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12 minutes of activity a day is all you need to reclaim maximum health

You're hitting the gym four to five times a week. You're dutifully doing the elliptical trainer or treadmill for an hour at a time. But all those long, boring workouts do nothing to strengthen your heart or slim your waistline. Do enough cardio and aerobics and you'll get old before your time.

16 Feb 2010

When blood sugar levels rise in healthy people, insulin signals cells to increase production: Study

In type 2 diabetes, which is occurring at alarming rates, the hormone insulin does not work effectively to lower blood sugars and patients also do not make enough insulin. These two processes have been widely considered as separate.

16 Feb 2010

TB's mechanism to evade body's immune system identified

Indiana University School of Medicine researchers have identified a mechanism used by the tuberculosis bacterium to evade the body's immune system and have identified a compound that blocks the bacterium's ability to survive in the host, which could lead to new drugs to treat tuberculosis.

16 Feb 2010

Study: sdNVP can lead to HIV treatment failure in women receiving drug to prevent infant infection

A new international study reported in PLoS Medicine confirms that a single dose of nevirapine (sdNVP) can lead to HIV treatment failure in women who receive the drug to prevent transmission of the AIDS virus to their infants. However, the increased risk of failure could only be detected in women who began full HIV treatment within about a year after receiving sdNVP.

16 Feb 2010

SimMan 3G robotic patient helps pharmacy students practice diagnostic skills

A robot that can be programmed to have a range of medical conditions, from heart disease to constipation, is being used by Pharmacy students at the University of Bath to help practise diagnostic skills and treating patients.

16 Feb 2010

Three Dutch life-science sectors announce joint investment to research on personalized medicine

The Netherlands' three Top Institutes for life-science research (the BioMedical Materials program, the Center for Translational Molecular Medicine and Top Institute Pharma) today announced a joint investment of MEUR 28 on innovative research targeted at bringing personalized medicine closer to reality.

16 Feb 2010

Use of non-steroidal anti-inflammatory drugs not associated with risk of squamous cell skin cancer

Contrary to previous hypotheses, the use of non-steroidal anti-inflammatory drugs does not appear associated with risk of squamous cell skin cancer, according to a report posted online today that will appear in the April print issue of Archives of Dermatology, one of the JAMA/Archives journals.

16 Feb 2010

NorTech announces winners of annual Innovation Awards program

NorTech, in partnership with Crain's Cleveland Business, is pleased to announce the winners of its annual Innovation Awards program which honors the achievements of Northeast Ohio's most innovative organizations and leaders.

16 Feb 2010

Researchers discover chemical compound to combat malaria and bacterial diseases

Researchers report that they have discovered - and now know how to exploit - an unusual chemical reaction mechanism that allows malaria parasites and many disease-causing bacteria to survive. The research team, from the University of Illinois, also has developed the first potent inhibitor of this chemical reaction.

16 Feb 2010

Researchers discover new mechanism within human cells that constantly protects against disease

Researchers at Oregon Health & Science University have discovered a new mechanism within human cells that constantly protects us against disease. P. Michael Conn, Ph.D., a researcher at the OHSU Oregon National Primate Research Center directed the work. The findings are reported in the Feb. 15 issue of the journal Proceedings of the National Academy of Sciences.

16 Feb 2010

Structure of 'DNA repair engine' that reverses beneficial effects of chemotherapy deciphered

Cancer Research UK scientists have deciphered the first structure of 'a DNA repair engine' that reverses the beneficial effects of chemotherapy, according to research published in Nature Structural and Molecular Biology* today.

15 Feb 2010

Research findings may open door to new therapeutic strategies for serious health problems

Drugs that target the way cells convert nutrients into energy could offer new approaches to treating a range of conditions including heart attack and stroke. Using a new way to screen for potential drugs, a team led by Massachusetts General Hospital (MGH) researchers has identified several FDA-approved agents, including an over-the-counter anti-nausea drug, that can shift cellular energy metabolism processes in animals.

15 Feb 2010

Isogenica enters into agreement with Dstl to develop antimicrobial peptide drugs

Isogenica Ltd today announced that it has entered into an agreement with UK Ministry of Defence agency, the Defence Science and Technology Laboratory. The agreement concerns the development of antimicrobial peptide drugs and follows a successful collaboration to identify highly effective antimicrobial peptides which are active against a broad spectrum of bacteria.

