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Wastewater clues could revolutionize Alzheimer's detection

Review explores the potential of wastewater-based epidemiology (WBE) for diagnosing Alzheimer's disease (AD) through biomarkers in biofluids, offering a non-invasive, cost-effective approach to early detection and large-scale monitoring.

18 Feb 2024

New study pinpoints key markers for Long COVID diagnosis

Study identifies elevated serologic responses and memory CD8+ T cell clonal expansion as key markers of Long COVID, offering insights into its pathology and potential diagnostic approaches.

18 Feb 2024

Exome sequencing unravels complex genetic diagnoses in growth disorders

In an article published in the Journal of Pediatrics, researchers based in Brazil describe the case of a nine-year-old boy admitted to hospital with multiple symptoms and overlapping conditions that made diagnosis difficult, such as short stature, thin tooth enamel (dental enamel hypoplasia), moderate mental deficiency, speech delay, asthma, mildly altered blood sugar, and a history of recurring infections in infancy.

16 Feb 2024

Researchers introduce a pioneering approach to combat neurodegenerative diseases

Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Amyotrophic lateral sclerosis (ALS).

16 Feb 2024

Innovative immunotherapy targets rare melanoma subtypes

Scientists at the UCLA Health Jonsson Comprehensive Cancer Center have built and demonstrated the potential efficacy of a new chimeric antigen receptor (CAR) T-cell-based immunotherapy specifically designed to treat patients with cutaneous and rare subtypes of melanoma.

16 Feb 2024

Study suggests patients with severe long COVID present with variable symptoms, do not cluster in relation to organs affected or immunological states

A new preprint reports significantly associated findings that may help predict severe long COVID and understand what causes it.

16 Feb 2024

Researchers discover protein key to toxoplasmosis pathogen multiplication

Researchers have identified a protein that evolved concurrently with the emergence of cellular compartments crucial for the multiplication of the toxoplasmosis pathogen.

16 Feb 2024

A plant-based diet and its relationship with oxidative biomarkers in footballers

Researchers investigated the association between plant-based diets and oxidative biomarkers by calculating the plant-based diet index score and determining the levels of urinary biomarkers for oxidative stress in professional footballers.

16 Feb 2024

Researchers develop new way to make vegan food more appetizing

Vegan food is often sidestepped due to its rubbery consistency. Food technology researchers at Lund University in Sweden have now developed a way to make vegan food more appetizing by using new combinations of raw materials.

16 Feb 2024

AI revolutionizes protein function prediction with "DeepGO-SE"

Researchers developed "DeepGO-SE," a novel AI method for predicting protein functions from sequences, significantly outperforming traditional models by incorporating gene ontology and protein-protein interactions.

15 Feb 2024

Novel splicing mechanism for short introns discovered

Researchers confirm that the established pre-mRNA splicing mechanism that appears in textbooks cannot work in a subset of human short introns: A novel SAP30BP–RBM17 complex-dependent splicing has been uncovered.

15 Feb 2024

Ketogenic diet boosts brain's natural calm to combat epilepsy

A study in Cell Discovery shows the ketogenic diet increases brain GABA levels and the GABA/glutamate ratio through β-hydroxybutyric acid, offering a potential mechanism for its effectiveness in reducing epilepsy seizures.

15 Feb 2024

Novel synthetic antibiotic effective against drug-resistant bacteria

A new antibiotic created by Harvard researchers overcomes antimicrobial resistance mechanisms that have rendered many modern drugs ineffective and are driving a global public health crisis.

15 Feb 2024

Innovative treatment increases survival of people with malignant mesothelioma, trial shows

An innovative treatment significantly increases the survival of people with malignant mesothelioma, a rare but rapidly fatal type of cancer with few effective treatment options, according to results from a clinical trial led by Queen Mary University of London.

15 Feb 2024

Experts join forces to define recommendations for biomarker-based diagnosis of Alzheimer’s disease

A multidisciplinary working group of 22 experts from eleven European scientific associations have joined forces to define recommendations for the effective and individualized use of biomarkers for the diagnosis of Alzheimer’s disease in memory clinics.

15 Feb 2024

How maternal diet composition influences offspring appetite and metabolic health

Researchers evaluated the impact of maternal dietary protein and carbohydrate balance on offspring's appetite and metabolic health.

15 Feb 2024

Study explores health benefits of selenium and zinc-enriched eggs

Researchers investigated the effect of a diet of selenium- and/or zinc-enriched eggs (SZE) on oxidative stress, cognitive impairment, and intestinal flora in D-galactose-induced aging mice.

15 Feb 2024

Combo of targeted and immunotherapy may boost NSCLC treatment by overcoming immune resistance and enhancing anti-tumor activity

Researchers evaluated rational combination treatment regimens for advanced/metastatic non-small-cell lung cancer (NSCLC).

15 Feb 2024

Mussel oil beats fish oil in atherosclerosis prevention, animal study finds

A study in "Frontiers in Nutrition" shows mussel oil significantly outperforms fish oil in preventing atherosclerosis in mice, suggesting a potential superior dietary supplement for human cardiovascular health.

14 Feb 2024

Groundbreaking model predicts heart attack risk months in advance

Study introduces a novel biomarker-based model to predict imminent myocardial infarction (IMI), identifying key proteins and metabolites that could revolutionize early detection and prevention strategies.

14 Feb 2024