immunity News and Research

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Dynamic causal modeling for future projection of the COVID-19 pandemic

A new study utilizes dynamic causal modeling to predict the effects of letting SARS-CoV-2 sweep through a largely vaccinated population.

10 Oct 2021

Lipids, COVID-19, and host immunity

A new study from a team of researchers at the University of Pennsylvania examines the role played by lipids in this disease.

10 Oct 2021

Powerful neutralizing antibody against SARS-CoV-2 variants of concern

A new paper discusses a new antibody with potent neutralizing activity against the ancestral SARS-CoV-2 strain, as well as newer variants of SARS-CoV-2.

10 Oct 2021

Low risk of severe COVID-19 after first dose of Pfizer and AstraZeneca vaccines in Scotland

Hospital admissions and deaths due to COVID-19 were drastically reduced at two weeks or more from the first dose of either the Pfizer or AstraZeneca vaccine.

10 Oct 2021

Severe influenza outbreak expected in the United States after relaxation of COVID control measures

New research warns that the United States could experience a severe influenza outbreak after public health measures like face masks and social distancing are lifted.

8 Oct 2021

Study supports efficacy and safety of lung-selective nanotherapy against SARS-CoV-2 infection

A new preprint shows the potential role of a host protease cathepsin L inhibitor, which mediates viral entry into the host cell by its effect on the viral spike protein.

8 Oct 2021

Covid immunity through infection or vaccination: Are they equal?

Dr. Aaron Kheriaty, a University of California-Irvine psychiatry professor, felt he didn't need to be vaccinated against covid because he'd fallen ill with the disease in July 2020.

8 Oct 2021

Oral and intranasal COVID-19 vaccines show promising results in hamster model

A new preprint discusses the protective effect of an oral adenovirus-vectored vaccine based on the SARS-CoV-2 spike against viral transmission and disease in hamsters.

8 Oct 2021

mRNA vaccination associated with decreased risk of COVID-19 infection and hospitalization in U.S. veterans

Researchers from the U.S. Veterans Affairs have examined the U.S. effort to vaccinate its Veteran population to investigate further.

8 Oct 2021

Assay to assess and quantify presence of RBD-directed antibodies against SARS-CoV-2 following vaccination

Researchers from Roche Diagnostics have been testing a new assay known as the Elecsys assay.

8 Oct 2021

Scientists study immune response to COVID-19 in patients with different levels of disease severity

Researchers from Skoltech, U.S. companies VirIntel and Argentys Informatics, and two Russian Academy of Sciences institutes have studied the immune response to COVID-19 in patients with different levels of disease severity.

8 Oct 2021

Novel peptide-drug conjugate enhances the efficacy of immunotherapy in preclinical cancer models

A peptide-drug conjugate that targets the acidic environment of cancer cells enhanced the efficacy of immune checkpoint inhibitors in preclinical cancer models, according to results presented at the AACR-NCI-EORTC Virtual International Conference on Molecular Targets and Cancer Therapeutics, held October 7-10, 2021.

7 Oct 2021

BNT162b2 COVID vaccine humoral response substantially reduced after 6 months

The rollout of vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is expanding worldwide. However, little is known about the duration of protection offered by these vaccines. Real-world data on the kinetics of antibodies are beginning to appear, but a holistic picture of immunity duration is still not available.

7 Oct 2021

New film campaign encourages people to get free flu vaccine and COVID-19 booster jab

Those eligible for the free flu vaccine and COVID-19 booster jab are being urged to book their appointments as soon as possible in a new film campaign launched today [Friday 8 October] aiming to help people give themselves and their loved ones the best possible protection this winter.

7 Oct 2021

non-RBD mutation in SARS-CoV-2 variants enhances resistance to neutralizing antibodies

Researchers from Ohio State University have been investigating mutations in the rest of the spike protein, particularly the Q677H mutation.

7 Oct 2021

Study suggests continued delta variant outbreaks unless vaccination reaches high coverage levels in adults and children

Researchers have conducted a mathematical modeling study to understand how expanding vaccination to younger age groups may reduce the increasing case numbers.

7 Oct 2021

After 5 months, Pfizer-BioNTech COVID vaccine remains highly protective against hospitalization and death

The study "Effectiveness of mRNA BNT162b2 COVID-19 vaccine up to 6 months in a large integrated health system in the USA: a retrospective cohort study" is published in the journal The Lancet.

7 Oct 2021

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

A new study published on the medRxiv* preprint server focused on a patient with a persistent symptomatic viral infection for over a year. Researchers amplified sub-genomic transcripts for the E gene (sgE) using nasopharyngeal samples of the patient infected with SARS-CoV-2 over the course of 335 days.

6 Oct 2021

Study shows new antibody resistant variants can emerge in patients treated with monoclonal antibodies

A new study, published on the medRxiv* preprint server, suggested that selective pressures induced by the administration of monoclonal antibodies (Bamlanivimab) may require increased genomic surveillance to identify and control the spread of therapy-induced variants.

6 Oct 2021

Research on twins indicates strong genetic influences in COVID-19

A new study discusses the strong possibility of multifactorial causation for SARS-CoV-2 infection using data from twin studies.

6 Oct 2021

immunity News and Research

Dynamic causal modeling for future projection of the COVID-19 pandemic

Lipids, COVID-19, and host immunity

Powerful neutralizing antibody against SARS-CoV-2 variants of concern

Low risk of severe COVID-19 after first dose of Pfizer and AstraZeneca vaccines in Scotland

Severe influenza outbreak expected in the United States after relaxation of COVID control measures

Study supports efficacy and safety of lung-selective nanotherapy against SARS-CoV-2 infection

Covid immunity through infection or vaccination: Are they equal?

Oral and intranasal COVID-19 vaccines show promising results in hamster model

mRNA vaccination associated with decreased risk of COVID-19 infection and hospitalization in U.S. veterans

Assay to assess and quantify presence of RBD-directed antibodies against SARS-CoV-2 following vaccination

Scientists study immune response to COVID-19 in patients with different levels of disease severity

Novel peptide-drug conjugate enhances the efficacy of immunotherapy in preclinical cancer models

BNT162b2 COVID vaccine humoral response substantially reduced after 6 months

New film campaign encourages people to get free flu vaccine and COVID-19 booster jab

non-RBD mutation in SARS-CoV-2 variants enhances resistance to neutralizing antibodies

Study suggests continued delta variant outbreaks unless vaccination reaches high coverage levels in adults and children

After 5 months, Pfizer-BioNTech COVID vaccine remains highly protective against hospitalization and death

SARS-CoV-2 evolution promoted by long-term infection in patient with B cell depletion

Study shows new antibody resistant variants can emerge in patients treated with monoclonal antibodies

Research on twins indicates strong genetic influences in COVID-19

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