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Dramatically enhanced image contrast could revolutionize diagnostics and therapeutics

A Northwestern University study shows that coupling a magnetic resonance imaging (MRI) contrast agent to a nanodiamond results in dramatically enhanced signal intensity and thus vivid image contrast.

18 Jan 2010

Obama signals interest in reducing the protections for biologic drugs

Lobbyists for generic biologic drugmakers are fighting to undercut a provision in the proposed health overhaul that would protect brand-name pharmaceutical companies from lower-cost, generic competition over new products for 12 years, the Associated Press reports. The generic companies have friends in high places: "White House officials and Rep. Henry Waxman, D-Calif., chairman of the House Energy and Commerce Committee, are trying to reduce the curbs against competition to 10 years or less" (Fram, 1/14).

18 Jan 2010

FDA: Data from Spiriva HandiHaler do not support increased risks for stroke, heart attack or death

The U.S. Food and Drug Administration today announced that data from a recent review of the Spiriva HandiHaler, a long-acting respiratory treatment for chronic obstructive pulmonary disease (COPD), do not support an increased risk of stroke, heart attack, or death in patients using the medicine.

18 Jan 2010

Research reveals gene activation is linked to most aggressive type of brain cancer

Glioblastoma (GBM), the brain cancer better known for having killed Senator Ted Kennedy a few months ago, is the most aggressive and lethal of all brain tumours.

18 Jan 2010

Health care fraud is big business

Health care fraud has become a multi-billion dollar industry - up to $100 billion a year, according to estimates - for scammers and organized crime gangs, CNNMoney reports. In recent months health care identity theft has topped the list of crimes, a con in which criminals to tap real patient information to rack up fake charges.

18 Jan 2010

Fertility drugs cause a high percentage of multiple births; contribute to growing crisis of prematurity

The widespread use of so-called fertility drugs, not just high-tech laboratory procedures, likely plays a larger role than previously realized in the growing problem of premature births in the United States, because these drugs cause a high percentage of multiple births, the March of Dimes said today.

18 Jan 2010

Atlantic examines drug-resistant TB control worldwide

The Atlantic examines the emergence of drug-resistant strains of tuberculosis around the world, with a look at the situation in South Africa. "[T]he resurgence of tuberculosis is not limited to South Africa. India and China have the largest numbers of tuberculosis cases, and multi-drug-resistant tuberculosis (MDR-TB) has been found in nearly every country, with XDR [extensively drug resistant]-TB in at least 57 countries," according to the article.

18 Jan 2010

Safety concerns of acetaminophen

The pain reliever acetaminophen is one of the safest and most effective drugs on the market. It's often recommended instead of aspirin as a day-to-day pain reliever because it's much easier on the stomach than other over-the-counter options and is considered safe when taken properly.

18 Jan 2010

OSA adversely affects glucose control in patients with type 2 diabetes

Obstructive Sleep Apnea (OSA) adversely affects glucose control in patients with type 2 diabetes, according to a study conducted by researchers at the University of Chicago.

18 Jan 2010

Three proteins that lead to memory loss associated with Alzheimer's disease identified

A scientific group led by the Translational Genomics Research Institute (TGen) have identified three kinases, or proteins, that dismantle connections within brain cells, which may lead to memory loss associated with Alzheimer's disease.

18 Jan 2010

Democrats reportedly settle key issues on health bill but no final accord yet

Politico reports: "President Barack Obama and senior Democratic lawmakers closed in Friday on a final health care reform package, finishing a week of intensive negotiations on tax and coverage issues that had once threatened to derail the bill.

18 Jan 2010

Longer breastfeeding can prevent postnatal HIV transmission

A new study from Zambia suggests that halting breastfeeding early causes more harm than good for children not infected with HIV who are born to HIV-positive mothers.

