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GLP-1 weight loss drugs linked to heightened GI risks, says new study

Study from JAMA reveals that users of GLP-1 agonists, recent drugs for weight management, show a heightened risk of gastrointestinal complications like intestinal obstruction, gastroparesis, and pancreatitis. Though these effects are rare, those considering these drugs for weight loss should weigh the benefits against potential risks, especially if not using them for diabetes.

5 Oct 2023

'Guard mechanism' discovered for protein that attacks microbes in infected cells

Researchers have identified a 'guard mechanism' for a protein which attacks microbes in infected cells, opening the possibility of new treatments for Toxoplasma, Chlamydia, Tuberculosis and even cancer.

5 Oct 2023

Organoid medicine reveals promising covid-19 treatment target

When the new SARS-CoV-2 virus began killing thousands of people every week, physicians and scientists around the globe raced to learn why the new pathogen was so deadly.

5 Oct 2023

GLP-1 agonists linked to higher risk for gastrointestinal complications

They're being hailed as an effective way to lose weight, but diabetes drugs like Ozempic may come with a heightened risk of severe gastrointestinal problems.

5 Oct 2023

The metabolic effects of endocrine therapy on diabetes mellitus in breast cancer survivors

Researchers discuss the history of endocrine therapies, highlights their adverse metabolic effects, and emphasizes the need for better biomarkers of diabetes.

5 Oct 2023

Remote ischemic conditioning for acute stroke

The effect of remote ischemic conditioning (RIC) on functional outcomes in patients with acute stroke.

5 Oct 2023

Australia's Long COVID response falling behind global standards, research finds

New research by RMIT University and Northern Health has examined Australia's Long COVID services, guidelines and public health information, compared with international standards.

4 Oct 2023

Organ-on-chip model sheds light on lymphedema

In a new PNAS study co-authored by Boston University biomedical engineer Dr. Chris Chen, researchers say they're getting closer to understanding the mysteries of lymphedema - a condition characterized by the buildup of fluid in the body due to a malfunctioning lymphatic system.

4 Oct 2023

Study finds cluster of common conditions may signal early onset of type 2 diabetes

New research presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Hamburg (2-6 Oct), reveals a marked increase in several common conditions in the years leading up to, and immediately prior to, type 2 diabetes diagnosis, suggesting considerably earlier diagnosis might be possible in some patients.

4 Oct 2023

Oral lipid nanoparticle drug shows promise for preventing colitis-associated cancer in mice

An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by researchers in the Institute for Biomedical Sciences at Georgia State University.

4 Oct 2023

Effectiveness of Lactobacillus in treating inflammatory bowel disease

The role of Lactobacillus in treating inflammatory bowel disease.

4 Oct 2023

Sanofi and Teva announce exclusive collaboration to deliver inflammatory bowel disease treatment

Sanofi (EURONEXT: SAN and NASDAQ: SNY) and Teva Pharmaceuticals, a U.S. subsidiary of Teva Pharmaceutical Industries Ltd. (NYSE and TASE: TEVA) announce today a collaboration to co-develop and co-commercialize asset TEV’574, currently in Phase 2b clinical trials for the treatment of Ulcerative Colitis and Crohn's Disease, two types of inflammatory bowel disease.

From Sanofi 4 Oct 2023

Wood cookstove use linked to gastric cancer risk

Researchers conducted a population-based study with a case–control design in rural areas of Honduras in Central America to examine whether wood cookstove use by indigenous populations was associated with increased risk of stomach cancers, including gastric adenocarcinoma.

4 Oct 2023

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Researchers investigated endotype-phenotype associations in atopic dermatitis (AD) beyond its general clinical severity.

4 Oct 2023

Prioritising Lung Health: How FeNO can help to tackle Lung Conditions, the UK's 3rd Largest Threat

A new report from PwC commissioned by Asthma+Lung UK has highlighted the alarming crisis surrounding Lung Health in the UK.

From NObreath 4 Oct 2023

Walking and Mediterranean diet may be the ticket to reducing dementia risk

The study explores the MedWalk intervention, promoting a Mediterranean-style diet and regular walking, to potentially slow cognitive decline in older adults without existing impairments. Despite COVID-19 disruptions, progress with 157 participants suggests this approach, rooted in psychosocial techniques, could offer a lifestyle-based deterrent against dementia and cognitive deterioration.

4 Oct 2023

Could infants' robust immune responses reshape future vaccination strategies?

Utilizing next-gen sequencing techniques, researchers analyzed infants' immune responses to infections, uncovering a predominant innate immune activation unlike adults and older children. This insight could steer child vaccination research and pediatric infection management strategies, potentially revolutionizing infant healthcare.

3 Oct 2023

Inflammation News and Research

GLP-1 weight loss drugs linked to heightened GI risks, says new study

'Guard mechanism' discovered for protein that attacks microbes in infected cells

Organoid medicine reveals promising covid-19 treatment target

GLP-1 agonists linked to higher risk for gastrointestinal complications

The metabolic effects of endocrine therapy on diabetes mellitus in breast cancer survivors

Remote ischemic conditioning for acute stroke

Australia's Long COVID response falling behind global standards, research finds

Organ-on-chip model sheds light on lymphedema

Study finds cluster of common conditions may signal early onset of type 2 diabetes

Oral lipid nanoparticle drug shows promise for preventing colitis-associated cancer in mice

Effectiveness of Lactobacillus in treating inflammatory bowel disease

Sanofi and Teva announce exclusive collaboration to deliver inflammatory bowel disease treatment

Wood cookstove use linked to gastric cancer risk

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Prioritising Lung Health: How FeNO can help to tackle Lung Conditions, the UK's 3rd Largest Threat

Walking and Mediterranean diet may be the ticket to reducing dementia risk

Could infants' robust immune responses reshape future vaccination strategies?

New compound could offer an alternative to injections for people suffering from eye condition

Study identifies potential drug target for lymphedema

Microglial states and their impact on Alzheimer's disease

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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