Therapy News and Research

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Multigene test results impact physicians and patients' decisions on breast cancer therapy

A 21-gene test that predicts whether early stage breast cancer patients will benefit from chemotherapy is having a big impact on treatment decisions by patients and doctors alike.

12 Jan 2010

Proteinuria, a long accepted indicator of heart disease risk, has less impact on African-Americans compared to whites

The cardiovascular risk that is associated with proteinuria, or high levels of protein in the urine, a common test used by doctors as an indicator of increased risk for progressive kidney disease, heart attack and stroke, has race-dependent effects, according to a new study by researchers at Wake Forest University School of Medicine.

12 Jan 2010

GSK exercises option to obtain exclusive license to develop and commercialize Traficet-EN

GlaxoSmithKline (GSK) and ChemoCentryx, Inc. today announced that GSK has exercised its option to obtain an exclusive license for further development and worldwide commercialization of Traficet-EN(TM) (CCX282-B), a specific CCR9 antagonist with the potential to offer a new approach for the treatment of inflammatory bowel diseases, including Crohn's disease.

12 Jan 2010

Researchers study VA111913 drug as a possible treatment for dysmenorrhea

A leading clinical research center in Austin has joined an international research program to study an investigational drug designed as a possible treatment for painful menstrual cramps, or dysmenorrhea, a condition that affects between 45 and 90 percent of women of childbearing age in the United States.

12 Jan 2010

Antares Pharma, Population Council report positive Phase 2 results for novel NES/E2 contraceptive gel

Antares Pharma, Inc. and the Population Council today announced successful results from a dose-finding Phase 2 trial for a novel contraceptive gel containing the progestin Nestorone and estradiol (NES/E2) utilizing the Antares ATD (advanced transdermal delivery) gel system. Based on this successful data, the two parties continue to expect to partner with a worldwide or regional pharmaceutical company in order to commercialize this novel contraceptive gel.

12 Jan 2010

Cancer drug may provide an effective secondary treatment for gut tumor

A drug that is already an approved therapy for some cancers also might be an effective secondary treatment for a rare tumor of the gastrointestinal tract, according to a team led by researchers from the University of Pittsburgh Cancer Institute (UPCI). The findings, based on experiments using cell cultures, were published in the Jan. 1 issue of Cancer Research.

12 Jan 2010

Positive results from KemPharm's KP106 Phase 1 clinical trial for ADHD

KemPharm, Inc. today announced positive results from a Phase 1 clinical trial of KP106, its novel prodrug for attention-deficit hyperactivity disorder (ADHD). KP106, a new chemical entity (NCE) composed of the active pharmaceutical compound d-amphetamine and a ligand, was created using KemPharm’s proprietary Ligand Activated Therapy (LAT) prodrug approach.

12 Jan 2010

New therapeutic treatment may provide a potential alternative to bone grafting operation

A study published this week reinforces the potential value of stem cells in repairing major injuries involving the loss of bone structure.

12 Jan 2010

Interim results from Phase I clinical trials utilizing PLX-PAD for treatment of CLI reported

Pluristem Therapeutics Inc. today announced interim results from their Phase I clinical trials utilizing their placenta derived cell therapy product, PLX-PAD, for the treatment of critical limb ischemia (CLI), the end-stage of peripheral artery disease (PAD).

12 Jan 2010

PhotoMedex, Galderma Laboratories enter into co-promotion agreement for photodynamic therapy application

PhotoMedex and Galderma Laboratories, L.P. have entered into a co-promotion agreement for Galderma’s photodynamic therapy application for the treatment of actinic keratoses (“AK”).

11 Jan 2010

Targacept signs collaboration and license agreement with AstraZeneca

Targacept, Inc., a clinical-stage biopharmaceutical company developing a new class of drugs known as NNR Therapeutics™, today announced that its collaboration and license agreement with AstraZeneca for the global development and commercialization of TC-5214 for major depressive disorder (MDD) has become effective as a result of early termination of the waiting period under the Hart-Scott-Rodino Antitrust Improvements Act.

