improve PTSD symptoms

Study evaluates the effectiveness of lactobacilli throat sprays against COVID-19

Closed Loop Medicine announces completion of precision medicine clinical trial for patients with high blood pressure

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

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