Mutation News and Research

RSS

Nervous system relies on guidance cues for neuronal axons to reach destinations

Similar to the dozens of Sherpas that guide hikers up treacherous Himalayan mountains to reach a summit, the nervous system relies on elaborate timing and location of guidance cues for neuronal axons--threadlike projections--to successfully reach their destinations in the body.

25 Mar 2019

Role of immunological imprinting in elicitation of new antibodies

We are repeatedly exposed to the influenza virus via infections, vaccinations and our communal environments. The annual flu shot is believed to be the best line of defense, and doctors recommend vaccinations every year because the flu virus is in a constant state of adaptation and mutation, rendering older vaccines obsolete.

21 Mar 2019

New computer program developed by TGen lights up cancer-causing genetic mutations

By conjuring the spell "Lumos!" wizards in the mythical world of Harry Potter could light up the tip of their magic wands and illuminate their surroundings. So, too, does LumosVar, a computer program developed by the Translational Genomics Research Institute, "light up" cancer-causing genetic Var-ients, or mutations, illuminating how physicians might best treat their patients.

21 Mar 2019

Study identifies gene variant associated with accelerated cellular aging

It is well known that psychiatric stress is associated with accelerated aging. Now, a new study shows that a gene mutation interacts with multiple types of psychiatric stress including post-traumatic stress disorder (PTSD), pain and sleep disturbances in association with cellular aging.

20 Mar 2019

Active substance from plant could turn into a ray of hope against eye tumors

An active substance that has been known for 30 years could unexpectedly turn into a ray of hope against eye tumors.

20 Mar 2019

Royal Holloway professors to lead new to research into curing Neurofibromatosis type 1

Linda Popplewell, Lecturer in Biomedical Sciences, and world-renowned Professor George Dickson, from the School of Biological Sciences, both at Royal Holloway, will lead a team looking for a treatment for NF1, a genetic disorder that causes tumors to form on nerve tissue.

20 Mar 2019

Mother's diet during pregnancy can impact lung-specific genes of her offspring

Children born to women pregnant during the Dutch famine were more likely to have a constellation of health problems including cardiovascular disease and asthma, but the exact mechanisms that cause this epigenetic inheritance have not been fully explored.

20 Mar 2019

New analysis reveals precision oncology insights for colorectal cancer

Next-generation sequencing of tumor DNA from patients with colorectal cancer revealed genetic alterations that were linked to different survival and treatment outcomes in an analysis led by a University of North Carolina Lineberger Comprehensive Cancer Center researcher.

20 Mar 2019

Study illuminates how hot spots of genetic variation evolved in the human genome

What makes one person different from one another, and how did these differences evolve? A study by University at Buffalo biologists is illuminating one aspect of this complicated question. The research examines hot spots of genetic variation within the human genome, examining the sections of our DNA that are most likely to differ significantly from one person to another.

20 Mar 2019

AeroForm Tissue Expanders makes breast reconstruction after mastectomy more comfortable

Henry Ford Cancer Institute is the first in Michigan to offer a needle-free, patient-controlled tissue expansion system for women undergoing breast reconstruction after mastectomy.

20 Mar 2019

Key discoveries could shed light on retinoblastoma

Retinoblastoma is a tumor of the retina that generally affects children under 5 years of age and accounts for approximately 4% of childhood cancers. If not diagnosed early, retinoblastoma may result in loss of one or both eyes and can be fatal.

15 Mar 2019

Antibody-drug conjugate effectively targets surface protein in childhood neuroblastomas

Physician-scientists in the Cancer Center at Children's Hospital of Philadelphia have developed a preclinical, potent therapy attached to an antibody that targets a surface protein expressed in most childhood neuroblastomas, effectively killing cancer cells.

14 Mar 2019

PNAS publishes results of pilot study for early detection of liver cancer

Today, Proceedings of the National Academy of Sciences published the results of a pilot study for early detection of liver cancer in a cohort of HBV carriers, who are at risk for developing this disease.

13 Mar 2019

Access to real-time genotype data influences prescriber behavior after PCI

Today, in a late-breaking featured clinical research session at the American College of Cardiology Scientific Sessions 2018, researchers from Penn Medicine present first-of-its-kind data on the impact of real-time CYP2C19 genotype results when prescribing antiplatelet drugs in the clinic.

13 Mar 2019

Gene behind mitochondrial disease has more varied effects than previously thought

For more than two decades, mutations in a gene located in the DNA of mitochondria have been classified as a mitochondrial disease and linked to a particular set of symptoms.

12 Mar 2019

Researchers identify potential therapeutic target for blocking early atherosclerosis in progeria

Researchers at the Centro Nacional de Investigaciones Cardiovasculares and the Universidad de Oviedo have discovered a new molecular mechanism involved in the premature development of atherosclerosis in mice with Hutchinson-Gilford progeria syndrome.

12 Mar 2019

Killer flu pandemic is inevitable and world is not prepared, says WHO

The World Health Organisation has said that the world is not prepared for a global flu pandemic and that resources are inadequate.

12 Mar 2019

Researchers develop new method to boost efficiency of CRISPR gene editing in DMD

Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases.

7 Mar 2019

Johns Hopkins researchers to present latest findings on TB and HIV at CROI 2019

Johns Hopkins Medicine researchers are attending the annual Conference on Retroviruses and Opportunistic Infections, where they are sharing their latest findings in the ongoing battle against HIV/AIDS and related infectious diseases with other top basic, translational and clinical researchers from around the world.

7 Mar 2019

Common fungus found on skin may cause inflammatory bowel disease

Therapies that target certain commensal fungi could provide a new way of treating inflammatory bowel disease (IBD), according to researchers.

6 Mar 2019

Mutation News and Research

Nervous system relies on guidance cues for neuronal axons to reach destinations

Role of immunological imprinting in elicitation of new antibodies

New computer program developed by TGen lights up cancer-causing genetic mutations

Study identifies gene variant associated with accelerated cellular aging

Active substance from plant could turn into a ray of hope against eye tumors

Royal Holloway professors to lead new to research into curing Neurofibromatosis type 1

Mother's diet during pregnancy can impact lung-specific genes of her offspring

New analysis reveals precision oncology insights for colorectal cancer

Study illuminates how hot spots of genetic variation evolved in the human genome

AeroForm Tissue Expanders makes breast reconstruction after mastectomy more comfortable

Key discoveries could shed light on retinoblastoma

Antibody-drug conjugate effectively targets surface protein in childhood neuroblastomas

PNAS publishes results of pilot study for early detection of liver cancer

Access to real-time genotype data influences prescriber behavior after PCI

Gene behind mitochondrial disease has more varied effects than previously thought

Researchers identify potential therapeutic target for blocking early atherosclerosis in progeria

Killer flu pandemic is inevitable and world is not prepared, says WHO

Researchers develop new method to boost efficiency of CRISPR gene editing in DMD

Johns Hopkins researchers to present latest findings on TB and HIV at CROI 2019

Common fungus found on skin may cause inflammatory bowel disease

Improving healthcare sustainability through carbon data

Managing vibration in IVF laboratories

A New Approach to Preventing Bladder Cancer Recurrence

Latest News