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Study unveils potential treatment for chronic brain damage following traumatic injury

Violent blows or jolts to the head can cause traumatic brain injury (TBI), and there are currently about five million people in the U.S. living with chronic neurodegeneration and related impairments due to TBI.

11 Sep 2024

Taletrectinib shows high response rates and safety in ROS1+ lung cancer patients

The ROS1 tyrosine kinase inhibitor (TKI) taletrectinib demonstrated high overall and intracranial responses, and a favorable safety profile with low incidence of neurologic adverse events in TKI-naive and TKI-pretreated patients with ROS1+ non-small cell lung cancer (NSCLC).

11 Sep 2024

Pre-surgery chemotherapy shows promise for preserving vital organs in nasal and sinus cancer

Results from a clinical trial by the ECOG-ACRIN Cancer Research Group (ECOG-ACRIN) show a striking improvement for patients who received chemotherapy before surgery to remove advanced squamous cell-type cancer of the nose or sinus.

11 Sep 2024

VitelloTag approach offers new solution for gene editing challenges in egg cells

A new approach for delivering miniature research tools into the interior of egg cells and embryos has been developed at the Marine Biological Laboratory (MBL), resolving a major bottleneck to using the gene-editing tool CRISPR-Cas9 in many research organisms.

11 Sep 2024

Study unveils dynamic brain architecture through advanced fMRI techniques Neuroscientists In Spain ...

Researchers from the Institute for Neurosciences (IN), a joint center of the Spanish National Research Council (CSIC) and the Miguel Hernández University (UMH) of Elche, along with a team from the Transylvanian Institute of Neuroscience (Romania), and in collaboration with experts from the Universitat Politècnica de València, have developed an innovative approach to studying brain connections using functional magnetic resonance imaging (fMRI).

11 Sep 2024

Innovative method unlocks potential for drugging undruggable GTPases

Drugs for the K-Ras oncogene inspire an approach for targeting the GTPases, a family of enzymes whose dysfunction can lead to Parkinson's and many other diseases.

11 Sep 2024

Disrupted glucose transport in oligodendrocytes linked to myelin thinning and aging in new research

This study uncovers how oligodendroglial lipid metabolism supports myelin homeostasis and axonal function under metabolic stress, crucial for neurodegeneration.

11 Sep 2024

A promising new therapeutic target for MASLD identified

Using a novel stem cell platform, a team of the Medical University of South Carolina researchers has identified a pathway that could be targeted by drugs to reduce fat accumulation in patients with a common form of fatty liver disease known as metabolic dysfunction-associated steatotic liver disease, or MASLD.

11 Sep 2024

Promising new approach to combat HIV

Researchers at Université de Montréal's affiliated hospital research center, the CRCHUM, say the discovery could help lessen and even eliminate viral loads in people undergoing antiretroviral therapy.

11 Sep 2024

Fibrous scars drive glioblastoma recurrence

A Ludwig Cancer Research study has discovered that recurrent tumors of the aggressive brain cancer glioblastoma multiforme (GBM) grow out of the fibrous scars of malignant predecessors destroyed by interventions such as radiotherapy, surgery, and immunotherapy.

11 Sep 2024

New target identified for potential ALS therapy

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease that affects motor neurons.

10 Sep 2024

Girls exposed to endocrine-disrupting chemicals may be more likely to start puberty early

Girls exposed to certain endocrine-disrupting chemicals (EDCs) may be more likely to start puberty early, according to new research published in Endocrinology, the flagship basic science journal of the Endocrine Society.

10 Sep 2024

New AI model creates virtual colorations of cancer tissue for enhanced diagnostics

A recent study published in Nature Machine Intelligence introduces an advanced artificial intelligence (AI) model capable of creating virtual colorations of cancer tissue.

10 Sep 2024

U-M study reveals how propofol affects brain connectivity and consciousness

In hospital operating rooms and intensive care units, propofol is a drug of choice, widely used to sedate patients for their comfort or render them fully unconscious for invasive procedures.

10 Sep 2024

By-products from olive oil production show promise for preventing cardiovascular disease, study shows

A study reveals olive oil wastewater extract enriched with hydroxytyrosol shows promise in preventing cardiovascular diseases through antioxidant properties.

10 Sep 2024

High linoleic acid intake during pregnancy may harm fetal growth and raise obesity risk

High maternal linoleic acid intake during pregnancy may impact fetal development and increase the risk of obesity and inflammation in offspring. However, more research is needed to fully understand these effects in humans.

10 Sep 2024

SP-101 gene therapy shows promise for cystic fibrosis treatment

Scientists from Spirovant Sciences describe SP-101, a novel adeno-associated virus (AAV) gene therapy for the treatment of cystic fibrosis (CF) in the peer-reviewed journal Human Gene Therapy.

9 Sep 2024

GLP-1 receptor agonists show promise in treating substance use disorders

A systematic review reveals that GLP-1 receptor agonists may help reduce certain substance use disorders, but findings are inconsistent due to study variability and patient differences.

9 Sep 2024

Cell-free RNA analysis enhances early detection of pediatric inflammatory conditions

RNA is expelled from cells via cell death or active release, and can then find its way into blood plasma. A Cornell University-led collaboration has developed machine learning models that use these cell-free molecular RNA dregs to diagnose pediatric inflammatory conditions that are difficult to differentiate.

9 Sep 2024

Researchers uncover mechanism fueling prostate cancer

Researchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason why a typically normal protein goes awry and fuels cancer.

9 Sep 2024

B Cell News and Research

Study unveils potential treatment for chronic brain damage following traumatic injury

Taletrectinib shows high response rates and safety in ROS1+ lung cancer patients

Pre-surgery chemotherapy shows promise for preserving vital organs in nasal and sinus cancer

VitelloTag approach offers new solution for gene editing challenges in egg cells

Study unveils dynamic brain architecture through advanced fMRI techniques Neuroscientists In Spain ...

Innovative method unlocks potential for drugging undruggable GTPases

Disrupted glucose transport in oligodendrocytes linked to myelin thinning and aging in new research

A promising new therapeutic target for MASLD identified

Promising new approach to combat HIV

Fibrous scars drive glioblastoma recurrence

New target identified for potential ALS therapy

Girls exposed to endocrine-disrupting chemicals may be more likely to start puberty early

New AI model creates virtual colorations of cancer tissue for enhanced diagnostics

U-M study reveals how propofol affects brain connectivity and consciousness

By-products from olive oil production show promise for preventing cardiovascular disease, study shows

High linoleic acid intake during pregnancy may harm fetal growth and raise obesity risk

SP-101 gene therapy shows promise for cystic fibrosis treatment

GLP-1 receptor agonists show promise in treating substance use disorders

Cell-free RNA analysis enhances early detection of pediatric inflammatory conditions

Researchers uncover mechanism fueling prostate cancer

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