Stem Cells News and Research

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Stem cells have the remarkable potential to develop into many different cell types in the body during early life and growth. In addition, in many tissues they serve as a sort of internal repair system, dividing essentially without limit to replenish other cells as long as the person or animal is still alive. When a stem cell divides, each new cell has the potential either to remain a stem cell or become another type of cell with a more specialized function, such as a muscle cell, a red blood cell, or a brain cell.

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

As people get older so do the hematopoietic stem cells (HSCs) that form their blood, creating an increased risk for compromised immunity and certain blood cancers. Now researchers are reporting in the scientific journal that the bone marrow niche where HSC's form also ages, contributing to the problem.

3 Mar 2017

Researcher examines scarring process in hope of preventing chronic lung transplant rejection

For patients affected by lung diseases such as pulmonary fibrosis, chronic obstructive pulmonary disease, cystic fibrosis and others, cures for their diseases are incredibly rare, if not nonexistent.

2 Mar 2017

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

A team led by Pr. Marina Cavazzana conducted at Necker Children's Hospital, AP-HP and the Imagine Institute in October 2014 gene therapy in the context of a phase I clinical trial / II in a patient 13 years with severe sickle cell disease.

2 Mar 2017

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Chemotherapy treatment targets and kills cancer cells in the body. However, even after treatment, some cancer cells may remain in the patient's system undetected.

2 Mar 2017

Study identifies potential therapeutic target for bone repair in adults with severe injury or disease

Irish scientists are developing an advanced technology to speed up bone repair in adults who have suffered severe fractures and bone degeneration.

1 Mar 2017

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

University of North Carolina Lineberger Comprehensive Cancer Center researchers have achieved a major milestone with the launch of two clinical trials testing an experimental therapy in which patients' own immune cells are genetically engineered to fight their cancer.

1 Mar 2017

Scientists develop in vitro stem cell-based bioassay for detecting biological activity of BoNTs

Scientists at the Institute for Infectious Diseases, University of Bern have developed an in vitro stem cell-based bioassay grown on multi-electrode arrays capable of detecting the biological activity of Clostridium botulinum neurotoxins.

28 Feb 2017

Stem cells strictly abide by innate developmental clocks, study shows

The mystery of what controls the range of developmental clocks in mammals — from 22 months for an elephant to 12 days for an opossum — may lie in the strict time-keeping of pluripotent stem cells for each unique species.

28 Feb 2017

Scientists gain new insight into early brain pathology of schizophrenia using adult skin cells

The skin cells of four adults with schizophrenia have provided an unprecedented "window" into how the disease began while they were still in the womb, according to a recent paper in Schizophrenia Research.

27 Feb 2017

Fat stem cells may be preferred type for use in therapeutic applications, study shows

An international team of researchers, funded by Morris Animal Foundation, has shown that adipose (fat) stem cells might be the preferred stem cell type for use in canine therapeutic applications, including orthopedic diseases and injury.

27 Feb 2017

Study finding suggests new ways in which genetic mutations may cause brain disorders

Many kids say they love their mom and dad equally, but there are times when even the best prefers one parent over the other. The same can be said for how the body's cells treat our DNA instructions. It has long been thought that each copy - one inherited from mom and one from dad - is treated the same. A new study from scientists at the University of Utah School of Medicine shows that it is not uncommon for cells in the brain to preferentially activate one copy over the other.

25 Feb 2017

Novel antiviral drug can protect transplant patients against CMV infections

In a significant advance in improving the safety of donor stem cell transplants, a major clinical trial led by researchers at Dana-Farber Cancer Institute and Brigham and Women's Hospital has shown that a novel agent can protect against the most common viral infection that patients face after transplantation.

24 Feb 2017

New humanized model enables better characterization of Alzheimer's pathology

Cells behave differently when removed from their environments, just as cells that develop in cultures do not behave like cells in living creatures.

24 Feb 2017

Study shows how old blood stem cells can be rejuvenated

When we are young, our blood stem cells produce an even and well-balanced number of red and white blood cells according to need. As we age, however, the capacity of the blood stem cells to produce the number of blood cells we need declines.

24 Feb 2017

Research: Biomaterials that mimic bone marrow can alter blood cell development

Researchers at the University of Illinois report they can alter blood cell development through the use of biomaterials designed to mimic characteristics of the bone marrow.

23 Feb 2017

Sanford scientists focus on utility of adult-derived stem cells

Sanford Research scientists recently published a review article in an issue of Stem Cells Translational Medicine focused on the study of and utility of adult-derived stem cells.

22 Feb 2017

Study finds biochemical pathway that triggers regrowth of breast cancer stem cells after chemotherapy

Working with human breast cancer cells and mice, researchers at Johns Hopkins say they have identified a biochemical pathway that triggers the regrowth of breast cancer stem cells after chemotherapy.

22 Feb 2017

Epigenetic changes that affect formation of new muscle cells may be contributing factor to obesity

Obesity is associated with reduced muscle mass and impaired metabolism. Epigenetic changes that affect the formation of new muscle cells may be a contributing factor, according to new research from Lund University, Sweden.

22 Feb 2017

Essen Bioscience to Showcase IncuCyte® Live-cell Analysis System and Applications at AACR, Booth #1365

The IncuCyte® live-cell analysis platform from Essen BioScience will be showcased at the upcoming AACR conference, booth #1365.

From Sartorius 22 Feb 2017

Treating multiple myeloma with rabbit virus eliminates majority of malignant cells, study shows

Treating multiple myeloma (MM) with myxoma virus (MYXV) eliminated a majority of malignant cells in preclinical studies, report investigators at the Medical University of South Carolina and elsewhere in an article published online on December 7, 2016 by Molecular Therapy -- Oncolytics.

22 Feb 2017

Stem Cells News and Research

Further Reading

Scientists propose rejuvenating bone marrow stem cell niche to boost immunity, fend off cancers

Researcher examines scarring process in hope of preventing chronic lung transplant rejection

Innovative gene therapy allows complete remission of clinical signs of sickle cell disease

Researchers looking at ways to target lingering cancer stem cells that cause disease relapse

Study identifies potential therapeutic target for bone repair in adults with severe injury or disease

UNC Lineberger achieves major milestone with launch of cellular immunotherapy program

Scientists develop in vitro stem cell-based bioassay for detecting biological activity of BoNTs

Stem cells strictly abide by innate developmental clocks, study shows

Scientists gain new insight into early brain pathology of schizophrenia using adult skin cells

Fat stem cells may be preferred type for use in therapeutic applications, study shows

Study finding suggests new ways in which genetic mutations may cause brain disorders

Novel antiviral drug can protect transplant patients against CMV infections

New humanized model enables better characterization of Alzheimer's pathology

Study shows how old blood stem cells can be rejuvenated

Research: Biomaterials that mimic bone marrow can alter blood cell development

Sanford scientists focus on utility of adult-derived stem cells

Study finds biochemical pathway that triggers regrowth of breast cancer stem cells after chemotherapy

Epigenetic changes that affect formation of new muscle cells may be contributing factor to obesity

Essen Bioscience to Showcase IncuCyte® Live-cell Analysis System and Applications at AACR, Booth #1365

Treating multiple myeloma with rabbit virus eliminates majority of malignant cells, study shows

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