Pathogen News and Research

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Researchers hope to protect humans from another deadly outbreak like HIV

Throughout Asia, humans and monkeys live side-by side in many urban areas. An international research team from the University of Washington, Fred Hutchinson Cancer Research Center and Jahangirnagar University has been examining transmission of a virus from monkeys to humans in Bangladesh, one of the world's most densely populated countries.

5 Sep 2013

High-income and better hygiene countries exhibit much higher rates of Alzheimer's

New research has found a "very significant" relationship between a nation's wealth and hygiene and the Alzheimer's "burden" on its population. High-income, highly industrialised countries with large urban areas and better hygiene exhibit much higher rates of Alzheimer's.

5 Sep 2013

Affinium initiates dosing in Phase 1 IV clinical trial of antibiotic prodrug, AFN-1720

Affinium Pharmaceuticals announced today that it has initiated dosing in a Phase 1 intravenous clinical trial of its new antibiotic prodrug, AFN-1720. AFN-1720 is the prodrug of the active drug, AFN-1252.

5 Sep 2013

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Chronic granulomatous disease, or CGD, is a diverse group of inherited diseases in which certain cells of the immune system have difficulty forming reactive oxygen compounds, most importantly superoxide radicals. These are used by these white blood cells to kill certain bacteria.

3 Sep 2013

Research shows how mucosal surfaces in body respond to C. albicans to prevent damage

Candida albicans is a common fungus found living in, and on, many parts of the human body. Usually this species causes no harm to humans unless it can breach the body's immune defences, where can lead to serious illness or death.

3 Sep 2013

Researchers pinpoint ways to counter effects of antibiotics-driven depletion of gut-dwelling bacteria

A new study by researchers at the Stanford University School of Medicine could help pinpoint ways to counter the effects of the antibiotics-driven depletion of friendly, gut-dwelling bacteria.

2 Sep 2013

Researchers identify and track strains of antibiotic resistant salmonella

Continuing research on Salmonella may enable researchers to identify and track strains of antibiotic resistant bacteria as they evolve and spread, according to researchers in Penn State's College of Agricultural Sciences.

30 Aug 2013

Scientists reveal why TB is a successful pathogen

By any measure, tuberculosis is a wildly successful pathogen. It infects as many as two billion people in every corner of the world, with a new infection of a human host estimated to occur every second.

22 Aug 2013

Kentucky researcher uses advanced biomedical technology to study HMPV

You may not know the human metapneumovirus by name, but chances are that you have met somewhere before.

22 Aug 2013

Pre-doctoral students receive International Student Research Fellowships from HHMI

The Howard Hughes Medical Institute has awarded two doctoral students from the Sackler School of Graduate Biomedical Sciences at Tufts University with 2013 International Student Research Fellowships. Seblewongel Asrat, from Ethiopia, studies the bacterium that causes Legionnaires' disease while Jennifer Nwankwo, from Nigeria, studies red blood cell dehydration in sickle cell disease.

17 Aug 2013

Organizations are ill prepared for e-health implementation to respond to pandemic influenza

National and international organizations are ill-prepared to exploit e-health systems in the event of the emergence of a major pandemic disease, according to a research paper to be published in the International Journal of Biomedical Engineering and Technology.

17 Aug 2013

Study shows lymph node location influences maturation process of cells they contain

Based on their observations, the scientists deduced that lymph node location influences the maturation process of the cells they contain. "The cells retained their original skills for weeks following the transplant," says Dr. Sascha Cording, one of the study's first authors. "You might say lymph nodes have something like a location-specific memory."

17 Aug 2013

Spikes in Tsimane testosterone responsible for performing physically demanding task

The everyday physical activities of an isolated group of forager-farmers in central Bolivia are providing valuable information about how industrialization and its associated modern amenities may impact health and wellness.

14 Aug 2013

SIgN discovers strategy that cripples ability of dengue virus to escape host immune system

A new strategy that cripples the ability of the dengue virus to escape the host immune system has been discovered by A*STAR's Singapore Immunology Network (SIgN). This breakthrough strategy opens a door of hope to what may become the world's first universal dengue vaccine candidate that can give full protection from all four serotypes of the dreadful virus.

14 Aug 2013

Chemical compound prevents fungal cells from adhering to surfaces

Targeting serious and sometimes deadly fungal infections, a team of researchers at Worcester Polytechnic Institute (WPI) and the University of Massachusetts Medical School (UMMS) has discovered a chemical compound that prevents fungal cells from adhering to surfaces, which, typically, is the first step of the infection process used by the human pathogen Candida albicans (C. albicans).

14 Aug 2013

LMU immunologists develop new technique to fight against tumors, autoimmune diseases

Immunologists at Ludwig-Maximilians-Universitaet (LMU) in Munich have come up with a new technique that can be used both to fight tumors and to treat autoimmune diseases. A new grant from the Federal Ministry for Education and Research will enable the method to be developed further.

14 Aug 2013

Study: Strain of bacteria infections in humans originally come from cattle

A strain of bacteria that causes skin and soft tissue infections in humans originally came from cattle, according to a study to be published in mBio-, the online open-access journal of the American Society for Microbiology.

13 Aug 2013

Bacterial strains that delay cell division might be used to design drugs that stop division entirely

In 1958 a group of scientists working in Denmark made the striking observation that bacterial cells are about twice as large when they are cultured on a rich nutrient source than when they are cultured on a meager one.

13 Aug 2013

GE, UW scientists to develop new medical device for detecting infectious disease

You've heard of on-demand TV, now imagine on-demand medical diagnosis - anytime, anywhere in the world. Scientists at GE Global Research, the technology development arm of the General Electric Co. (NYSE: GE), are working with a team based at the University of Washington to develop a new medical device, the size of a pack of playing cards, that can detect infectious disease by way of a simple nasal swab, in less than an hour.

9 Aug 2013

Faecal contamination in natural pools due to droppings from birds

The use of natural pools - those that do not use chlorine or other chemical disinfection products - has seen an upward trend in recent years. Now, scientists from the University of Barcelona have discovered faecal contamination in some pools due to droppings from birds and other animals.

9 Aug 2013

Pathogen News and Research

Researchers hope to protect humans from another deadly outbreak like HIV

High-income and better hygiene countries exhibit much higher rates of Alzheimer's

Affinium initiates dosing in Phase 1 IV clinical trial of antibiotic prodrug, AFN-1720

Chronic granulomatous disease (CGD) research: an interview with Dr. Griffin Rodgers, NIDDK director

Research shows how mucosal surfaces in body respond to C. albicans to prevent damage

Researchers pinpoint ways to counter effects of antibiotics-driven depletion of gut-dwelling bacteria

Researchers identify and track strains of antibiotic resistant salmonella

Scientists reveal why TB is a successful pathogen

Kentucky researcher uses advanced biomedical technology to study HMPV

Pre-doctoral students receive International Student Research Fellowships from HHMI

Organizations are ill prepared for e-health implementation to respond to pandemic influenza

Study shows lymph node location influences maturation process of cells they contain

Spikes in Tsimane testosterone responsible for performing physically demanding task

SIgN discovers strategy that cripples ability of dengue virus to escape host immune system

Chemical compound prevents fungal cells from adhering to surfaces

LMU immunologists develop new technique to fight against tumors, autoimmune diseases

Study: Strain of bacteria infections in humans originally come from cattle

Bacterial strains that delay cell division might be used to design drugs that stop division entirely

GE, UW scientists to develop new medical device for detecting infectious disease

Faecal contamination in natural pools due to droppings from birds

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