11 Jan 2010

New data from phase 3 study of avanafil for treatment of ED announced

VIVUS, Inc. today announced new data from an analysis of the recently completed phase 3 study (REVIVE TA-301) of avanafil, an investigational drug candidate for the treatment of erectile dysfunction (ED).

11 Jan 2010

Meda receives exclusive rights to distribute AML drug in Europe and Asia

Meda has in-licensed exclusive rights to Ceplene (histamine dihydrochloride) from EpiCept Corporation, a US-based biopharmaceutical company.

11 Jan 2010

EpiCept, Meda enter into exclusive commercialization agreement for Ceplene

EpiCept Corporation announced today that it has entered into an exclusive commercialization agreement for Ceplene® (histamine dihydrochloride) with Meda AB, a leading international specialty pharmaceutical company based in Stockholm. Ceplene is EpiCept’s novel therapy approved in the European Union with orphan drug status for the remission maintenance and prevention of relapse of patients with acute myeloid leukemia (AML) in first remission.

11 Jan 2010

Vertex Pharmaceuticals plans proof-of-concept clinical trials in RA and epilepsy

Vertex Pharmaceuticals Incorporated today provided an update on key 2010 business priorities in conjunction with the 28th Annual J.P. Morgan Healthcare Conference in San Francisco. The company also discussed recent progress in its lead development programs in hepatitis C virus (HCV) infection and cystic fibrosis (CF) and outlined proof-of-concept clinical trials planned in other serious diseases for 2010.

11 Jan 2010

Common brain tumour in children can arise from stem cells

New research from scientists at Queen Mary, University of London shows how the most common type of children's brain cancer can arise from stem cells.

11 Jan 2010

Interest in studying psychology on the rise

"I hope I will be able to touch the lives of people when they most need help and to offer them advice and guidance."

9 Jan 2010

EON Reality supports BBU with immersive EON Icube environment for virtual reality therapy project

EON Reality, the world's leading interactive 3D software provider, supports the Babes-Bolyai University (BBU), in Cluj-Napoca, Romania with an immersive EON Icube environment for a virtual reality therapy project.

9 Jan 2010

Gene therapy may help correct molecular flaws that cause brain disease

Neuroscientists have forged an unlikely molecular union as part of their fight against diseases of the brain and nervous system.

9 Jan 2010

Physiotherapy not "alternative" medicine or "voodoo", says CPA

The Canadian Physiotherapy Association (CPA) was surprised and dismayed to read articles in two of North America's most prestigious newspapers which question the use of certain commonly used physiotherapy treatments for musculoskeletal injuries. The articles, titled "Some physical therapy may be a stretch" and "Treat me, but no tricks please" suggest that ice, heat, ultrasound and other modalities are "voodoo" treatments.

9 Jan 2010

Therapy News and Research

Multigene test results impact physicians and patients' decisions on breast cancer therapy

Proteinuria, a long accepted indicator of heart disease risk, has less impact on African-Americans compared to whites

GSK exercises option to obtain exclusive license to develop and commercialize Traficet-EN

Researchers study VA111913 drug as a possible treatment for dysmenorrhea

Antares Pharma, Population Council report positive Phase 2 results for novel NES/E2 contraceptive gel

Cancer drug may provide an effective secondary treatment for gut tumor

Positive results from KemPharm's KP106 Phase 1 clinical trial for ADHD

New therapeutic treatment may provide a potential alternative to bone grafting operation

Interim results from Phase I clinical trials utilizing PLX-PAD for treatment of CLI reported

PhotoMedex, Galderma Laboratories enter into co-promotion agreement for photodynamic therapy application

Targacept signs collaboration and license agreement with AstraZeneca

New data from phase 3 study of avanafil for treatment of ED announced

Meda receives exclusive rights to distribute AML drug in Europe and Asia

EpiCept, Meda enter into exclusive commercialization agreement for Ceplene

Vertex Pharmaceuticals plans proof-of-concept clinical trials in RA and epilepsy

Common brain tumour in children can arise from stem cells

Interest in studying psychology on the rise

EON Reality supports BBU with immersive EON Icube environment for virtual reality therapy project

Gene therapy may help correct molecular flaws that cause brain disease

Physiotherapy not "alternative" medicine or "voodoo", says CPA

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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