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Cancer cells exploit genetic and cellular processes to promote tumor growth

Writing in EMBO reports, researchers at University of California San Diego School of Medicine and Moores Cancer Center at UC San Diego Health describe how a pair of fundamental genetic and cellular processes are exploited by cancer cells to promote tumor survival and growth.

29 Oct 2021

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

A decade ago, genome sequencing revealed a big surprise: about 50 percent of human cancers are linked to mutations in what are known as epigenetic regulators, which control the activity of genes.

29 Oct 2021

Researchers develop eToeholds for safe, effective RNA and cellular therapies

RNAs are best known as the molecules that translate information encoded in genes into proteins with their myriad of activities.

29 Oct 2021

The role of CRISPR in viral diagnostics

A comprehensive review explains in depth how CRISPR can be utilized as a reliable tool to investigate the viral life cycles.

29 Oct 2021

Scientists uncover key genetic networks governing human embryonic stem cell behavior

At the earliest stages of human embryonic development, a small collection of cells known as human embryonic stem cells (hESCs) orchestrates growth and differentiation, eventually giving rise to highly specialized human tissues.

28 Oct 2021

Penn's newly created split-engineered base editors show potential for research, therapeutics

Targeted mutations to the genome can now be introduced by splitting specific mutator enzymes and then triggering them to reconstitute, according to research from the Perelman School of Medicine at the University of Pennsylvania.

28 Oct 2021

Study unravels how cells protect against influenza A viruses

Human cells use a protein named TBC1D5 to route influenza A viruses inside host cells for destruction, preventing the virus from spreading replicated copies of itself to other cells, according to a study published in Nature Microbiology.

28 Oct 2021

How long does natural or vaccine-induced immunity to COVID last?

Researchers present a comprehensive assessment on SARS-CoV-2 induced immunity.

28 Oct 2021

New insight into the tremendously complex "genetic dance"

The rapid scientific advancements that followed the mapping of the human genome have revealed just how staggeringly complex the world of genetics is.

28 Oct 2021

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Researchers at the Francis Crick Institute, The Royal Marsden NHS Foundation Trust and UCL have found immune cell patterns within tumors that can help predict if patients with kidney cancer will respond to immunotherapy.

28 Oct 2021

Sphere Fluidics closes a $40 million funding round led by Sofinnova Partners and Redmile Group

Sphere Fluidics announced today that it has closed a $40 million (circa £30 million) investment round.

From Fluidic Sciences and Sphere Bio 28 Oct 2021

The difference in the dynamics of SARS-COV-2 variants

A new study provides a detailed description of the varying interactions between SARS-CoV-2 and the host cell ACE-2 receptor.

27 Oct 2021

A study on the SARS-CoV-2 B.1.620 lineage

In a recently published Nature Communications study, the authors describe the B.1.620 lineage discovered in Lithuania.

27 Oct 2021

bit.bio expands Board of Directors with appointment of entrepreneurs and Nobel Laureate

Today bit.bio welcomed three new members to its Board of Directors, who bring their respective experience of turning world-class science into new industries.

From bit.bio 27 Oct 2021

Lung cancer-associated fibroblasts could guide the design of personalized treatments

Three subtypes of cancer-associated fibroblasts (CAF) could guide the design of personalized treatment for lung cancer patients, according to a new study in Cancer Cell led by researchers at Massachusetts General Hospital.

26 Oct 2021

NIH invests $74.5 million to advance data science research and spur health discoveries across Africa

The National Institutes of Health is investing about $74.5 million over five years to advance data science, catalyze innovation and spur health discoveries across Africa.

26 Oct 2021

Mapping C. difficile: Advanced ribotyping technology helps researchers keep track of deadly disease

Interview with Seth Walk, Principal Investigator and Associate Professor, Department of Microbiology and Cell Biology, Montana State University

From Promega Corporation 26 Oct 2021

Water and surface surveillance can detect 93% of school-based COVID-19 cases

A new study posted to the medRxiv* preprint server explores environmental surveillance of elementary school settings for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) through wastewater and surface samples monitoring. The researchers demonstrated that 93% of the COVID-19 cases in public elementary schools could be identified using this method.

25 Oct 2021

N501Y mutation in SARS-CoV-2 Delta variant is key to breakthrough infections

A study in the Philadelphia area found that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants evolve to become more contagious and resistant to COVID-19 vaccines. In addition, depending on the sublineage, SARS-CoV-2 variants such as the Delta variant led to a three-fold increased risk for vaccine breakthrough cases.

25 Oct 2021

Study finds link between genes and amount of bacterial toxins in the blood

Lipopolysaccharide, a virulence factor produced by bacteria, is a toxin that can cause a systemic inflammation via the circulation. In a recently completed study, genetic markers were discovered which are associated with a heightened lipopolysaccharide level in the blood.

25 Oct 2021

Genome News and Research

Cancer cells exploit genetic and cellular processes to promote tumor growth

Drug-like molecule can counteract the effects of mutated epigenetic regulators that drive cancers

Researchers develop eToeholds for safe, effective RNA and cellular therapies

The role of CRISPR in viral diagnostics

Scientists uncover key genetic networks governing human embryonic stem cell behavior

Penn's newly created split-engineered base editors show potential for research, therapeutics

Study unravels how cells protect against influenza A viruses

How long does natural or vaccine-induced immunity to COVID last?

New insight into the tremendously complex "genetic dance"

Immune cell patterns can help predict if kidney cancer patients will respond to immunotherapy

Sphere Fluidics closes a $40 million funding round led by Sofinnova Partners and Redmile Group

The difference in the dynamics of SARS-COV-2 variants

A study on the SARS-CoV-2 B.1.620 lineage

bit.bio expands Board of Directors with appointment of entrepreneurs and Nobel Laureate

Lung cancer-associated fibroblasts could guide the design of personalized treatments

NIH invests $74.5 million to advance data science research and spur health discoveries across Africa

Mapping C. difficile: Advanced ribotyping technology helps researchers keep track of deadly disease

Water and surface surveillance can detect 93% of school-based COVID-19 cases

N501Y mutation in SARS-CoV-2 Delta variant is key to breakthrough infections

Study finds link between genes and amount of bacterial toxins in the blood

Genetics & Genomics - Second Edition eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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