18 Jan 2010

Kenta Biotech and Rentschler Biotechnologie sign agreement to develop antibody against MRSA

Kenta Biotech today announced an agreement with Rentschler Biotechnologie for the development of a fully human monoclonal antibody against methicillin-resistant Staphylococcus aureus (MRSA).

18 Jan 2010

FTC wants to ban 'pay-to-delay' settlements related to generic drugs

The Associated Press/USA Today: "The Federal Trade Commission says patent settlements between drugmakers that cost U.S. consumers billions each year are on the rise. The agency reported Wednesday that the number of lucrative settlements between brand-name and generic drug companies rose to 19 last year from 16 in 2008 and 14 the year before."

18 Jan 2010

IGC scientist wins ERC grant for neuroscience research

Zachary Mainen, coordinator of the Champalimaud Foundation Neuroscience Programme at the IGC, has become one of the most recent winners of the prestigious and highly competitive European Research Council grants, to the value of 2.3 million euro, for a period of five years.

18 Jan 2010

M. D. Anderson researchers discover mechanism that helps glioblastomas evade immune attack

Cancer-initiating cells that launch glioblastoma multiforme, the most lethal type of brain tumor, also suppress an immune system attack on the disease, scientists from The University of Texas M. D. Anderson Cancer Center report in a paper featured on the cover of the Jan. 15 issue of Clinical Cancer Research.

18 Jan 2010

First genetic map of malaria drug plant could increase crop yields, study says

The first genetic map of the plant Artemisia annua, which could "help scientists develop the species into a high-yielding crop" to fight malaria, was published in a study in the journal Science on Thursday, Reuters reports (Kelland, 1/14).

18 Jan 2010

Treatment for chronic hepatitis C with pegylated-interferon and ribavirin proves effective

The current standard treatment for chronic hepatitis C with pegylated-interferon (PEG-IFN) and ribavirin is effective in approximately 50%-60% of patients, so that a substantial proportion of patients remain unresponsive.

18 Jan 2010

New class of drugs could help prevent skin cancer

A new study by Loyola University Health System researchers could lead to alternative treatments that would shrink skin cancer tumors with drugs. The drugs would work by turning on a gene that prevents skin cells from becoming cancerous, said senior author Mitchell Denning, Ph.D.

18 Jan 2010

Study raises concerns about drug-resistant HIV

The emergence of drug-resistant strains of HIV could one day threaten efforts to control the global HIV pandemic, according to a study published online Thursday in the journal Science, HealthDay News/U.S. News & World Report reports. The researchers based their findings on "a mathematical model that tracks the transmission of multiple strains of HIV" in San Francisco, the news service writes (1/14).

18 Jan 2010

Drugs News and Research

Dramatically enhanced image contrast could revolutionize diagnostics and therapeutics

Obama signals interest in reducing the protections for biologic drugs

FDA: Data from Spiriva HandiHaler do not support increased risks for stroke, heart attack or death

Research reveals gene activation is linked to most aggressive type of brain cancer

Health care fraud is big business

Fertility drugs cause a high percentage of multiple births; contribute to growing crisis of prematurity

Atlantic examines drug-resistant TB control worldwide

Safety concerns of acetaminophen

OSA adversely affects glucose control in patients with type 2 diabetes

Three proteins that lead to memory loss associated with Alzheimer's disease identified

Democrats reportedly settle key issues on health bill but no final accord yet

Longer breastfeeding can prevent postnatal HIV transmission

Kenta Biotech and Rentschler Biotechnologie sign agreement to develop antibody against MRSA

FTC wants to ban 'pay-to-delay' settlements related to generic drugs

IGC scientist wins ERC grant for neuroscience research

M. D. Anderson researchers discover mechanism that helps glioblastomas evade immune attack

First genetic map of malaria drug plant could increase crop yields, study says

Treatment for chronic hepatitis C with pegylated-interferon and ribavirin proves effective

New class of drugs could help prevent skin cancer

Study raises concerns about drug-resistant HIV

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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