Transplant News and Research

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SLU researchers examine health outcomes for obese transplant recipients

In a research review article published in the American Journal of Nephrology, Saint Louis University investigators examined data from multiple studies to better understand how obesity, an epidemic in the U.S., impacts kidney transplant patients.

16 Jan 2013

Over-expression of NEK2 in cancer cells significantly enhances drug resistance

Increased NEK2 gene expression linked to increased drug resistance, faster cancer growth, and poorer patient outcome - The finding may improved diagnostic and prognostic tools for cancer care and could lead to improved cancer therapies

16 Jan 2013

Donor liver wastage on the increase

US researchers have found that the expansion of liver transplantation criteria to include post-cardiac death donors is associated with an increase in the proportion of unused donor livers.

14 Jan 2013

Obesity complicates kidney transplantation

The risk for delayed graft function in patients undergoing kidney transplant rises in line with their body mass index, say US researchers.

14 Jan 2013

Angiotensin II blockade does not seem to provide benefit to kidney transplant recipients

A drug that protects the kidneys of patients with chronic kidney disease does not seem to provide the same benefit to kidney transplant recipients, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

11 Jan 2013

Lower liver quality from donation after cardiac death linked to drop in transplants

A new study, funded in part by the National Institutes of Health (NIH) and Health Resources and Services Administration, and published in the January 2013 issue of Liver Transplantation, a journal of the American Association for the Study of Liver Diseases (AASLD), found that the non-use of donor livers climbed through 2010 due to a worsening of donor liver quality, primarily from donation following cardiac death. Diabetes, donor age, and body mass index (BMI) were also linked to a decrease in use of organs.

11 Jan 2013

Apparent stem cell transplant success in mice may hold promise for people with ALS

Apparent stem cell transplant success in mice may hold promise for people with amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease.

11 Jan 2013

New publication focuses on microbiome research in environmental, agricultural and biomedical areas

Two prominent microbiologists have launched a new peer-reviewed publication focusing on microbiome research in environmental, agricultural, and biomedical areas. Eric Wommack, from the University of Delaware's College of Earth, Ocean and Environment and Jacques Ravel, from the University of Maryland School of Medicine's Institute for Genome Sciences are the Editors-in-Chief of Microbiome, a BioMed Central (BMC) publication, which launched its first issue this week.

9 Jan 2013

RPB honors Mass. Eye and Ear ophthalmologist with Senior Scientific Investigator Award

Reza Dana, M.D., M.P.H., M.Sc. of Mass. Eye and Ear/Harvard Medical School, was awarded the Research to Prevent Blindness (RPB) Senior Scientific Investigator Award in the amount of $150,000 to support research into the causes, treatment and prevention of blinding diseases.

9 Jan 2013

Thoratec to start REVIVE-IT study using HeartMate II Left Ventricular Assist System

Thoratec Corporation, a world leader in device-based mechanical circulatory support therapies to save, support and restore failing hearts, today announced that the U.S. Food and Drug Administration has granted an Investigational Device Exemption to commence the REVIVE-IT study utilizing the HeartMate II Left Ventricular Assist System.

8 Jan 2013

Markey practitioner receives Lexington Cancer Foundation grant to continue JSJ program

The University of Kentucky Markey Cancer Center's Jennifer Bradley has received funding from the Lexington Cancer Foundation to continue the Jin Shin Jyutsu program in 2013.

4 Jan 2013

Heart transplant patient becomes unexpected ambassador for organ donation

Kevin Riepl arrived at Cedars-Sinai in October 2010, suffering from sudden heart failure that left him fighting for his life. Surgeons swiftly installed a heart pump and later transplanted a new heart, saving his life and turning him into an unexpected ambassador for organ donation.

29 Dec 2012

Genome sequencing may help identify new targets to treat Pneumocystis pneumonia

Scientists have sequenced the genome of the fungus Pneumocystis jirovecii, an advancement that could help identify new targets for drugs to treat and prevent Pneumocystis pneumonia, a common and often deadly infection in immunocompromised patients.

