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New approach holds great promise for developing effective treatments for human mitochondrial diseases

Using existing drugs, such as lithium, to restore basic biological processes in human cells and animal models, researchers may have broken a long-standing logjam in devising effective treatments for human mitochondrial diseases.

21 Jul 2015

New monoclonal antibodies may provide blueprint for effective Alzheimer's disease treatments

Scientists at NYU Langone Medical Center's Center for Cognitive Neurology have evidence that monoclonal antibodies they developed may provide the blueprint for effective treatments for Alzheimer's disease and other neurodegenerative diseases, such as Parkinson's disease.

21 Jul 2015

NDSU assistant professor receives NIH grant to study regulation of transporters in Gram-negative bacteria

Christopher Colbert, assistant professor of biochemistry at North Dakota State University, Fargo, has received a $348,000 grant award from the National Institute of General Medical Sciences of the National Institutes of Health to conduct research on structure-function relationships of iron transport and transcriptional regulation in Gram-negative bacteria.

20 Jul 2015

New study may help identify novel ways to treat immune thrombocytopenia

Immune thrombocytopenia, or ITP, is an autoimmune disease whereby the immune system sends antibodies to attack and destroy the body's platelets--blood cells responsible for controlling bleeding.

20 Jul 2015

New project aims to prevent problems associated with poor nutrition among elderly people

IBA is working on this project as part of the 'Enable' Competence Cluster based at Technische Universität München (TUM) which is developing food for specific age groups and involves various partners at universities and other research institutions.

20 Jul 2015

C2N-8E12 (ABBV-8E12) gets orphan drug designation from FDA for PSP treatment

C2N Diagnostics and AbbVie today announced that the U.S. Food and Drug Administration has granted their investigational recombinant humanized anti-tau antibody, C2N-8E12 (ABBV-8E12), an orphan drug designation for the treatment of progressive supranuclear palsy (PSP).

17 Jul 2015

New research reveals how DNA influences severity of any genetic disease

That two people with the same disease-causing mutation do not get sick to the same extent has been puzzling scientists for decades. Now Professor Andy Fraser and his team have uncovered a key part of what makes every patient different.

17 Jul 2015

Natural supplement may improve quality of life for people who have celiac disease and gluten intolerance

University of Alberta researchers may have found a way to help people with celiac disease enjoy the wide variety of foods they normally have to shun.

17 Jul 2015

TSRI scientists awarded two grants to develop new therapeutic target to reduce latent HIV infection

Scientists from the Florida campus of The Scripps Research Institute have been awarded a pair of grants totaling nearly $2.8 million from the National Institute of Allergy and Infectious Diseases of The National Institutes of Health to develop a new therapeutic agent to reduce latent levels of HIV that hide from the immune system in infected individuals.

17 Jul 2015

Sulfur dioxide air pollutant can cause adverse effects in asthmatics

Emissions of the air pollutant sulfur dioxide have been dramatically decreased during the past 30 years but for some people even a little inhaled sulfur dioxide may still be too much.

17 Jul 2015

Proteins responsible for controlling iron levels in the body also fight against infection

Proteins responsible for controlling levels of iron in the body also play an important role in combatting infection, according to a study published today in Cell Host & Microbe.

17 Jul 2015

BUSM investigators receive MRA's Jackie King Young Investigator Awards

Boston University School of Medicine researchers Neil Joseph Ganem, PhD and Anurag Singh, PhD, each have received the Jackie King Young Investigator Awards from the Melanoma Research Alliance (MRA), the largest private funder of melanoma research. Both serve as assistant professors of pharmacology & experimental therapeutics and medicine.

17 Jul 2015

Increased radiation dose offers survival benefit for men with medium- and high-risk prostate cancer

Increased radiation dose is associated with higher survival rates in men with medium- and high-risk prostate cancer, but not men with low-risk prostate cancer, according to a new study from Penn Medicine published this week in JAMA Oncology. Already-high survival rates for men with low-risk prostate cancer were unaffected by higher radiation dosages compared to lower radiation dosages.

