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Antidepressants induce new nerve cell growth in the hippocampus

The growth of new nerve cells in the hippocampus has been suggested as the way antidepressants work in rodents, says Eric Nestler, MD, PhD, of the University of Texas Southwestern Medical Center.

8 May 2007

New way to target and potentially treat tumors

Research teams at Yale University and the University of Rhode Island have demonstrated a new way to target and potentially treat tumors using a short piece of protein that acts like a nanosyringe to deliver tags or therapy to cells, according to a report in the Proceedings of the National Academy of Sciences.

2 May 2007

Phenoxodiol, an investigational drug shows promise for ovarian cancer

A new study further supports the unique mechanism of action of phenoxodiol, an investigational drug being studied for the treatment of ovarian cancer.

2 May 2007

Cancer Research Technology licenses therapeutic antibodies to Peptech

Cancer Research Technology Limited (CRT), the oncology-focused development and commercialisation company, today announces it has licensed rights to a panel of cancer therapeutic antibodies to Peptech Limited.

2 May 2007

Smelling for first time results from knowing abnormalities in congenital loss of smell

New discoveries about the biochemical basis of the majority of cases of the congenital inability to smell any odor, no matter how strong, have enabled their discoverer, Dr. Robert I. Henkin, director of The Taste and Smell Clinic in Washington, DC, to treat such patients, enabling them to smell something for the first time in their lives.

1 May 2007

New mechanism identified for resistance to targeted lung cancer drugs

An international research team, led by investigators from the Massachusetts General Hospital (MGH) Cancer Center and Dana-Farber Cancer Institute (DFCI), has found a new way that some lung tumors become resistant to treatment with targeted therapy drugs like Iressa and Tarceva.

27 Apr 2007

Johns Hopkins team stops form of blood cancer in its tracks

A Johns Hopkins team has stopped in its tracks a form of blood cancer in mice by engineering and inactivating an enzyme, telomerase, thereby shortening the ends of chromosomes, called telomeres.

26 Apr 2007

Surprising new theory on antibiotic resistance

A surprising new theory developed at the University of Nebraska Medical Center (UNMC) in Omaha, Nebraska, suggests that some bacterial cells act as "suicide bombers" in cell communities, with the altruistic intention of dying for the common good - and in the process, strengthening other cells that then become resistant to antibiotic drugs.

25 Apr 2007

Mode of action of EpiCept-licensed cancer compound profiled at AACR

EpiCept Corporation has reported that studies characterizing a dual mode of action for Azixa, a compound licensed by the Company to Myriad Genetics, Inc.

24 Apr 2007

Miscue of body's genetic repair system may cause Huntington's disease

Mayo Clinic researchers, along with collaborators from the National Institutes of Health (NIH) and University of Oslo, Norway, have discovered that a miscue of the body's genetic repair system may cause Huntington's disease, a fatal condition that affects 30,000 Americans annually by destroying their nervous system.

24 Apr 2007

Pharmacyclics announces NDA for Xcytrin injection

Pharmacyclics, Inc. has announced that the U.S. Food and Drug Administration (FDA) has filed the company's New Drug Application (NDA) for Xcytrin (motexafin gadolinium) Injection.

24 Apr 2007

Naturally occurring compound found in many fruits and vegetables as well as red wine, selectively kills leukemia cells

These findings, which were published online March 20 in the Journal of Biological Chemistry and will be in press on May 4, offer hope for a more selective, less toxic therapy for leukemia.

24 Apr 2007

Novel targeted therapy effectively treats acute leukemia

Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found that a novel targeted therapy effectively treats acute leukemia in animal models by preventing cancer cells from being purged of damaged proteins.

20 Apr 2007

New research may help identify patients most likely to benefit from cisplatin treatment

Researchers at the Massachusetts General Hospital (MGH) Cancer Center have identified a subgroup of hard-to-treat breast cancers that may be sensitive to the drug cisplatin, rarely used in the treatment of breast tumors.

20 Apr 2007

Green tea may help protect against Sjogren's syndrome

They found significantly less salivary gland damage in a group treated with green tea extract, suggesting a reduction of the Sjogren's symptom commonly referred to as dry mouth. Dry mouth can also be caused by certain drugs, radiation and other diseases.

20 Apr 2007