15 Feb 2010

Researchers identify defective signaling pathway that contributes to the severity of cystic fibrosis

In a study that could lead to new therapeutic targets for patients with the cystic fibrosis, a research team from the University of California, San Diego School of Medicine has identified a defective signaling pathway that contributes to disease severity.

15 Feb 2010

Researchers discover Dab2 protein that switches on EMT process

Reporting in Nature Cell Biology, researchers describe the discovery of a specific protein called disabled-2 (Dab2) that switches on the process that releases cancer cells from the original tumor and allows the cells to spread and develop into new tumors in other parts of the body.

15 Feb 2010

Wyoming lawkmaker pushes for reform, Mississippi Governor bans certain over-the-counter drugs

Associated Press/CNBC: "A veteran Wyoming state senator for the third time is pushing a bill he says would offer health insurance to people who couldn't afford it on the open market and also serve as an example to the rest of the nation of how to tackle rising health care costs. Sen. Charles Scott, R-Casper, has proposed a pilot program that calls for allowing 500 participants to enroll in Medicaid beginning in July. It would be limited to people whose family income is below 250 percent of the federal poverty level — $55,125 for a family of four.

15 Feb 2010

Polls: People like their own insurance but want reform, heart patients' cost worries

Lancaster Online: "Most Americans who have health insurance are pleased with their coverage, a new national Franklin & Marshall College poll shows. But many of those same people are worried about those who can't afford insurance, and overwhelmingly believe the health care system needs to be reformed, according to a survey of 920 adults. ... The survey found that 75 percent of Americans who have insurance rate their coverage as good or very good — the same percentage who believe the health-care system is in need of reform.

15 Feb 2010

Today's OpEds: Republicans and Medicare, small business health costs and changes to FEHBP

Republican leaders are now saying they will not participate in the meeting unless the president takes his health reform plan off the table to start over. I understand their concerns with a variety of issues in the current bills, but where you start is not nearly as important as where you finish. After all, fees continue to skyrocket and millions remain uninsured, costing our country in many ways. ... There is no time like the present for Washington to show America that it is interested in governing, not just in campaigning. The cameras will be rolling, and we will be watching (Christine Todd Whitman, 2/12).

14 Feb 2010

Viral Genetics: Company update

Our mission is to bring new drug compounds to the marketplace. And we've never been in a stronger position to deliver on that promise. We've built the solid foundation needed to take drug therapies from the laboratory to the marketplace. After years in development, we believe several of our most promising compounds are moving closer to clinical trials.

12 Feb 2010

HIV transmission among male partners: CFAR scientists discover origin of strains

A team of scientists, led by a virologist from the University of California, San Diego's Center for AID Research (CFAR), has discovered the origin of strains of human immunodeficiency virus (HIV) among men who have sex with men. The study, which may be important in developing prevention strategies for HIV, will appear in Science Translational Medicine on February 10, 2010.

12 Feb 2010

Drugs News and Research

12 minutes of activity a day is all you need to reclaim maximum health

When blood sugar levels rise in healthy people, insulin signals cells to increase production: Study

TB's mechanism to evade body's immune system identified

Study: sdNVP can lead to HIV treatment failure in women receiving drug to prevent infant infection

SimMan 3G robotic patient helps pharmacy students practice diagnostic skills

Three Dutch life-science sectors announce joint investment to research on personalized medicine

Use of non-steroidal anti-inflammatory drugs not associated with risk of squamous cell skin cancer

NorTech announces winners of annual Innovation Awards program

Researchers discover chemical compound to combat malaria and bacterial diseases

Researchers discover new mechanism within human cells that constantly protects against disease

Structure of 'DNA repair engine' that reverses beneficial effects of chemotherapy deciphered

Research findings may open door to new therapeutic strategies for serious health problems

Isogenica enters into agreement with Dstl to develop antimicrobial peptide drugs

Researchers identify defective signaling pathway that contributes to the severity of cystic fibrosis

Researchers discover Dab2 protein that switches on EMT process

Wyoming lawkmaker pushes for reform, Mississippi Governor bans certain over-the-counter drugs

Polls: People like their own insurance but want reform, heart patients' cost worries

Today's OpEds: Republicans and Medicare, small business health costs and changes to FEHBP

Viral Genetics: Company update

HIV transmission among male partners: CFAR scientists discover origin of strains

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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