17 Jul 2015

Changes in body temperature can cause sudden cardiac death, finds SFU research

Scientists, including SFU professor Peter Ruben, have found that sudden death caused by cardiac arrhythmia can be triggered by changes in body temperature. The study is published in the Journal of Physiology.

17 Jul 2015

Genetic mutation associated with severe loss of body fat, appearance of premature aging in children identified

Researchers at the Translational Genomics Research Institute have identified a genetic mutation associated with the appearance of premature aging and severe loss of body fat in children.

17 Jul 2015

Scientists discover protein that plays significant role in development of fragile X syndrome

Scientists at VIB and KU Leuven have discovered that the protein APP plays a significant role in the development of fragile X syndrome (FXS) at young stages. They identified an unexpected biological pathway as a promising target to ameliorate deficits associated with FXS and autism. The results have recently been published in Neuron, one of the most influential journals in the field of neuroscience.

16 Jul 2015

UW researchers help develop new compound to combat malaria

An international team of scientists — led by researchers from the University of Washington and two other institutions — has announced that a new compound to fight malaria is ready for human trials. In a new paper published July 15 in Science Translational Medicine, they show that this compound is the first to cripple a critical protein that the malaria parasite needs to survive at different stages of its complex life cycle, and is suitable for clinical tests in humans.

16 Jul 2015

New research offers potential for early intervention to prevent neurodegenerative diseases

New research led by investigators at Beth Israel Deaconess Medical Center provides the first direct evidence linking traumatic brain injury to Alzheimer's disease and chronic traumatic encephalopathy (CTE) -- and offers the potential for early intervention to prevent the development of these debilitating neurodegenerative diseases.

16 Jul 2015

Canadian researchers discover how HIV evades the body's antiviral responses

A Canadian research team at the IRCM in Montreal, led by molecular virologist Eric A. Cohen, PhD, made a significant discovery on how HIV escapes the body's antiviral responses. The team uncovered how an HIV viral protein known as Vpu tricks the immune system by using its own regulatory process to evade the host's first line of defence.

16 Jul 2015

Research could lead to new approaches to treating spinal cord and brain injuries

Many an injury will heal, but the damaged spinal cord is notoriously recalcitrant. There's new hope on the horizon, though. A team of researchers led by the University of South Carolina's Jeff Twiss just reported an innate repair mechanism in central nervous system axons that might be harnessed to regenerate nerves after brain or spinal cord injuries.

16 Jul 2015

G Protein News and Research

New approach holds great promise for developing effective treatments for human mitochondrial diseases

New monoclonal antibodies may provide blueprint for effective Alzheimer's disease treatments

NDSU assistant professor receives NIH grant to study regulation of transporters in Gram-negative bacteria

New study may help identify novel ways to treat immune thrombocytopenia

New project aims to prevent problems associated with poor nutrition among elderly people

C2N-8E12 (ABBV-8E12) gets orphan drug designation from FDA for PSP treatment

New research reveals how DNA influences severity of any genetic disease

Natural supplement may improve quality of life for people who have celiac disease and gluten intolerance

TSRI scientists awarded two grants to develop new therapeutic target to reduce latent HIV infection

Sulfur dioxide air pollutant can cause adverse effects in asthmatics

Proteins responsible for controlling iron levels in the body also fight against infection

BUSM investigators receive MRA's Jackie King Young Investigator Awards

Increased radiation dose offers survival benefit for men with medium- and high-risk prostate cancer

Changes in body temperature can cause sudden cardiac death, finds SFU research

Genetic mutation associated with severe loss of body fat, appearance of premature aging in children identified

Scientists discover protein that plays significant role in development of fragile X syndrome

UW researchers help develop new compound to combat malaria

New research offers potential for early intervention to prevent neurodegenerative diseases

Canadian researchers discover how HIV evades the body's antiviral responses

Research could lead to new approaches to treating spinal cord and brain injuries

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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