26 Dec 2012

Real estate businessman delivers $2.5M gift to University of Chicago Medicine for GI study

Real estate businessman Seymour "Sy" Taxman and his wife, Nancy, presented a gift of $2.5 million to the University of Chicago Medicine on Wednesday in honor of the late Joseph B. Kirsner, MD, PhD, the Louis Block Distinguished Service Professor of Medicine and a pioneer in the research and treatment of digestive disease.

21 Dec 2012

Iron oxide nanoparticles could help track transplanted human endothelial cells

A team of researchers from three medical institutions in Guangzhou, China, have found that iron oxide nanoparticles (INOPS) are a useful contrast agent for in vivo magnetic resonance tracking of transplanted human endothelial cells.

21 Dec 2012

Study examines role of race and ethnicity in stem cell donation

New research examining the role of race and ethnicity in an individual's decision to become a donor for hematopoietic cell transplantation (HCT) identifies several factors associated with varied participation rates in national donor registries across racial/ethnic groups. Results of this first-of-its-kind study are published online today in Blood, the Journal of the American Society of Hematology (ASH).

21 Dec 2012

California Hospital Association honors Sharp HealthCare leader with Award of Merit

Daniel L. Gross , DNSc, RN, Executive Vice President of Hospital Operations for Sharp HealthCare, received the Award of Merit from the California Hospital Association (CHA), at the organization's board meeting today in Newport Beach.

21 Dec 2012

Researchers track adipose tissue-derived stromal cells after transplantation

Using mesenchymal stromal cells derived from adipose (fat) tissues, genetically modified to express a bioluminescent marker, researchers in Italy have tracked cells after transplantation. The cells were followed from their injection into the spleen of mice modeling liver disease, to their characterization as "hepatic precursors," and to their subsequent migration through the spleen before engrafting at regenerating sites in the liver by bioluminescent imaging.

21 Dec 2012

Study examines five varieties of cells after transplantation in the CNS

When different types of cells are transplanted with the intent of having them aid in repairing central nervous system (CNS) trauma, what is the fate and function of those cells? A Belgian research team carried out research aimed at answering this question by determining how five varieties of cells - neural stem cells, mouse embryonic fibroblasts, dendritic cells, bone marrow mononuclear cells (BMMNCs) and splenocytes - functioned and survived after transplantation in the CNS.

21 Dec 2012

AHA/ASA identify top cardiovascular and stroke research advances for 2012

Resuscitation, cell regeneration, a new high blood pressure treatment and developments in devices for treating stroke are among the key scientific findings that make up this year's top cardiovascular and stroke research identified by the American Heart Association and American Stroke Association.

18 Dec 2012

Transplant News and Research

SLU researchers examine health outcomes for obese transplant recipients

Over-expression of NEK2 in cancer cells significantly enhances drug resistance

Donor liver wastage on the increase

Obesity complicates kidney transplantation

Angiotensin II blockade does not seem to provide benefit to kidney transplant recipients

Lower liver quality from donation after cardiac death linked to drop in transplants

Apparent stem cell transplant success in mice may hold promise for people with ALS

New publication focuses on microbiome research in environmental, agricultural and biomedical areas

RPB honors Mass. Eye and Ear ophthalmologist with Senior Scientific Investigator Award

Thoratec to start REVIVE-IT study using HeartMate II Left Ventricular Assist System

Markey practitioner receives Lexington Cancer Foundation grant to continue JSJ program

Heart transplant patient becomes unexpected ambassador for organ donation

Genome sequencing may help identify new targets to treat Pneumocystis pneumonia

Real estate businessman delivers $2.5M gift to University of Chicago Medicine for GI study

Iron oxide nanoparticles could help track transplanted human endothelial cells

Study examines role of race and ethnicity in stem cell donation

California Hospital Association honors Sharp HealthCare leader with Award of Merit

Researchers track adipose tissue-derived stromal cells after transplantation

Study examines five varieties of cells after transplantation in the CNS

AHA/ASA identify top cardiovascular and stroke research advances for 2012

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

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