Clinical Trial News and Research

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Researchers develop a mathematical model to predict COVID-19 vaccine efficacy

Researchers at The University of Queensland have developed a mathematical model that can predict the efficacy of COVID-19 vaccines, potentially speeding-up the development of new vaccines.

14 Mar 2022

New Phase 1 clinical trial of mRNA HIV vaccine enrolls first participant

The first 12 study participants have been enrolled in a new Phase 1 clinical trial using the messenger ribonucleic acid (mRNA) vaccine technology developed by Moderna.

14 Mar 2022

Malaria drug could help treat chemotherapy-resistant head and neck cancers

A new study suggests that the malaria drug hydroxychloroquine inhibits pathways that drive resistance to the chemotherapy agent cisplatin in head and neck cancers and restores tumor-killing effects of cisplatin in animal models.

14 Mar 2022

NIH launches Phase 1 clinical trial evaluating three experimental mRNA HIV vaccines

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has launched a Phase 1 clinical trial evaluating three experimental HIV vaccines based on a messenger RNA (mRNA) platform—a technology used in several approved COVID-19 vaccines.

14 Mar 2022

Study evaluates efficacy of isotretinoin in improving COVID-19 outcomes

Researchers evaluated the effectiveness of isotretinoin (13-cis retinoic acid) in improving COVID-19 outcomes.

14 Mar 2022

The impact of PLEX on the survival of patients with severe COVID-19 and the effect on the cytokine release syndrome

Researchers evaluated the survival benefit conferred by PLEX in patients with severe COVID-19 and cytokine-storm syndrome.

14 Mar 2022

Cellular therapy offers promise for patients with Duchenne muscular dystrophy, trial shows

A clinical trial at UC Davis Health and six other sites showed that a cellular therapy offers promise for patients with late-stage Duchenne muscular dystrophy (DMD), a rare genetic disorder causing muscle loss and physical impairments in young people.

10 Mar 2022

Damage to the inner ear system linked to fall risk among Alzheimer’s patients

A Johns Hopkins Medicine study of about 50 people with Alzheimer's disease has added to evidence that damage to the inner ear system that controls balance is a major factor in patients' well-documented higher risk of falling.

10 Mar 2022

Shorter treatment for children with non-severe tuberculosis

A UCL-led international trial exploring the effectiveness of tuberculosis (TB) treatment in children has led to a change in the World Health Organisation's global guidelines for managing the disease.

10 Mar 2022

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

The new drug nirsevimab showed 74.5 percent efficacy against medically attended lower respiratory tract infections caused by respiratory syncytial virus (RSV) in healthy infants, according to an international, randomized, placebo-controlled phase 3 clinical trial published in the New England Journal of Medicine.

9 Mar 2022

Clinical trial of novel rabies vaccine in human volunteers begins in Tanzania

The University of Oxford and the Ifakara Health Institute today announced the vaccination of the first participants in a Phase Ib/II trial testing a novel rabies vaccine in human volunteers in Tanzania.

9 Mar 2022

Mathematical model for evaluating factors driving SARS-CoV-2 transmission and pathogenesis

A new study provides an overview of the use of mathematical modeling to determine severe acute respiratory syndrome coronavirus 2 kinetics.

9 Mar 2022

Self-administered screening on a tablet device may improve the detection of at-risk patients

Have you ever felt uncomfortable when asked about depression or any other sensitive personal issue when checking in for a medical visit?

8 Mar 2022

AI-ECG algorithms can enhance detection and treatment of hypertrophic cardiomyopathy

Hypertrophic cardiomyopathy (HCM) is a leading cause of sudden death in adolescents and initial detection is often difficult.

8 Mar 2022

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

A recent study predicted the efficacy of the SOBERANA 02 and SOBERANA Plus COVID-19 vaccines in children.

8 Mar 2022

Study offers insight into molecular biology of the brain in bipolar disorder patients

In a comprehensive study involving one of the largest-ever samples of post-mortem brains, scientists at the Lieber Institute for Brain Development, in collaboration with researchers at the Johns Hopkins School of Medicine and Bloomberg School of Public Health, have pinpointed significant differences in gene expression in two specific regions of the brains of hundreds of patients who had bipolar disorder.

7 Mar 2022

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

Many people aspire to live longer, healthier lives. A researcher at Baylor College of Medicine, Dr. Rajagopal Sekhar, associate professor of medicine in the section of endocrinology, diabetes and metabolism, has been studying aging for the past 20 years to better understand its biological underpinnings and develop nutritional strategies to promote healthy aging.

7 Mar 2022

Clinical Trial News and Research

Researchers develop a mathematical model to predict COVID-19 vaccine efficacy

New Phase 1 clinical trial of mRNA HIV vaccine enrolls first participant

Malaria drug could help treat chemotherapy-resistant head and neck cancers

NIH launches Phase 1 clinical trial evaluating three experimental mRNA HIV vaccines

Study evaluates efficacy of isotretinoin in improving COVID-19 outcomes

The impact of PLEX on the survival of patients with severe COVID-19 and the effect on the cytokine release syndrome

Cellular therapy offers promise for patients with Duchenne muscular dystrophy, trial shows

Damage to the inner ear system linked to fall risk among Alzheimer’s patients

Shorter treatment for children with non-severe tuberculosis

Single dose of new drug nirsevimab provides safe protection against RSV in healthy infants

Clinical trial of novel rabies vaccine in human volunteers begins in Tanzania

Mathematical model for evaluating factors driving SARS-CoV-2 transmission and pathogenesis

Self-administered screening on a tablet device may improve the detection of at-risk patients

AI-ECG algorithms can enhance detection and treatment of hypertrophic cardiomyopathy

Study evaluates heterologous vaccination scheme in children using two SARS-CoV-2 RBD protein vaccines

Study offers insight into molecular biology of the brain in bipolar disorder patients

GlyNAC supplementation can increase lifespan and improve multiple age-associated defects

New treatment strategy makes pancreatic tumors sensitive to immunotherapy, mice study shows

Study finds increased risk of early death for survivors of heart attack plus cardiac arrest

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