Biomarker News and Research

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A biomarker is a biological molecule found in blood, other body fluids, or tissues that is a sign of a normal or abnormal process, or of a condition or disease. A biomarker may be used to see how well the body responds to a treatment for a disease or condition. Also called molecular marker and signature molecule.

PSMA PET imaging more precise than MR imaging for detection of high-grade prostate cancer lesions

A molecular imaging biomarker is able to detect fast-growing primary prostate cancer and distinguish it from benign prostate lesions, addressing an unmet clinical need. The new research, published in the July 2015 issue of The Journal of Nuclear Medicine, is significant for patients with suspected prostate cancer that has not been confirmed by standard biopsy.

21 Aug 2015

Landmark 'basket study' shows efficacy of vemurafenib in multiple nonmelanoma BRAFV600-mutated cancers

Researchers from Memorial Sloan Kettering Cancer Center have announced results from the first published basket study, a new form of clinical trial design that explores responses to drugs based on the specific mutations in patients' tumors rather than where their cancer originated.

20 Aug 2015

CSF biomarkers predict dementia risk in PD patients

Early analysis of cerebrospinal fluid could help diagnose parkinsonian disorders and enhance the prediction of dementia in Parkinson’s disease patients, study results indicate.

19 Aug 2015

UC Davis researchers set out to identify biomarkers for early diagnosis of lung cancer

Despite decades of warnings about smoking, lung cancer is still the second-most common cancer and the leading cause of death from cancer in the U.S. Patients are often diagnosed only when their disease is already at an advanced stage and hard to treat. Researchers at the West Coast Metabolomics Center at UC Davis are trying to change that, by identifying biomarkers that could be the basis of early tests for lung cancer.

19 Aug 2015

NIH grants Clinical and Translational Science Award to UC San Diego

The Clinical and Translational Research Institute (CTRI) at University of California, San Diego has received a five-year Clinical and Translational Science Award (CTSA) for approximately $52 million from the National Center for Advancing Translational Science, part of the National Institutes of Health.

19 Aug 2015

Researchers at Forsyth Institute enhance pipetting efficiency using VIAFLO Assist

INTEGRA reports on how researchers at the renowned Forsyth Institute (Cambridge, MA) are using a VIAFLO Assist to enhance the efficiency while maintaining the accuracy of pipetting protocols related to the discovery, measurement, and validation of new biomarkers of disease that can be found in saliva.

From INTEGRA Biosciences 18 Aug 2015

NCI-MATCH phase II precision medicine trial opens through ECOG-ACRIN

The National Cancer Institute-Molecular Analysis for Therapy Choice (NCI-MATCH) phase II precision medicine trial, known to doctors as trial EAY131, is open through the ECOG-ACRIN Cancer Research Group.

18 Aug 2015

Vitamin D supplements may help reduce risk of falls in homebound elderly

Every year falls affect approximately one in three older adults living at home, with approximately one in 10 falls resulting in serious injury. Even if an injury does not occur, the fear of falling can lead to reduced activity and a loss of independence.

18 Aug 2015

New research reveals effects of age on sleep quality

The elderly are doing something right. New research into the effects of age on sleep suggests our older community sleep less, but report better quality sleep, and feel more awake during the day.

17 Aug 2015

FAU neuroscientist develops Quick Dementia Rating System comparable to gold standard clinical tests

Determining whether or not an individual has dementia and to what degree is a long and laborious process that can take an experienced professional such as a clinician about four to five hours to administer, interpret and score the test results. A leading neuroscientist at Florida Atlantic University has developed a way for a layperson to do this in three to five minutes with results that are comparable to the "gold standard" dementia tests used by clinicians today.

13 Aug 2015

New research could help develop precision medicine for primary aldosteronism

Each of your kidneys wears a little yellow cap that helps keep your blood pressure in check, and much more. But in some people, it starts running amok, pumping out a hormone that sends blood pressure sky-high.

13 Aug 2015

New approach may offer improved way to detect early breast cancer

Researchers have shown that magnetic resonance imaging (MRI) can detect the earliest signs of breast cancer recurrence and fast-growing tumors. Their approach detects micromestastases, breakaway tumor cells with the potential to develop into dangerous secondary breast cancer tumors elsewhere in the body.

12 Aug 2015

Researcher study potential biomarker to determine patients at risk for aggressive breast cancer

Biomarkers are an important part in detecting certain cancers such as the BRCA gene in breast cancer and the PSA antigen in prostate cancer. They are easy to identify in a blood test and can help in diagnosing and giving a prognosis.

12 Aug 2015

Breath analysis shows potential biomarkers for early-stage diagnosis of liver disease

A natural compound called limonene, which is found in oranges and lemons, could be indicative in early-stage diagnosis of liver disease, according to research published in the journal EBioMedicine by researchers in the Molecular Physics Group at the University of Birmingham.

12 Aug 2015

Biomarker News and Research

Further Reading

PSMA PET imaging more precise than MR imaging for detection of high-grade prostate cancer lesions

Landmark 'basket study' shows efficacy of vemurafenib in multiple nonmelanoma BRAFV600-mutated cancers

CSF biomarkers predict dementia risk in PD patients

UC Davis researchers set out to identify biomarkers for early diagnosis of lung cancer

NIH grants Clinical and Translational Science Award to UC San Diego

Researchers at Forsyth Institute enhance pipetting efficiency using VIAFLO Assist

NCI-MATCH phase II precision medicine trial opens through ECOG-ACRIN

Vitamin D supplements may help reduce risk of falls in homebound elderly

New research reveals effects of age on sleep quality

FAU neuroscientist develops Quick Dementia Rating System comparable to gold standard clinical tests

New research could help develop precision medicine for primary aldosteronism

New approach may offer improved way to detect early breast cancer

Researcher study potential biomarker to determine patients at risk for aggressive breast cancer

Breath analysis shows potential biomarkers for early-stage diagnosis of liver disease

Aerobic exercise can help reduce excessive daytime sleepiness among depressed people

VolitionRx reports net loss of $1.9 million for second quarter 2015

CSN6 protein linked to poor survival among patients with colorectal cancer

New technology that tracks patients' eye movements may accurately measure brain injury

Early cognitive changes linked to white matter damage in Parkinson’s

Genetic test may help identify better treatment option for HER2-positive breast cancer patients

Industry Focus eBook - Protein Analysis (3rd edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

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