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Researchers develop new kind of CRISPR screen technology to target RNA

CRISPR-based genetic screens have helped scientists identify genes that are key players in sickle-cell anemia, cancer immunotherapy, lung cancer metastasis, and many other diseases.

16 Mar 2020

New method will enable production of tailor-made vaccines

Vaccines can be far more targeted and effective than they are today. A new method will allow us to develop new vaccines more cheaply and efficiently and perhaps get one step ahead of bacteria.

13 Mar 2020

NCAM2 protein is a vital factor in the formation of cerebral cortex, neuronal morphogenesis

The molecule NCAM2, a glycoprotein from the superfamily of immunoglobulins, is a vital factor in the formation of the cerebral cortex, neuronal morphogenesis and formation of neuronal circuits in the brain, as stated in the new study published in the journal Cerebral Cortex.

13 Mar 2020

Preserving kidney function in patients with diabetic kidney disease

Diabetic kidney disease, which affects between 20 to 40 percent of people with diabetes, is a serious complication that can ultimately lead to end-stage kidney disease--a life-threatening condition that requires either dialysis or kidney transplant.

13 Mar 2020

People want more money, control in exchange for genomic data

Genomic data donated by the public is valuable for the companies that collect it. But a recent survey finds that once people are aware of issues surrounding the use and security of genetic information, people are more concerned about how it might be used and expect to be better compensated for providing it.

11 Mar 2020

Blood test for microbial DNA could warn of cancer

A new study published in the journal Nature on March 11, 2020, could transform the currently held views on cancer causation and diagnosis. The researchers have come up with a new technique to detect the presence and type of cancer by looking at microbial DNA circulating in the blood of the person being screened.

11 Mar 2020

Microbial DNA in the blood could help identify who has cancer

When Gregory Poore was a freshman in college, his otherwise healthy grandmother was shocked to learn that she had late-stage pancreatic cancer. The condition was diagnosed in late December. She died in January.

11 Mar 2020

Scientists receive €2.45 million funding for leukemia research

Leukemia stem cells are considered to be the starting point of leukemia; their elimination is a basic prerequisite for a successful long-term therapy. Scientists at Heidelberg University Hospital, the Heidelberg Institute for Stem Cell Technology and Experimental Medicine at the German Cancer Research Center, the German Cancer Research Center and the European Molecular Biology Laboratory have now obtained research funding of €2.45 million from the German Federal Ministry of Education and Research as part of the junior research alliance LeukoSyStem.

11 Mar 2020

Scientists create new tool to study the genetic underpinnings of brain disorders

Scientists at the UNC School of Medicine and colleagues created a new computational tool called H-MAGMA to study the genetic underpinnings of nine brain disorders, including the identification of new genes associated with each disorder.

9 Mar 2020

Newly identified genetic signatures in common pediatric cancer pave way for precision medicine

Researchers with Nemours Children's Health System utilized Next Generation Sequencing (NGS) to more precisely identify genomic characteristics of leukemias in children, the most common childhood cancer.

5 Mar 2020

Coronavirus is mutating with a second strain identified by scientists

The coronavirus is mutating as scientists identified a second strain, which is more aggressive and contagious.

5 Mar 2020

Two genome sequences of coronavirus (COVID-19) show possible internal transmission

The coronavirus disease (COVID-19) is rapidly spreading around the globe. With the high infection rate and spread of the virus to more than 80 countries, scientists are racing to study the nature of the virus, in the hopes of finding new vaccines and therapeutics.

4 Mar 2020

Inhibiting energy production in immune T-cells allows some tumors to escape treatment

A small molecule that inhibits energy production in immune T-cells allows some tumors to escape treatment with an immunotherapy called PD-1 blockade therapy, says a study in mice published today in eLife.

3 Mar 2020

Subpopulations of leukemic cells present at diagnosis can cause relapse in children with ALL

Scientists at St. Jude Children's Research Hospital and Princess Margaret Cancer Centre in Toronto, Canada, have reported that subpopulations of leukemic cells present at diagnosis can cause relapse in children with acute lymphoblastic leukemia.

3 Mar 2020

Two common Staph bacteria living on human skin exacerbate Netherton syndrome

Netherton syndrome, a rare skin disease caused by a single genetic mutation, is exacerbated by the presence of two common Staphylococcal bacteria living on human skin, one of which was previously thought to only offer protective properties, report University of California San Diego School of Medicine researchers.

3 Mar 2020

Nursing home outbreak spotlights coronavirus risk in elder care facilities

An outbreak of coronavirus disease in a nursing home near Seattle is prompting urgent calls for precautionary tactics at America's elder care facilities, where residents are at heightened risk of serious complications from the illness because of the dual threat of age and close living conditions.

2 Mar 2020

First human vaginal non-redundant gene catalog released

University of Maryland School of Medicine's Institute for Genome Sciences researchers have created the first catalog of genes that comprise the community of microbes, which inhabit the human vagina.

26 Feb 2020

New method to deliver an immune system 'uncloaking' device directly to cancer cells

Scientists at Johns Hopkins report they have designed and successfully tested an experimental, super small package able to deliver molecular signals that tag implanted human cancer cells in mice and make them visible for destruction by the animals' immune systems.

26 Feb 2020

Promega introduces Wizard HMW DNA Extraction Kit ahead of AGBT 2020

Promega, a global biotechnology manufacturer, today launched its new Wizard HMW DNA Extraction Kit for researchers working with large fragments of genomic DNA.

From Promega Corporation 25 Feb 2020

DNA topological problems may cause lymphoma, study shows

Researchers from the Spanish National Cancer Research Centre, Madrid, and the Andalusian Molecular Biology and Regenerative Medicine Centre, Seville, published today a paper in Nature Communications that shows that DNA topological problems may cause endogenous DNA breaks that have a causal relationship with cancer.

24 Feb 2020