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Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

A new study has focussed on assessing the Mpro mutants of newly emerged SARS-CoV-2 variants.

2 Dec 2021

Novel approach to estimate transmission advantage of SARS-CoV-2 variants in real-time

A new study retrospectively estimates the effective transmission advantage of the Alpha variant as compared to other non-VOC lineages.

1 Dec 2021

Plant-derived virus-like particle vaccines against SARS-CoV-2

In a review published in Biotechnology Letters, the authors discuss plant-derived VLP-based vaccines.

1 Dec 2021

Novel nanopore technique for annotation of SARS-CoV-2 capping sites and understanding sgRNA structure

New research examined SARS-CoV-2 transcripts in order to understand how it expresses its gene products in the infected host.

1 Dec 2021

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

With the world still in the grip of a devastating pandemic, it's hard to imagine viruses as something other than hostile enemies to be vanquished.

30 Nov 2021

Scientists identify a new therapeutic target for HIV

Scientists in Montreal and London have identified the key role played by transcription factorRORC2 in HIV infection: the molecule attaches itself to parts of the virus's genome yet doesn't prevent it from replicating.

30 Nov 2021

Host and in vitro genomic variability of SARS-CoV-2 and its variants

Researchers from the University of Sydney investigate the genomic variability of SARS-CoV-2 within the host and in vitro.

30 Nov 2021

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

A new paper deals with the identification of an antiviral compound that could help in developing additional drugs to help fight COVID-19.

30 Nov 2021

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

In the largest genetic study of suicide attempts to date, researchers have identified a region of the genome on chromosome 7 containing DNA variations that increase the risk that a person will attempt suicide.

30 Nov 2021

Targeted measures to prevent the spread of Omicron variant take effect from 30 November 2021

Targeted measures to prevent the spread of the new COVID-19 Omicron variant take effect from 4am today [Tuesday 30 November].

29 Nov 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

Researchers study human single nucleotide variants (SNVs) using machine learning to identify amino acid changes that alter kinase-bound sequence motifs.

29 Nov 2021

An update of what is currently known about Omicron

On 26 November 2021, WHO designated the variant B.1.1.529 a variant of concern, named Omicron, on the advice of WHO's Technical Advisory Group on Virus Evolution (TAG-VE).

29 Nov 2021

UC San Diego's Scott Lippman to launch and lead NCI-sponsored PreCancer Genome Atlas

Scott Lippman, MD, will launch and lead the PreCancer Genome Atlas, a National Cancer Institute (NCI)-sponsored effort to map in time and space all of the molecular, cellular and structural characteristics of premalignant lesions and how they evolve into invasive cancers.

29 Nov 2021

Extended host range for SARS-CoV-2 variants of concern

Researchers used viral pseudotyping to examine whether variants of concern had different host ACE2 receptor usage patterns.

29 Nov 2021

Immunity found 6 months after SARS-CoV-2 infection in children

A new study suggests that infection-induced antibodies persist, providing protection for at least six months.

29 Nov 2021

Immunogenicity of modified microparticle-adjuvanted SARS-CoV-2 vaccine

Researchers investigated the immunogenicity of a novel adjuvant comprised of a modified porous silicon microparticle for the SARS-CoV-2 S protein RBD subunit vaccine.

29 Nov 2021

Identifying the spread of novel B.1.1.523 SARS-CoV-2

In their recent study, researchers from Lithuania have reported the emergence of a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant lineage B.1.1.523 containing a set of mutations associated with immune escape, including deletion 156_158del, substitution E484K and S494P in Spike (S) protein.

28 Nov 2021

Genome News and Research

Study suggests efficacy of SARS-CoV-2 main protease inhibitors is not compromised in current COVID-19 variants

Novel approach to estimate transmission advantage of SARS-CoV-2 variants in real-time

Plant-derived virus-like particle vaccines against SARS-CoV-2

Novel nanopore technique for annotation of SARS-CoV-2 capping sites and understanding sgRNA structure

Review highlights oncolytic viruses with remarkable ability to destroy cancer cells

Scientists identify a new therapeutic target for HIV

Host and in vitro genomic variability of SARS-CoV-2 and its variants

Structure-guided virtual screening identifies novel SARS-CoV-2 Mpro inhibitors

Researchers dissect the shared genetic architecture of suicide attempts and psychiatric disorders

Targeted measures to prevent the spread of Omicron variant take effect from 30 November 2021

Genetic variations affect and rewire phosphorylation signaling networks in SARS-CoV-2 infection

An update of what is currently known about Omicron

UC San Diego's Scott Lippman to launch and lead NCI-sponsored PreCancer Genome Atlas

Extended host range for SARS-CoV-2 variants of concern

Immunity found 6 months after SARS-CoV-2 infection in children

Immunogenicity of modified microparticle-adjuvanted SARS-CoV-2 vaccine

Identifying the spread of novel B.1.1.523 SARS-CoV-2

Study finds no evidence to support favipiravir use in mild or asymptomatic COVID-19 patients

The introduction and rapid spread of SARS-CoV-2 Gamma in Venezuela

SARS-CoV-2 Omicron variant: What we know so far

The art of CRISPR: The power and promise of gene editing eBook

Lab Matters host Harriet Gould on building a more connected lab community

The Critical Role of Sample Storage in Drug Discovery and Development

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

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